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Breaking antimicrobial resistance by disrupting extracytoplasmic protein folding.

Autor: Furniss RCD; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom., Kaderabkova N; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom.; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Barker D; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom., Bernal P; Department of Microbiology, Faculty of Biology, Universidad de Sevilla, Seville, Spain., Maslova E; Division of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Antwi AAA; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom., McNeil HE; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Pugh HL; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Dortet L; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom.; Department of Bacteriology-Hygiene, Bicêtre Hospital, Assistance Publique - Hôpitaux de Paris, Le Kremlin-Bicêtre, France.; EA7361 'Structure, Dynamics, Function and Expression of Broad-spectrum β-lactamases', Paris-Sud University, LabEx Lermit, Faculty of Medicine, Le Kremlin-Bicêtre, France.; French National Reference Centre for Antibiotic Resistance, Le Kremlin-Bicêtre, France., Blair JMA; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom., Larrouy-Maumus G; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom., McCarthy RR; Division of Biosciences, Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom., Gonzalez D; Laboratoire de Microbiologie, Institut de Biologie, Université de Neuchâtel, Neuchâtel, Switzerland., Mavridou DAI; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom.; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States.; John Ring LaMontagne Center for Infectious Diseases, University of Texas at Austin, Austin, United States.

Publikováno v: ELife [Elife] 2022 Jan 13; Vol. 11. Date of Electronic Publication: 2022 Jan 13.