Effects of bacterial and presystemic nitroreductase metabolism of 2-chloro-5-nitro-N-phenylbenzamide on its mutagenicity and bioavailability

Autor: Kapetanovic, Izet M., Lyubimov, Alexander V., Kabirova, Elena V., Kabirov, Kasim K., Rasay, Laura, Swezey, Robert, Green, Carol, Kopelovich, Levy

Publikováno v: In Chemico-Biological Interactions 15 April 2012 197(1):16-22

In vitro assessment of P450 induction potential of novel chemopreventive agents SR13668, 9-cis-UAB30, and pentamethychromanol in primary cultures of human hepatocytes

Autor: Jackson, Jonathan P., Kabirov, Kasim K., Kapetanovic, Izet M., Lyubimov, Alexander

Publikováno v: In Chemico-Biological Interactions 2009 179(2):263-272

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A Novel l-Asparaginase with low l-Glutaminase Coactivity Is Highly Efficacious against Both T- and B-cell Acute Lymphoblastic Leukemias In Vivo .

Autor: Nguyen HA; The Jesse Brown VA Medical Center, Chicago, Illinois.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Su Y; The Jesse Brown VA Medical Center, Chicago, Illinois.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Zhang JY; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Antanasijevic A; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Caffrey M; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Schalk AM; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Liu L; Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois., Rondelli D; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Oh A; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Mahmud DL; Division of Hematology/Oncology, University of Illinois Hospital and Health Sciences System, Chicago, Illinois., Bosland MC; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Kajdacsy-Balla A; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Peirs S; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Lammens T; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., Mondelaers V; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., De Moerloose B; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium., Goossens S; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Schlicht MJ; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois., Kabirov KK; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Lyubimov AV; Toxicology Research Laboratory, Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois., Merrill BJ; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,., Saunthararajah Y; Department of Translational Hematology & Oncology Research, Cleveland Clinic Foundation, Cleveland, Ohio., Van Vlierberghe P; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium. Lavie@uic.edu pieter.vanvlierberghe@ugent.be.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Lavie A; The Jesse Brown VA Medical Center, Chicago, Illinois. Lavie@uic.edu pieter.vanvlierberghe@ugent.be.; Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois,.

Publikováno v: Cancer research [Cancer Res] 2018 Mar 15; Vol. 78 (6), pp. 1549-1560. Date of Electronic Publication: 2018 Jan 17.