Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Kabir H BISWAS"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Anti-COVID19 drugs, such as nirmatrelvir, have been developed targeting the SARS-CoV-2 main protease, Mpro, based on the critical requirement of its proteolytic processing of the viral polyproteins into functional proteins essential for viral replica
Externí odkaz:
https://doaj.org/article/c2c98b885de745f1b68668b34a2116ae
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The need for the early detection of emerging pathogenic viruses and their newer variants has driven the urgent demand for developing point-of-care diagnostic tools. Although nucleic acid-based methods such as reverse transcription-quantitative polyme
Externí odkaz:
https://doaj.org/article/d7f71b2cf6d14559adce15cf1f414d16
Autor:
Naushad Ahmad Khan, Mohammad Asim, Kabir H. Biswas, Amani N Alansari, Harman Saman, Mohammad Zahid Sarwar, Kudaibergen Osmonaliev, Shahab Uddin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-35 (2023)
Abstract Lung cancer remains the leading cause of cancer-related deaths globally, and the survival rate remains low despite advances in diagnosis and treatment. The progression of lung cancer is a multifaceted and dynamic phenomenon that encompasses
Externí odkaz:
https://doaj.org/article/6be352521fc7416ab3befa2756817beb
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1966-1977 (2023)
The SARS-CoV-2 Omicron variant containing 15 mutations, including the unique Q493R, in the spike protein receptor binding domain (S1-RBD) is highly infectious. While comparison with previously reported mutations provide some insights, the mechanism u
Externí odkaz:
https://doaj.org/article/b9d3377bbdf941989fe6611cfdae5ffd
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3665-3671 (2023)
Background: SARS-CoV-2 variants continue to spread throughout the world and cause waves of COVID-19 infections. It is important to find effective antiviral drugs to combat SARS-CoV-2 and its variants. The main protease (Mpro) of SARS-CoV-2 is a promi
Externí odkaz:
https://doaj.org/article/0063b44eb4a949979fb0f5968a1c87a2
Autor:
Anupriya M. Geethakumari, Wesam S. Ahmed, Saad Rasool, Asma Fatima, S. M. Nasir Uddin, Mustapha Aouida, Kabir H. Biswas
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-13 (2022)
The main protease (Mpro) of SARS-CoV-2 is an important target for COVID-19 therapy. Here, a pair of genetically encoded BRET-based sensors for detecting Mpro activity are generated by sandwiching N-terminal autocleavage sites in between the mNeonGree
Externí odkaz:
https://doaj.org/article/61108c66f7454dde81a54b7b18085740
Autor:
Syed Abdullah Basit, Rizwan Qureshi, Saleh Musleh, Reto Guler, M. Sohel Rahman, Kabir H. Biswas, Tanvir Alam
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
COVID-19 has taken a huge toll on our lives over the last 3 years. Global initiatives put forward by all stakeholders are still in place to combat this pandemic and help us learn lessons for future ones. While the vaccine rollout was not able to curb
Externí odkaz:
https://doaj.org/article/4ad0e0ed03f7438587dd9aa77264a858
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/21ac585a10cb4b83ae71f0db4fe54086
Autor:
Naushad Ahmad Khan, Mohammad Asim, Ayman El-Menyar, Kabir H. Biswas, Sandro Rizoli, Hassan Al-Thani
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Developing effective disease-modifying therapies for neurodegenerative diseases (NDs) requires reliable diagnostic, disease activity, and progression indicators. While desirable, identifying biomarkers for NDs can be difficult because of the complex
Externí odkaz:
https://doaj.org/article/b65b38ee1c4240a09ec8b85afdab8a13
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, a
Externí odkaz:
https://doaj.org/article/beb20e0fa85c43b4b3d03df660ce8839