Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ka Ming, Nip"'
Autor:
Ka Ming Nip, Saber Hafezqorani, Kristina K. Gagalova, Readman Chiu, Chen Yang, René L. Warren, Inanc Birol
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Long-read sequencing technologies have improved significantly since their emergence. Their read lengths, potentially spanning entire transcripts, is advantageous for reconstructing transcriptomes. Existing long-read transcriptome assembly me
Externí odkaz:
https://doaj.org/article/e666fce257074849902656209c1fb357
Autor:
Johnathan Wong, Lauren Coombe, Vladimir Nikolić, Emily Zhang, Ka Ming Nip, Puneet Sidhu, René L. Warren, Inanç Birol
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Current state-of-the-art de novo long read genome assemblers follow the Overlap-Layout-Consensus paradigm. While read-to-read overlap – its most costly step – was improved in modern long read genome assemblers, these tools still often re
Externí odkaz:
https://doaj.org/article/d6a30448c4c845bb9eefc3dcce11fd5d
Autor:
Vladimir Nikolić, Amirhossein Afshinfard, Justin Chu, Johnathan Wong, Lauren Coombe, Ka Ming Nip, René L. Warren, Inanç Birol
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-15 (2022)
Abstract Background De novo genome assembly is essential to modern genomics studies. As it is not biased by a reference, it is also a useful method for studying genomes with high variation, such as cancer genomes. De novo short-read assemblers common
Externí odkaz:
https://doaj.org/article/1608ad11b7274ecfbe7adb1ab7c85711
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Emu (Dromaius novaehollandiae) farming has been gaining wide interest for fat production. Oil rendered from this large flightless bird’s fat is valued for its anti-inflammatory and antioxidant properties for uses in therapeutics and cosmet
Externí odkaz:
https://doaj.org/article/db4317381827499b9733fd43efabab32
Autor:
T. Roderick Docking, Jeremy D. K. Parker, Martin Jädersten, Gerben Duns, Linda Chang, Jihong Jiang, Jessica A. Pilsworth, Lucas A. Swanson, Simon K. Chan, Readman Chiu, Ka Ming Nip, Samantha Mar, Angela Mo, Xuan Wang, Sergio Martinez-Høyer, Ryan J. Stubbins, Karen L. Mungall, Andrew J. Mungall, Richard A. Moore, Steven J. M. Jones, İnanç Birol, Marco A. Marra, Donna Hogge, Aly Karsan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Several genomic features have been found for acute myeloid leukaemia (AML) but targeted clinical genetic testing fails to predict prognosis. Here, the authors generate an AML prognostic score from RNA-seq data of patients, which successfully stratifi
Externí odkaz:
https://doaj.org/article/b8f2ebaeb4ca47dbbfddf2abb90ffb18
Autor:
Simon Haile, Richard D. Corbett, Veronique G. LeBlanc, Lisa Wei, Stephen Pleasance, Steve Bilobram, Ka Ming Nip, Kirstin Brown, Eva Trinh, Jillian Smith, Diane L. Trinh, Miruna Bala, Eric Chuah, Robin J. N. Coope, Richard A. Moore, Andrew J. Mungall, Karen L. Mungall, Yongjun Zhao, Martin Hirst, Samuel Aparicio, Inanc Birol, Steven J. M. Jones, Marco A. Marra
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
RNA sequencing (RNAseq) has been widely used to generate bulk gene expression measurements collected from pools of cells. Only relatively recently have single-cell RNAseq (scRNAseq) methods provided opportunities for gene expression analyses at the s
Externí odkaz:
https://doaj.org/article/64eb43c6a0f04391b354df5ccac16ee4
Autor:
Diana Lin, Darcy Sutherland, Sambina Islam Aninta, Nathan Louie, Ka Ming Nip, Chenkai Li, Anat Yanai, Lauren Coombe, René L. Warren, Caren C. Helbing, Linda M. N. Hoang, Inanc Birol
Publikováno v:
Antibiotics, Vol 11, Iss 7, p 952 (2022)
Antibiotic resistance is a global health crisis increasing in prevalence every day. To combat this crisis, alternative antimicrobial therapeutics are urgently needed. Antimicrobial peptides (AMPs), a family of short defense proteins, are produced nat
Externí odkaz:
https://doaj.org/article/7845b064595447468c8c17b5d1390b6e
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Background RNA-seq is a powerful and cost-effective technology for molecular diagnostics of cancer and other diseases, and it can reach its full potential when coupled with validated clinical-grade informatics tools. Despite recent advances
Externí odkaz:
https://doaj.org/article/04c83c6e11664161bc6bc3eb730190a1
Autor:
Zhuyi Xue, René L. Warren, Ewan A. Gibb, Daniel MacMillan, Johnathan Wong, Readman Chiu, S. Austin Hammond, Chen Yang, Ka Ming Nip, Catherine A. Ennis, Abigail Hahn, Sheila Reynolds, Inanc Birol
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Alternative polyadenylation (APA) results in messenger RNA molecules with different 3′ untranslated regions (3’ UTRs), affecting the molecules’ stability, localization, and translation. APA is pervasive and implicated in can
Externí odkaz:
https://doaj.org/article/7b76dd89454a4e668ec2ad5f9b270701
Autor:
Johnathan Wong, Lauren Coombe, Vladimir Nikolić, Emily Zhang, Ka Ming Nip, Puneet Sidhu, René L Warren, Inanç Birol
MotivationCurrent state-of-the-art long readde novogenome assemblers follow the Overlap Layout Consensus (OLC) paradigm, an O(n2) algorithm in its naïve implementation. While the most time- and memory-intensive step of OLC —the all-vs-all sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5070269532091df78bdab64ccfb1d475
https://doi.org/10.1101/2022.10.25.513734
https://doi.org/10.1101/2022.10.25.513734
