Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Kachio Tasaka"'
Autor:
Miho Tanaka, Shin-ichi Yazaki, Harumi Fukazawa, Akio Mimura, Koji Nishio, Hisako Yamamoto, Sadaharu Ui, Kachio Tasaka, Mika Himeji, Takashi Ohtsuki
Publikováno v:
Cancer Letters. 245:269-274
Methanol extract from cultured Scutellaria baicalensis cells inhibited the proliferation of human monocytic leukemia cell line THP-1 and human osteogenic sarcoma cell line HOS. The inhibitory effects of baicalin, baicalein and wogonin, the three majo
Autor:
Kachio Tasaka, Jiro Ichikawa, Hongri Xu, Atsushi Okamoto, Ko Okumura, Hideo Yagita, Hideoki Ogawa, Atsuhito Nakao, Takashi Ando, Keisuke Masuyama
Publikováno v:
Biochemical and Biophysical Research Communications. 318:422-427
TNF-like weak inducer of apoptosis (TWEAK), a member of the tumor necrosis factor (TNF) family, is a multifunctional cytokine that regulates cellular proliferation, angiogenesis, inflammation, and apoptosis. In this study, we investigated the effect
Publikováno v:
The Journal of Immunology. 167:2487-2495
Interferon-γ plays a crucial role in induction of Th1 response but is predominantly a negative regulator of B cell differentiation and Th2 response, so it is a key molecule in determining cellular or humoral immunity. In this study, we demonstrate t
Publikováno v:
International Immunopharmacology. 1:63-74
We observed that dimethyl sulfoxide (DMSO) induced apoptotic changes in the EL-4 murine lymphoma cell line and that effect was dependent on the concentration and time period. Incubating cells over a period of 18 h, 2.5% DMSO was found to induce sub-G
Publikováno v:
The Journal of Immunology. 165:6262-6269
Mast cells play a critical role in host immune responses and are implicated in the pathogenesis of allergic inflammation. Though mouse mast cell line MC/9 expresses cell surface Fas Ag and is sensitive to Fas-induced apoptosis, activated MC/9 cells a
Publikováno v:
Journal of Applied Toxicology. 20:471-475
In recent immunological studies, it has been suggested that trichloroethylene (TCE) participates in the onset of pneumatosis cystoides intestinalis (PCI) through a certain mechanism; however, the mechanism by which it develops remains unknown. Based
Autor:
Hirofumi Naganuma, Hideaki Nukui, Hideji Yoshikawa, Atsushi Sasaki, Tomoyuki Kawataki, Kachio Tasaka
Publikováno v:
Neuropathology. 20:161-169
The expression of thrombospondin-1 (TSP-1) and its role in gliomas have not been well examined. In the present study TSP-1 expression in a panel of malignant glioma cell lines and the expression of TSP-1 and transforming growth factor (TGF-beta) prot
Autor:
Kazutake Seki, Yoshiki Hamada, Hideshi Yoshikawa, Noriya Akamatsu, Kachio Tasaka, Kazuhiko Shiiki
Publikováno v:
Cancer Chemotherapy and Pharmacology. 45:199-206
Purpose: Osteosarcoma is a common malignant tumor. The first choice of treatment plan for osteosarcoma is chemotherapy. In particular, preoperative chemotherapy is most important in clinical treatment in orthopedics. In these chemotherapies, multiple
Publikováno v:
Parasite Immunology. 21:583-593
T cell clones (B1, B21, B7, A25) specific to the soluble egg antigen (SEA) of Schistosoma japonicum were established from C3H/He mice immunized with SEA. These clones belonged to CD3+ , CD4+ and CD8−Th1 cells, showing TCR-γδ−, TCR-αβ+ and Vβ
Publikováno v:
Blood. 90:1911-1919
The interleukin-3 (IL-3)–dependent murine bone marrow–derived cell line FDC-P2/185-4 (185-4) undergoes apoptosis when IL-3 is withdrawn from culture medium. Previous results from our studies indicated that a high concentration of aggregated mouse