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pro vyhledávání: '"Kacee A DiTacchio"'
Autor:
Kacee Ann DiTacchio, Diana Kalinowska, Anand Rajamani Saran, Ashley Byrne, Christopher Vollmers, Luciano DiTacchio
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: The liver is a key regulator of systemic energy homeostasis whose proper function is dependent on the circadian clock. Here, we show that livers deficient in the oscillator component JARID1a exhibit a dysregulation of genes involved in energ
Externí odkaz:
https://doaj.org/article/239ad061b3b74c7eb716e921eb784b99
Autor:
Kacee A. DiTacchio, Luciano DiTacchio
A powerful use of gene editing technology is the generation of genetic-null (knockout) mutants of human immortalized cell lines. However, a problem that arises in the process of generating such edited lines is that to ensure edit homogeneity, clonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fa4ea7c33c49b94ff40a305d7a2702
https://doi.org/10.1101/2022.05.25.493512
https://doi.org/10.1101/2022.05.25.493512
Autor:
Christopher Vollmers, Kacee A. DiTacchio, Luciano DiTacchio, Anand R. Saran, Ashley Byrne, Diana Kalinowska
Publikováno v:
Cell Rep
Cell Reports, Vol 31, Iss 8, Pp-(2020)
Cell Reports, Vol 31, Iss 8, Pp-(2020)
Summary The liver is a key regulator of systemic energy homeostasis whose proper function is dependent on the circadian clock. Here, we show that livers deficient in the oscillator component JARID1a exhibit a dysregulation of genes involved in energy
Autor:
Diana Kalinowska, Ashley Byrne, Anand R. Saran, Christopher Vollmers, Kacee A. DiTacchio, Luciano DiTacchio
Publikováno v:
SSRN Electronic Journal.
The liver is a key regulator of systemic energy homeostasis whose proper function is dependent on the circadian clock. Here, we show that livers deficient in the oscillator component JARID1a exhibit a dysregulation of genes involved in energy metabol
Publikováno v:
Energy Balance and Cancer ISBN: 9783319167329
Circadian rhythms are patterns of behavior, physiology, and metabolism that occur within a period of approximately 24 h. These rhythms are generated endogenously, but synchronize to external cues, thus enabling organisms to beneficially align physiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608632f736c352383589f96066e356a4
https://doi.org/10.1007/978-3-319-16733-6_1
https://doi.org/10.1007/978-3-319-16733-6_1
Publikováno v:
J Alzheimers Dis
Metabolic dysfunction exacerbates Alzheimer's disease (AD) incidence and progression. Here we report that activation of the AMPK pathway, a common target in the management of diabetes, results in gender-divergent cognitive effects in a murine model o