Zobrazeno 1 - 10
of 819
pro vyhledávání: '"Kaare M"'
Autor:
Carolina Medina-Gomez, Benjamin H. Mullin, Alessandra Chesi, Vid Prijatelj, John P. Kemp, Chen Shochat-Carvalho, Katerina Trajanoska, Carol Wang, Raimo Joro, Tavia E. Evans, Katharina E. Schraut, Ruifang Li-Gao, Tarunveer S. Ahluwalia, M. Carola Zillikens, Kun Zhu, Dennis O. Mook-Kanamori, Daniel S. Evans, Maria Nethander, Maria J. Knol, Gudmar Thorleifsson, Ivana Prokic, Babette Zemel, Linda Broer, Fiona E. McGuigan, Natasja M. van Schoor, Sjur Reppe, Mikolaj A. Pawlak, Stuart H. Ralston, Nathalie van der Velde, Mattias Lorentzon, Kari Stefansson, Hieab H. H. Adams, Scott G. Wilson, M. Arfan Ikram, John P. Walsh, Timo A. Lakka, Kaare M. Gautvik, James F. Wilson, Eric S. Orwoll, Cornelia M. van Duijn, Klaus Bønnelykke, Andre G. Uitterlinden, Unnur Styrkársdóttir, Kristina E. Akesson, Timothy D. Spector, Jonathan H. Tobias, Claes Ohlsson, Janine F. Felix, Hans Bisgaard, Struan F. A. Grant, J. Brent Richards, David M. Evans, Bram van der Eerden, Jeroen van de Peppel, Cheryl Ackert-Bicknell, David Karasik, Erika Kague, Fernando Rivadeneira
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Skull bone mineral density (SK-BMD) provides a suitable trait for the discovery of key genes in bone biology, particularly to intramembranous ossification, not captured at other skeletal sites. We perform a genome-wide association meta-analy
Externí odkaz:
https://doaj.org/article/48a29b7a20594248bc9b5e7eb32dd872
Autor:
Kaare M. Gautvik, Daniel Sachse, Alexandra C. Hinton, Ole K. Olstad, Douglas P. Kiel, Yi-Hsiang Hsu, Tor P. Utheim, Christine W. Lary, Sjur Reppe
Publikováno v:
BMC Genomic Data, Vol 23, Iss 1, Pp 1-6 (2022)
Abstract Background Physical molecular interactions are the basis of intracellular signalling and gene regulatory networks, and comprehensive, accessible databases are needed for their discovery. Highly correlated transcripts may reflect important fu
Externí odkaz:
https://doaj.org/article/b6fee24839894841a8bd818e1d58c5b1
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
This study presents skeletal material from five medieval burial sites in Eastern Norway, confined to one royal burial church, one Dominican monastery, and three burial sites representing parish populations. We combine osteological analysis and Dual E
Externí odkaz:
https://doaj.org/article/10efb04ce38b4dcf918b5f15cb8c05ee
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101059- (2021)
Purpose: Lipocalin 2 (LCN2) is an adipokine involved in many physiological functions, including bone metabolism. We previously demonstrated its implication in mouse models of mechanical unloading-induced osteoporosis and in a cohort of bed rest volun
Externí odkaz:
https://doaj.org/article/4cf324de3c2c4a8aa2eefdc170920629
Autor:
Vid Prijatelj, Sjur Reppe, Matthew Dietz, Carolina M. Medina-Gomez, Joost A. Verlouw, Andre J. van Wijnen, Kaare M. Gautvik, Eppo B. Wolvius, Fernando Rivadeneira
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100501- (2020)
Externí odkaz:
https://doaj.org/article/f28eec54168c48228873e97649ab4ffd
Autor:
Vid Prijatelj, Sjur Reppe, Matthew Dietz, Carolina M. Medina-Gomez, Joost A. Verlouw, Cindy G. Boer, Joyce B.J. van Meurs, Andre J. van Wijnen, Kaare M. Gautvik, Eppo B. Wolvius, Fernando Rivadeneira
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100503- (2020)
Externí odkaz:
https://doaj.org/article/d42a5dd149924b408d46cfa205363f37
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
Autor:
Sjur Reppe, Tonje G. Lien, Yi-Hsiang Hsu, Vigdis T. Gautvik, Ole K. Olstad, Rona Yu, Hege G. Bakke, Robert Lyle, Marianne K. Kringen, Ingrid K. Glad, Kaare M. Gautvik
Publikováno v:
Epigenetics, Vol 12, Iss 8, Pp 674-687 (2017)
DNA methylation affects expression of associated genes and may contribute to the missing genetic effects from genome-wide association studies of osteoporosis. To improve insight into the mechanisms of postmenopausal osteoporosis, we combined transcri
Externí odkaz:
https://doaj.org/article/122bdce6868d4632b3931a2a8da889fb
Autor:
Carolina Medina-Gomez, John P. Kemp, Niki L. Dimou, Eskil Kreiner, Alessandra Chesi, Babette S. Zemel, Klaus Bønnelykke, Cindy G. Boer, Tarunveer S. Ahluwalia, Hans Bisgaard, Evangelos Evangelou, Denise H. M. Heppe, Lynda F. Bonewald, Jeffrey P. Gorski, Mohsen Ghanbari, Serkalem Demissie, Gustavo Duque, Matthew T. Maurano, Douglas P. Kiel, Yi-Hsiang Hsu, Bram C.J. van der Eerden, Cheryl Ackert-Bicknell, Sjur Reppe, Kaare M. Gautvik, Truls Raastad, David Karasik, Jeroen van de Peppel, Vincent W. V. Jaddoe, André G. Uitterlinden, Jonathan H. Tobias, Struan F.A. Grant, Pantelis G. Bagos, David M. Evans, Fernando Rivadeneira
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Author summary Bone mineral density and lean skeletal mass are heritable traits. Here, Medina-Gomez and colleagues perform bivariate GWAS analyses of total body lean mass and bone mass density in children, and show genetic loci with pleiotropic effec
Externí odkaz:
https://doaj.org/article/c29862cdbe2e426d82346b87b13a5d6e
Autor:
Sara Domingues, Natasha Rosário, Ângela Cândido, Daniela Neto, Kaare M. Nielsen, Gabriela J. Da Silva
Publikováno v:
Microorganisms, Vol 7, Iss 2, p 30 (2019)
Horizontal gene transfer events provide the basis for extensive dissemination of antimicrobial resistance traits between bacterial populations. Conjugation is considered to be the most frequent mechanism behind new resistance acquisitions in clinical
Externí odkaz:
https://doaj.org/article/0956f1ad3978434cbe9b726eca1a37eb
Autor:
Sjur Reppe, Yunpeng Wang, Wesley K Thompson, Linda K McEvoy, Andrew J Schork, Verena Zuber, Marissa LeBlanc, Francesco Bettella, Ian G Mills, Rahul S Desikan, Srdjan Djurovic, Kaare M Gautvik, Anders M Dale, Ole A Andreassen, GEFOS Consortium
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144531 (2015)
Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the sugg
Externí odkaz:
https://doaj.org/article/9a6faae547154700a766db86778b49e1