Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ka-Wai Sun"'
Autor:
Ka-Wai Sun, Antonia A. Nemec, Veronika Northrup, Katherine A. Donigan, Xiangyu Cong, Drew L. Murphy, Joann B. Sweasy, Daniel Zelterman
Previous small scale sequencing studies have indicated that DNA polymerase β (pol β) variants are present on average in 30% of human tumors of varying tissue origin. Many of these variants have been shown to have aberrant enzyme function in vitro a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792fa3b7697c8ece1f8c68411bd8052f
https://europepmc.org/articles/PMC3390656/
https://europepmc.org/articles/PMC3390656/
Autor:
Joann B. Sweasy, Suzanne Hile, Ka Wai Sun, Daniela Starcevic, Shibani Dalal, Kristin A. Eckert
Publikováno v:
Biochemistry. 44(48)
Studies show that 30% of 189 tumors sequenced to date express variants of the polymerase beta (pol beta) protein that are not present in normal tissue. This raises the possibility that variants of pol beta might be linked to the etiology of cancer. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc48b3800afdce24b643952842d9a541
https://pubmed.ncbi.nlm.nih.gov/16313169
https://pubmed.ncbi.nlm.nih.gov/16313169
Autor:
Shibani Dalal, Char-Chang Lai, Daniel DiMaio, Joann B. Sweasy, Ka-Wai Sun, Daniela Starcevic, Tieming Lang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(40)
Thirty percent of the 189 tumors studied to date express DNA polymerase β variants. One of these variants was identified in a prostate carcinoma and is altered from isoleucine to methionine at position 260, within the hydrophobic hinge region of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efc706868632a7a11d547bbb9ffffd0
https://pubmed.ncbi.nlm.nih.gov/16179390
https://pubmed.ncbi.nlm.nih.gov/16179390
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(17)
DNA polymerase β functions in both base excision repair and meiosis. Errors committed by polymerase β during these processes could result in mutations. Using a complementation system, in which rat DNA polymerase β substitutes for DNA polymerase I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a682b70eb13fb9a2be58b15675b24684
https://pubmed.ncbi.nlm.nih.gov/10449735
https://pubmed.ncbi.nlm.nih.gov/10449735
Autor:
Donigan, Katherine A.1, Ka-wai Sun1, Nemec, Antonia A.1, Murphy, Drew L.1, Xiangyu Cong2, Northrup, Veronika2, Zelterman, Daniel2, Sweasy, Joann B.1 joann.sweasy@yale.edu
Publikováno v:
Journal of Biological Chemistry. 7/6/2012, Vol. 287 Issue 28, p23830-23839. 10p.
Autor:
Sweasy, Joann B., Tieming Lang, Starcevic, Daniela, Ka-Wai Sun, Char-Chang Lai, DiMaio, Daniel, Dalal, Shibani, Hanawalt, Philip C.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/4/2005, Vol. 102 Issue 40, p14350-14355, 6p