A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo .

Autor: Nguyen HA; The Jesse Brown VA Medical Center, Chicago, Illinois.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Su Y; The Jesse Brown VA Medical Center, Chicago, Illinois.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Zhang JY; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Antanasijevic A; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Caffrey M; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Schalk AM; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Liu L; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois., Rondelli D; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Oh A; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Mahmud DL; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Bosland MC; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Kajdacsy-Balla A; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Peirs S; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Lammens T; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., Mondelaers V; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., De Moerloose B; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., Goossens S; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Schlicht MJ; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Kabirov KK; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Lyubimov AV; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Merrill BJ; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Saunthararajah Y; Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation, Cleveland, Ohio., Van Vlierberghe P; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium. Lavie@uic.edu pieter.vanvlierberghe@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Lavie A; The Jesse Brown VA Medical Center, Chicago, Illinois. Lavie@uic.edu pieter.vanvlierberghe@ugent.be.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.

Publikováno v: Cancer research [Cancer Res] 2018 Mar 15; Vol. 78 (6), pp. 1549-1560. Date of Electronic Publication: 2018 Jan 17.

Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs.

Autor: Kabirov KK; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL 60612, USA., Kapetanovic IM, Benbrook DM, Dinger N, Mankovskaya I, Zakharov A, Detrisac C, Pereira M, Martín-Jiménez T, Onua E, Banerjee A, van Breemen RB, Nikolić D, Chen L, Lyubimov AV

Publikováno v: Drug and chemical toxicology [Drug Chem Toxicol] 2013 Jul; Vol. 36 (3), pp. 284-95. Date of Electronic Publication: 2012 Sep 05.

Assessment of oral toxicity and safety of 9-cis-UAB30, a potential chemopreventive agent, in rat and dog studies.

Autor: Lindeblad M; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois 60612, USA., Kapetanovic IM, Kabirov KK, Dinger N, Mankovskaya I, Morrisey R, Martín-Jiménez T, Lyubimov A

Publikováno v: Drug and chemical toxicology [Drug Chem Toxicol] 2011 Jul; Vol. 34 (3), pp. 300-10.

In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes.

Autor: Jackson JP; CellzDirect/Invitrogen Corporation, Austin, TX 78754, United States., Kabirov KK, Kapetanovic IM, Lyubimov A

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2009 May 15; Vol. 179 (2-3), pp. 263-72. Date of Electronic Publication: 2008 Dec 16.

[Predicting the parameters of the olfactory effects of benzene derivatives on the basis of their electron-nuclear structure].

Autor: Tepikina LA, Liubimov AV, Aĭnbinder NE, Kabirov KK

Publikováno v: Gigiena i sanitariia [Gig Sanit] 1990 Nov (11), pp. 25-6.