Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kaari A, Lynch"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65664 (2013)
Generation of skin appendages in engineered skin substitutes has been limited by lack of trichogenic potency in cultured postnatal cells. To investigate the feasibility and the limitation of hair regeneration, engineered skin substitutes were prepare
Externí odkaz:
https://doaj.org/article/e62437f2037748f89138c08cb03c87cf
Autor:
Ze Jiang, Kaari A. Lynch, Yaping Huai, Ross Zafonte, Yao Wang, Qing Mei Wang, James K. Liao, Lisa Wood, Shanshan Li
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 97:492-499
Objectives Cognitive dysfunction and dementia are common following ischemic stroke. Endothelial nitric oxide synthase (eNOS) has been found to play an important role in neurologic function and cognition. The purpose of the present study was to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326383f65c3d378d81fa82bed4aaa7ef
https://doi.org/10.1097/phm.0000000000000904
https://doi.org/10.1097/phm.0000000000000904
Cytotoxic chemotherapy can induce a systemic inflammatory response which has been proposed to be an underlying mechanism of cancer treatment related fatigue. Dexamethasone, a synthetic glucocorticoid that has potent anti-inflammatory effects, is inco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7e30bc74d00f9f87d6796e5790da82
https://europepmc.org/articles/PMC5790388/
https://europepmc.org/articles/PMC5790388/
Autor:
Belinda H. Dickie, Kathryn Glaser, Alexander J. Osborn, Kaari A. Lynch, Derek E. Neilson, Anita Gupta, Peter Dickie
Publikováno v:
Human Molecular Genetics. 24:926-938
Lymphatic malformations (LMs) are developmental anomalies of the lymphatic system associated with the dysmorphogenesis of vascular channels lined by lymphatic endothelial cells (LECs). Seeking to identify intrinsic defects in affected LECs, cells wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b15fb5b6efeb636159173aea28ef51b
https://doi.org/10.1093/hmg/ddu505
https://doi.org/10.1093/hmg/ddu505
Autor:
Tetsuya Okada, Jeffrey Robbins, Jeffrey M. Lynch, Ron Prywes, Kaari A. Lynch, Davy Vanhoutte, Michelle A. Sargent, Jack Lawler, Kazutoshi Mori, Aryn Schloemer, Hanna Osinska, Jeffery D. Molkentin, N. Scott Blair, Bruce J. Aronow, John N. Lorenz, Marjorie Maillet
Publikováno v:
Cell. 149:1257-1268
Thrombospondin (Thbs) proteins are induced in sites of tissue damage or active remodeling. The endoplasmic reticulum (ER) stress response is also prominently induced with disease where it regulates protein production and resolution of misfolded prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b7055fc34c7186b40c7c622a5779d4
https://doi.org/10.1016/j.cell.2012.03.050
https://doi.org/10.1016/j.cell.2012.03.050
Autor:
Kaari A. Lynch, Elizabeth A. Maier, Dorothy M. Supp, Jennifer M. Hahn, Steven T. Boyce, Penkanok Sriwiriyanont
Publikováno v:
Experimental Dermatology. 21:783-785
Engineered skin substitutes (ESS) have been used successfully to treat life-threatening burns, but lack cutaneous appendages. To address this deficiency, dermal constructs were prepared using collagen-glycosaminoglycan scaffolds populated with murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5faeb4bfb29da54dfa12670070d7c115
https://doi.org/10.1111/exd.12003
https://doi.org/10.1111/exd.12003
Publikováno v:
Journal of Biomechanical Engineering. 136
Engineered skin substitutes (ESSs) have been reported to close full-thickness burn wounds but are subject to loss from mechanical shear due to their deficiencies in tensile strength and elasticity. Hypothetically, if the mechanical properties of ESS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607fcd780b3c382683f489e122aacb6c
https://doi.org/10.1115/1.4026290
https://doi.org/10.1115/1.4026290
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65664 (2013)
PLoS ONE, Vol 8, Iss 6, p e65664 (2013)
Generation of skin appendages in engineered skin substitutes has been limited by lack of trichogenic potency in cultured postnatal cells. To investigate the feasibility and the limitation of hair regeneration, engineered skin substitutes were prepare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5273f26b586eb5adf9b41747b83be32d
https://pubmed.ncbi.nlm.nih.gov/23799033
https://pubmed.ncbi.nlm.nih.gov/23799033
Autor:
Andrew P. Supp, Steven T. Boyce, Dorothy M. Supp, Viki B. Swope, Rachel K. Rice, Kaari A. Lynch, Richard J. Kagan
Publikováno v:
Wound Repair and Regeneration.
Stable closure of skin wounds with engineered skin substitutes (ESS) requires indefinite mitotic capacity to generate the epidermis. To evaluate whether keratinocytes in ESS exhibit the stem cell phenotype of label retention, ESS (n = 6-9/group) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3d60904ba18e00d563ea6aff1a765a
https://doi.org/10.1111/j.1524-475x.2012.00807.x
https://doi.org/10.1111/j.1524-475x.2012.00807.x
Autor:
Steven T, Boyce, Rachel K, Rice, Kaari A, Lynch, Andrew P, Supp, Viki B, Swope, Richard J, Kagan, Dorothy M, Supp
Publikováno v:
Wound Repair Regen
Stable closure of skin wounds with engineered skin substitutes (ESS) requires indefinite mitotic capacity to generate the epidermis. To evaluate whether keratinocytes in ESS exhibit the stem cell phenotype of label retention, ESS (n = 6–9/group) we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3f2095beaca1fab648d447ce8396c79
https://pubmed.ncbi.nlm.nih.gov/22672265
https://pubmed.ncbi.nlm.nih.gov/22672265