Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kab Seog Yoon"'
Publikováno v:
Synthetic Communications. 42:1890-1894
A diaryl isoxazole compound, KRIBB3, which exhibits strong antimigratory and antimitotic activities against cancer cells, was prepared in a practical synthetic way. The synthetic method may provide easy access to KRIBB3 analogs with various substitue
Autor:
Ki Deok Shin, Byoung-Mog Kwon, Jae Nyoung Kim, Ji Hye Min, Dong Cho Han, Sangku Lee, Kab Seog Yoon
Publikováno v:
Bulletin of the Korean Chemical Society. 31:3800-3802
Therefore, the development of can cer therapy targeted to cyto-toxicity is still important. Cell cycle control is the major regula-tory mechanism of cell growth. Small chemicals that inhibit cell cycle progression have attr acted much attention for c
Publikováno v:
BMB Reports. 38:763-765
A new simplified procedure for identifying human plasmin was developed using a DTT copolymerized agarose stacking gel (ASG) system. Agarose (1 %) was used for the stacking gel because DTT inhibits the polymerization of acrylamide. Human plasmin showe
Publikováno v:
ChemInform. 43
KRIBB3 (XI), which exhibits strong antimigratory and antimitotic activities against cancer cells, is prepared in a practical synthetic way.
Autor:
Ki Deok Shin, Ji Hye Min, Kab Seog Yoon, Sangku Lee, Dong Cho Han, Jae Nyoung Kim, Byoung-Mog Kwon
Publikováno v:
ChemInform. 42
Diarylisoxazole derivatives (VI), analogues of the strongly antimitotic compound KRIBB3, are synthesized and evaluated for their antiproliferative activity.
Autor:
Jae Nyoung Kim, Sangku Lee, Hyeong Kyu Lee, Dong Cho Han, Byoung-Mog Kwon, Ki Deok Shin, Kab Seog Yoon
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(3)
A series of KRIBB3 analogs were synthesized by modifying substituents at aryl moieties of KRIBB3 for examining structure-activity relationships, and their inhibitory activities on microtubule polymerization were evaluated. The presence of free phenol
Autor:
Keiji Miyazawa, Dong Cho Han, Jung Min Kim, Su-Hyung Hong, Su-Kyung Lee, Kwang-Hee Son, Jong Heum Park, Jina Kim, Byoung-Mog Kwon, Kab Seog Yoon
Publikováno v:
Life sciences. 78(19)
Non-steroidal anti-inflammatory drugs are known to be the most widely used drugs to exert their anti-inflammatory activities. It was examined protein expression profiles of human rheumatoid fibroblast-like synoviocyte MH7A cells treated with celecoxi
Publikováno v:
Journal of biochemistry and molecular biology. 37(3)
In general, a SYPRO Ruby dye is well known as a sensitive fluorescence-based method for detecting proteins by one-or two-dimensional SDS-PAGE (1-DE or 2-DE). Based on the SYPRO Ruby dye system, the combined two-dimensional fibrin zymography (2-D FZ)
Autor:
Kyoung Yoen Han, Seung Ho Kim, Nack Shick Choi, Kab Seog Yoon, Jin Young Lee, Byoung Young Kim
Publikováno v:
Journal of biochemistry and molecular biology. 35(2)
Based on the zymography analysis, Bacillus sp. DJ-4 (screened from Doen-Jang, a Korean traditional fermented food) secretes seven extracellular fibrinolytic enzymes (EFEs; 68, 64, 55, 45, 33, 27, and 13 kDa) in culture broth. These seven EFEs were an