Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ka-Cheung Luk"'
Autor:
Ka-Cheung Luk, Jeffrey Gersch, Barbara J. Harris, Vera Holzmayer, Dora Mbanya, Silvia Sauleda, Mary A. Rodgers, Gavin Cloherty
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract HBV produces unspliced and spliced RNAs during replication. Encapsidated spliced RNA is converted into DNA generating defective virions that are detected in plasma and associated with HCC development. Herein we describe a quantitative real-t
Externí odkaz:
https://doaj.org/article/b698668b33264645924fce0e1da59735
Development and performance of prototype serologic and molecular tests for hepatitis delta infection
Autor:
Kelly E. Coller, Emily K. Butler, Ka-Cheung Luk, Mary A. Rodgers, Michael Cassidy, Jeffrey Gersch, Anne L. McNamara, Mary C. Kuhns, George J. Dawson, Lazare Kaptue, Birgit Bremer, Heiner Wedemeyer, Gavin A. Cloherty
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Worldwide, an estimated 5% of hepatitis B virus (HBV) infected people are coinfected with hepatitis delta virus (HDV). HDV infection leads to increased mortality over HBV mono-infection, yet HDV diagnostics are not widely available. Prototyp
Externí odkaz:
https://doaj.org/article/cecdf5f3f90443218de37d948b89f5d9
Autor:
Michael G. Berg, Kenn Forberg, Lester J. Perez, Ka-Cheung Luk, Todd V. Meyer, Gavin A. Cloherty
Publikováno v:
Viruses, Vol 13, Iss 12, p 2534 (2021)
Picobirnaviruses (PBV) are found in a wide range of hosts and typically associated with gastrointestinal infections in immunocompromised individuals. Here, a divergent PBV genome was assembled from a patient hospitalized for acute respiratory illness
Externí odkaz:
https://doaj.org/article/7ce35e74c59744b6bc524166ba209d0b
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203618 (2018)
Hepatitis E virus (HEV) is a viral pathogen transmitted by the fecal-oral route and is a major cause of waterborne acute hepatitis in many developing countries. In addition to infecting humans, HEV has been identified in swine, wild boars, rabbits an
Externí odkaz:
https://doaj.org/article/44c9944fa7a4464db76dd6c85bca81e6
Autor:
Ka-Cheung Luk, Michael G Berg, Samia N Naccache, Beniwende Kabre, Scot Federman, Dora Mbanya, Lazare Kaptué, Charles Y Chiu, Catherine A Brennan, John Hackett
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141723 (2015)
Given the dynamic changes in HIV-1 complexity and diversity, next-generation sequencing (NGS) has the potential to revolutionize strategies for effective HIV global surveillance. In this study, we explore the utility of metagenomic NGS to characteriz
Externí odkaz:
https://doaj.org/article/cc2e10d5fb584d51a29731fe14c6c229
Autor:
Deanna Lee, Jaydip Das Gupta, Christina Gaughan, Imke Steffen, Ning Tang, Ka-Cheung Luk, Xiaoxing Qiu, Anatoly Urisman, Nicole Fischer, Ross Molinaro, Miranda Broz, Gerald Schochetman, Eric A Klein, Don Ganem, Joseph L Derisi, Graham Simmons, John Hackett, Robert H Silverman, Charles Y Chiu
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44954 (2012)
XMRV, or xenotropic murine leukemia virus (MLV)-related virus, is a novel gammaretrovirus originally identified in studies that analyzed tissue from prostate cancer patients in 2006 and blood from patients with chronic fatigue syndrome (CFS) in 2009.
Externí odkaz:
https://doaj.org/article/cc0eca477cbf493faa628dcd60a4f7d2
Autor:
Jaydip Das Gupta, Ka-Cheung Luk, Ning Tang, Christina Gaughan, Eric A Klein, Eugene S Kandel, John Hackett, Robert H Silverman
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36072 (2012)
The 22Rv1 cell line is widely used for prostate cancer research and other studies throughout the world. These cells were established from a human prostate tumor, CWR22, that was serially passaged in nude mice and selected for androgen independence. T
Externí odkaz:
https://doaj.org/article/34a48babc6344e4888714ef9eedeba40
Autor:
Gregory S Orf, Lester J Perez, Todd V Meyer, Ka-Cheung Luk, Kenn Forberg, Mary A Rodgers, Abbas Hadji, Linda James, Samuel Mampunza, Asmeeta Achari, Guixia Yu, Scot Federman, Charles Y Chiu, Carole A McArthur, Gavin A Cloherty, Michael G Berg
Publikováno v:
Virus evolution, vol 9, iss 1
Pathogens carried by insects, such as bunyaviruses, are frequently transmitted into human populations and cause diseases. Knowing which spillover events represent a public health threat remains a challenge. Metagenomic next-generation sequencing (mNG
Autor:
Mary C. Kuhns, Maria De Medina, Jeffrey Gersch, Eugene R. Schiff, Vera Holzmayer, Gavin Cloherty, Anne L. McNamara, Ka Cheung Luk, Emily K. Butler
Publikováno v:
Hepatology. 68:2106-2117
Treatment of chronic hepatitis B (CHB) patients with nucleos(t)ide analogs (NAs) suppresses hepatitis B virus (HBV) DNA synthesis but does not affect synthesis of HBV pregenomic RNA (pgRNA). Hepatitis B virus pgRNA is detectable in the serum during N
Autor:
Michael Cassidy, Kelly E. Coller, Heiner Wedemeyer, Emily K. Butler, Jeffrey Gersch, Mary C. Kuhns, Gavin Cloherty, Ka-Cheung Luk, Anne L. McNamara, Lazare Kaptue, Birgit Bremer, George J. Dawson, Mary A. Rodgers
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.