Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Kaarel Krjutskov"'
Autor:
Alvin Meltsov, Merli Saare, Hindrek Teder, Priit Paluoja, Riikka K. Arffman, Terhi Piltonen, Piotr Laudanski, Mirosław Wielgoś, Luca Gianaroli, Mariann Koel, Maire Peters, Andres Salumets, Kaarel Krjutškov, Priit Palta
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Expressional profiling of the endometrium enables the personalised timing of the window of implantation (WOI). This study presents and evaluates a novel analytical pipeline based on a TAC-seq (Targeted Allele Counting by sequencing) method f
Externí odkaz:
https://doaj.org/article/5fb92c738fde4f878dd96a1928826e5a
Autor:
Nina Boskovic, Gamze Yazgeldi, Sini Ezer, Mari H. Tervaniemi, Jose Inzunza, Spyridon Panagiotis Deligiannis, Barış Yaşar, Tiina Skoog, Kaarel Krjutškov, Shintaro Katayama, Juha Kere
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102357- (2023)
Summary: Here, we present a modification of single-cell tagged reverse transcription protocol to study gene expression on a single-cell level or with limited RNA input. We describe different enzymes for reverse transcription and cDNA amplification, m
Externí odkaz:
https://doaj.org/article/7ccf6d4dcc9247fbbbca7ff5b1e36e3b
Autor:
Sanna Vuoristo, Shruti Bhagat, Christel Hydén-Granskog, Masahito Yoshihara, Lisa Gawriyski, Eeva-Mari Jouhilahti, Vipin Ranga, Mahlet Tamirat, Mikko Huhtala, Ida Kirjanov, Sonja Nykänen, Kaarel Krjutškov, Anastassius Damdimopoulos, Jere Weltner, Kosuke Hashimoto, Gaëlle Recher, Sini Ezer, Priit Paluoja, Pauliina Paloviita, Yujiro Takegami, Ai Kanemaru, Karolina Lundin, Tomi T. Airenne, Timo Otonkoski, Juha S. Tapanainen, Hideya Kawaji, Yasuhiro Murakawa, Thomas R. Bürglin, Markku Varjosalo, Mark S. Johnson, Timo Tuuri, Shintaro Katayama, Juha Kere
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104137- (2022)
Summary: Double homeobox 4 (DUX4) is expressed at the early pre-implantation stage in human embryos. Here we show that induced human DUX4 expression substantially alters the chromatin accessibility of non-coding DNA and activates thousands of newly i
Externí odkaz:
https://doaj.org/article/e20d78e8cdab451083fb4b3f94c08b7f
Autor:
Shintaro Katayama, Tiina Skoog, Cilla Söderhäll, Elisabet Einarsdottir, Kaarel Krjutškov, Juha Kere
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Standard RNAseq methods using bulk RNA and recent single-cell RNAseq methods use DNA barcodes to identify samples and cells, and the barcoded cDNAs are pooled into a library pool before high throughput sequencing. In cases of sing
Externí odkaz:
https://doaj.org/article/043e8dac8a1a436db127b1c2770db1c5
Autor:
Elisabet Einarsdottir, Minna Pekkinen, Kaarel Krjutškov, Shintaro Katayama, Juha Kere, Outi Mäkitie, Heli Viljakainen
Publikováno v:
Endocrine Connections, Vol 8, Iss 5, Pp 559-570 (2019)
Objective: The effect of vitamin D at the transcriptome level is poorly understood, and furthermore, it is unclear if it differs between obese and normal-weight subjects. The objective of the study was to explore the transcriptome effects of vitamin
Externí odkaz:
https://doaj.org/article/3c0c7d5a02e64632a6ad5d4f020333ca
Autor:
Jelena Štšepetova, Jaak Truu, Riina Runnel, Rita Nõmmela, Mare Saag, Jana Olak, Hiie Nõlvak, Jens-Konrad Preem, Kristjan Oopkaup, Kaarel Krjutškov, Eino Honkala, Sisko Honkala, Kauko Mäkinen, Pirkko-Liisa Mäkinen, Tero Vahlberg, Joan Vermeiren, Douwina Bosscher, Peter de Cock, Reet Mändar
Publikováno v:
BMC Oral Health, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Oral microbiome has significant impact on both oral and general health. Polyols have been promoted as sugar substitutes in prevention of oral diseases. We aimed to reveal the effect of candies containing erythritol, xylitol or con
Externí odkaz:
https://doaj.org/article/07db41cabe174b239aedf4abca29fd75
Autor:
Anna M.L. Coenen-Stass, Helena Sork, Sole Gatto, Caroline Godfrey, Amarjit Bhomra, Kaarel Krjutškov, Jonathan R. Hart, Jakub O. Westholm, Liz O’Donovan, Andreas Roos, Hanns Lochmüller, Pier Lorenzo Puri, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 1-15 (2018)
Extracellular small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for diseases such as Duchenne muscular dystrophy (DMD), although their biological relevance is largely unknown. To investigate the relationship between intracell
Externí odkaz:
https://doaj.org/article/dc55244590fd44329400bbee0db3a420
Publikováno v:
Frontiers in Plant Science, Vol 11 (2020)
Fast and reliable analytical methods for the identification of plants from metagenomic samples play an important role in identifying the components of complex mixtures of processed biological materials, including food, herbal products, gut contents o
Externí odkaz:
https://doaj.org/article/b84886fc8f4b488eb150cb894ba78e6a
Autor:
Inken Körber, Shintaro Katayama, Elisabet Einarsdottir, Kaarel Krjutškov, Paula Hakala, Juha Kere, Anna-Elina Lehesjoki, Tarja Joensuu
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158195 (2016)
Progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1, OMIM254800) is an autosomal recessive neurodegenerative disorder characterized by stimulus-sensitive and action-activated myoclonus, tonic-clonic epileptic seizures, and ataxia. Loss-o
Externí odkaz:
https://doaj.org/article/46c5d0206a694f7ea2830b653dc18db8
Autor:
Sini Ezer, Masahito Yoshihara, Shintaro Katayama, Carsten Daub, Hannes Lohi, Kaarel Krjutskov, Juha Kere
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100995- (2021)
Summary: We have developed a protocol for barcoded cDNA libraries of 48 samples to study gene expression across tissues in the domestic dog, Canis familiaris, by modifying the Single-Cell Tagged Reverse Transcription (STRT) protocol (Islam et al., 20
Externí odkaz:
https://doaj.org/article/d4999bfde08e446a941caa5a98b91b2b