Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ka-Cheuk Liu"'
Autor:
Ka-Cheuk Liu, Alethia Villasenor, Maria Bertuzzi, Nicole Schmitner, Niki Radros, Linn Rautio, Kenny Mattonet, Ryota L Matsuoka, Sven Reischauer, Didier YR Stainier, Olov Andersson
Publikováno v:
eLife, Vol 10 (2021)
To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into the avascular npas4l mutant (i.e. cloche). Surprisingly, β-cell regeneration increased markedly in npas4l mutants owing
Externí odkaz:
https://doaj.org/article/5fcefc8ad85f405783b16d404e47a553
Autor:
Nadja Schulz, Ka-Cheuk Liu, Jérémie Charbord, Charlotte L. Mattsson, Lingjie Tao, Dominika Tworus, Olov Andersson
Publikováno v:
Molecular Metabolism, Vol 5, Iss 11, Pp 1138-1146 (2016)
Objective: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating
Externí odkaz:
https://doaj.org/article/9534a2d0becc4097ab5b790f52b06eb4
Autor:
Ka-Cheuk Liu, Wei Ge
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62524 (2013)
Estradiol (E2) stimulates luteinizing hormone receptor (lhcgr) expression in zebrafish follicle cells via nuclear estrogen receptors (nERs) that are likely expressed on the membrane, and lhcgr responds to E2 in a biphasic manner during 24-h treatment
Externí odkaz:
https://doaj.org/article/7c81ec71e335460c81315590feb9ed4a
Autor:
Lianhe Chu, Michishige Terasaki, Charlotte L. Mattsson, Romain Teinturier, Jérémie Charbord, Ercument Dirice, Ka-Cheuk Liu, Michael G. Miskelly, Qiao Zhou, Nils Wierup, Rohit N. Kulkarni, Olov Andersson
Publikováno v:
Cell Chemical Biology. 29:1368-1380.e5
Analogs of the incretin hormones Gip and Glp-1 are used to treat type 2 diabetes and obesity. Findings in experimental models suggest that manipulating several hormones simultaneously may be more effective. To identify small molecules that increase t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa342366b22b0906a34ffb0e99120de
https://doi.org/10.1016/j.chembiol.2022.08.001
https://doi.org/10.1016/j.chembiol.2022.08.001
Autor:
Alethia Villasenor, Ryota L. Matsuoka, Linn Rautio, Olov Andersson, Nicole Schmitner, Didier Y.R. Stainier, Sven Reischauer, Maria Bertuzzi, Kenny Mattonet, Ka-Cheuk Liu, Niki Radros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47be09b0665d74da255e14718b9c9d9c
https://doi.org/10.7554/elife.65758.sa2
https://doi.org/10.7554/elife.65758.sa2
Autor:
Didier Y.R. Stainier, Alethia Villasenor, Olov Andersson, Niki Radros, Ka-Cheuk Liu, Sven Reischauer, Linn Rautio, Nicole Schmitner
To investigate the role of the vasculature in pancreatic β-cell regeneration, we crossed a zebrafish β-cell ablation model into the avascularnpas4lmutant (i.e.cloche). Surprisingly, β-cell regeneration increased markedly innpas4lmutants owing to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8a142e4e1dc96379a3283e0c1e75bb0
https://doi.org/10.1101/2021.02.01.429189
https://doi.org/10.1101/2021.02.01.429189
Publikováno v:
General and Comparative Endocrinology. 246:218-225
Estradiol (E2) stimulates luteinizing hormone receptor (lhcgr) expression via nuclear estrogen receptors (nERs) in the zebrafish ovary. We have demonstrated that endocrine hormones such as gonadotropin (hCG) and paracrine factors such as epidermal gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5ae168ba2890ffc650f6554f9638d2
https://doi.org/10.1016/j.ygcen.2016.12.011
https://doi.org/10.1016/j.ygcen.2016.12.011
Autor:
Olov Andersson, Bridget K. Wagner, Rohit N. Kulkarni, Ka-Cheuk Liu, Amedeo Vetere, Giorgio Basile, Jiang Hu
Publikováno v:
Diabetes. 68
Pancreatic elastase (PE) is a serine protease produced by pancreatic acinar cells. PE is mainly secreted in the intestine during digestion, and is also detectable in stromal pancreatic tissue, including the ECM of islets. Recently, we identified serp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af0be35c9ab840fc7ec578a29b2750fb
https://doi.org/10.2337/db19-111-or
https://doi.org/10.2337/db19-111-or
Autor:
Lingjie Tao, Jérémie Charbord, Olov Andersson, Nadja Schulz, Charlotte L. Mattsson, Ka-Cheuk Liu, Dominika Tworus
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 5, Iss 11, Pp 1138-1146 (2016)
Molecular Metabolism, Vol 5, Iss 11, Pp 1138-1146 (2016)
Objective Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86009f8c4682feb0272a2b039e4f4bd6
http://europepmc.org/articles/PMC5081418
http://europepmc.org/articles/PMC5081418
Autor:
Kerstin Brismar, Philippe Bertolino, Nadja Schulz, Jérémie Charbord, Olov Andersson, Ka-Cheuk Liu, Jing Lu, Christos Karampelias, Claes-Göran Östenson, Agneta Hilding, Linn Rautio
Publikováno v:
The EMBO Journal
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in people with diabetes. By performing whole‐genome expression profiling of zebrafish islets, we identified 11 secreted prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb376c68d7da7575020a501909a11dd
http://europepmc.org/articles/PMC5116948
http://europepmc.org/articles/PMC5116948