Zobrazeno 1 - 10
of 31
pro vyhledávání: '"KaWah Li"'
Autor:
Mary Aderayo Bamimore, Jeanine E. Roeters van Lennep, Giuliana Fortunato, Vasiliki Mollaki, Eran Leitersdorf, Antonietta D'Angelo, Sonia Shah, Euridiki Drogari, Philippa J. Talmud, Steve E. Humphries, Albert Wiegman, Mahtab Sharifi, Małgorzata Waluś-Miarka, Maria Nicoletta D'Agostino, KaWah Li, Paolo Rubba, Monique T. Mulder, Ros Whittall, Jackie A. Cooper, Ronen Durst, Marta Futema, Olivia Goldberg, Robert A. Hegele, Eric J.G. Sijbrands, Joep C. Defesche, John C. Whittaker
Publikováno v:
Clinical Chemistry, 61(1), 231-238. American Association for Clinical Chemistry Inc.
Clinical chemistry, 61(1), 231-238. American Association for Clinical Chemistry Inc.
Clinical chemistry, 61(1), 231-238. American Association for Clinical Chemistry Inc.
BACKGROUND Familial hypercholesterolemia (FH) is an autosomal-dominant disorder caused by mutations in 1 of 3 genes. In the 60% of patients who are mutation negative, we have recently shown that the clinical phenotype can be associated with an accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b4d47d19b710c509d83e586b9ccd15
https://doi.org/10.1373/clinchem.2014.231365
https://doi.org/10.1373/clinchem.2014.231365
Autor:
Handrean Soran, KaWah Li, Devaki Nair, Frank M. van Bockxmeer, Fredrik Karpe, H. Andrew W. Neil, Robert A. Hegele, Sebastiano Calandra, Olivier S. Descamps, Mary Seed, Marta Futema, Vincent Plagnol, Nicholas Lench, Steve E. Humphries, Stefano Bertolini, Eran Leitersdorf, Ronen Durst, Ros Whittall, Colin A. Graham
Publikováno v:
Journal of Medical Genetics
BACKGROUND: Familial hypercholesterolaemia (FH) is an autosomal dominant disease of lipid metabolism, which leads to early coronary heart disease. Mutations in LDLR, APOB and PCSK9 can be detected in 80% of definite FH (DFH) patients. This study aime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149d71d0acef8e71fdd85fa3ef58538
https://doi.org/10.1136/jmedgenet-2014-102405
https://doi.org/10.1136/jmedgenet-2014-102405
Autor:
Victoria M. Meyrick, Hugh Montgomery, Bhavin Mehta, Kawah Li, Nicholas S Hopkinson, Katrina J. Curtis, William D.-C. Man, Gulam S. Haji, Michael I. Polkey
Epidemiological studies in older individuals have found an association between the use of angiotensin-converting enzyme (ACE) inhibition (ACE-I) therapy and preserved locomotor muscle mass, strength, and walking speed. ACE-I therapy might therefore h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a954e86db2923f07f12bc0c230dfa9
https://europepmc.org/articles/PMC5148142/
https://europepmc.org/articles/PMC5148142/
Autor:
Katherine E, Beaney, Claire E, Ward, Dauda A S, Bappa, Nadine, McGale, Anna K, Davies, Shashivadan P, Hirani, KaWah, Li, Philip, Howard, Dwaine R, Vance, Martin A, Crockard, John V, Lamont, Stanton, Newman, Steve E, Humphries
Publikováno v:
Cardiovascular Diabetology
Background The coronary risk in diabetes (CoRDia) trial (n = 211) compares the effectiveness of usual diabetes care with a self-management intervention (SMI), with and without personalised risk information (including genetics), on clinical and behavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33ce4e98d7ce1a65bea6c2795445998e
https://pubmed.ncbi.nlm.nih.gov/27716211
https://pubmed.ncbi.nlm.nih.gov/27716211
Autor:
Christina Hubbart, George Dedoussis, M Scartezini, Steve E. Humphries, R. Whittall, KaWah Li, Z Reiner, H. A. W. Neil, A Abraha
Aims Current screening methods, such as single strand conformational polymorphism (SSCP) and denaturing high performance liquid chromatography (dHPLC) that are used for detecting mutations in familial hypercholesterolaemia (FH) subjects are time cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bf8e38240356c352122a6fd64b4d82
https://ora.ox.ac.uk/objects/uuid:a1909100-d674-4b4c-bc72-0bf8ceb688b9
https://ora.ox.ac.uk/objects/uuid:a1909100-d674-4b4c-bc72-0bf8ceb688b9
Autor:
KaWah Li, Jackie A. Cooper, Abdul Rehman, Katherine E. Beaney, Shabana ᅟ, Stephen E. Humphries, Saleem Ullah Shahid
Publikováno v:
Lipids in Health and Disease
Background Many SNPs have been identified in genes regulating LDL-C metabolism, but whether their influence is similar in subjects from different ethnicities is unclear. Effect of 4 such SNPs on LDL-C and coronary heart disease (CHD) was examined in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a1c1ff73edaed5efb0be4017339cdb
https://doi.org/10.1186/s12944-016-0253-0
https://doi.org/10.1186/s12944-016-0253-0
Autor:
Shahid, Saleem, Shabana á , Cooper, Jackie, Beaney, Katherine, Kawah Li, Rehman, Abdul, Humphries, Stephen
Comparison of RAFs between Pakistani and NPHSII study groups. (DOC 31 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc97810963e627adecc681ba246b920
Autor:
Shahid, Saleem, Shabana á , Cooper, Jackie, Beaney, Katherine, Kawah Li, Rehman, Abdul, Humphries, Stephen
Box plot showing the distribution of gene score in non CHD and CHD subjects and its association with LDL-C in Pakistani people. The figure shows the distribution of gene score in Pakistani CHD and non CHD. It is clear that the gene score is high in C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303fd9ed9c999d40fc449c2951e0bb37
Autor:
Shahid, Saleem, Shabana á , Cooper, Jackie, Beaney, Katherine, Kawah Li, Rehman, Abdul, Humphries, Stephen
Basic features of SNPs under study. (DOC 33 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9549654caae70bb2a4cf54b8a708be41
Autor:
Shahid, Saleem, Shabana á , Cooper, Jackie, Beaney, Katherine, Kawah Li, Rehman, Abdul, Humphries, Stephen
Mean LDL-C by number of LDL-C raising SNPs for the unweighted gene score. (DOC 37 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb96275ccbd0d5197c56a692b4b6173