Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ka Lung Andrew Chan"'
Autor:
Magnus Jensen, Shiyue Liu, Elzbieta Stepula, Davide Martella, Anahid A. Birjandi, Keith Farrell‐Dillon, Ka Lung Andrew Chan, Maddy Parsons, Ciro Chiappini, Sarah J. Chapple, Giovanni E. Mann, Tom Vercauteren, Vincenzo Abbate, Mads S. Bergholt
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Lipid metabolism and signaling play pivotal functions in biology and disease development. Despite this, currently available optical techniques are limited in their ability to directly visualize the lipidome in tissues. In this study, opto‐
Externí odkaz:
https://doaj.org/article/6c00e459bee24bc39260a84dd801ad2b
Publikováno v:
ACS Omega, Vol 5, Iss 22, Pp 12698-12706 (2020)
Externí odkaz:
https://doaj.org/article/258bbc586ea94bf2af19dcbd9b0854fa
Autor:
Hany M. Elsheikha, Alaa T. Al-Sandaqchi, Mohammad S. R. Harun, Francesca Winterton, Ali Altharawi, Nashwa A. Elsaied, Carl W. Stevenson, William MacNaughtan, John G. M. Mina, Paul W. Denny, Gianfelice Cinque, Ka Lung Andrew Chan
Publikováno v:
Cells, Vol 11, Iss 5, p 811 (2022)
Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the ho
Externí odkaz:
https://doaj.org/article/4f657002c9be4452a1f97321f5de9c4c
Autor:
Ameliya Dickson, Elise Cooper, Lenu B. Fakae, Bo Wang, Ka Lung Andrew Chan, Hany M. Elsheikha
Publikováno v:
Pathogens, Vol 9, Iss 9, p 763 (2020)
We examined the inhibitory effect of matcha green tea (Camellia sinensis) and epigallocatechin gallate (EGCg; the most abundant catechin in tea) on the vegetative growth and encystation of Acanthamoeba castellanii T4 genotype. The sulforhodamine B (S
Externí odkaz:
https://doaj.org/article/bf12feec6ae14c70bb21428ddba9a6ad
Autor:
Magnus Jensen, Shiyue Liu, Elzbieta Stepula, Davide Martella, Anahid A. Birjandi, Keith Farrell-Dillon, Ka Lung Andrew Chan, Maddy Parsons, Ciro Chiappini, Sarah J. Chapple, Giovanni E. Mann, Tom Vercauteren, Vincenzo Abbate, Mads S. Bergholt
Lipid metabolism and signalling play pivotal functions in biology and disease development. Despite this, there is currently no optical technique available that can directly visualise the lipidome in tissues. In this study, we introduce opto-lipidomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db6cb7e9aa8e25b08717cb9d4e3c84d
https://doi.org/10.1101/2023.04.01.534702
https://doi.org/10.1101/2023.04.01.534702
Publikováno v:
Alsalhi, M S, Royall, P G & Chan, K L A 2022, ' Mechanistic study of the solubilization effect of basic amino acids on a poorly water-soluble drug ', RSC Advances, vol. 12, no. 30, pp. 19040-19053 . https://doi.org/10.1039/D2RA02870K
Amino acids have shown promising abilities to form complexes with poorly water-soluble drugs and improve their physicochemical properties for a better dissolution profile through molecular interactions. Salt formation via ionization between acidic dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785a95d61cca7547ef911a45b5122014
https://kclpure.kcl.ac.uk/ws/files/177372108/Mechanistic_study_of_the_ALSAHI_Publishedonline29June2022_GOLD_VoR_CC_BY.pdf
https://kclpure.kcl.ac.uk/ws/files/177372108/Mechanistic_study_of_the_ALSAHI_Publishedonline29June2022_GOLD_VoR_CC_BY.pdf
Publikováno v:
Poonprasartporn, A & Chan, K L A 2022, ' Label-free study of intracellular glycogen level in Metformin and Resveratrol-treated insulin-resistant HepG2 by live-cell FTIR spectroscopy ', Biosensors and Bioelectronics, vol. 212, 114416 . https://doi.org/10.1016/j.bios.2022.114416
Conventional in vitro study often involves the destruction of the cells followed by purification and dilution steps before applying enzymatic assay or metabolomic analysis. It is a costly and laborious process, and it cannot monitor changes as a func
Publikováno v:
Altharawi, A, Rahman, M & Chan, A 2020, ' Identifying the responses from the estrogen receptor expressed MCF7 cells treated in anticancer drugs of different modes of action using live-cell FTIR spectroscopy ', ACS Omega, vol. 5, no. 22, acsomega.9b04369, pp. 12698–12706 . https://doi.org/10.1021/acsomega.9b04369
ACS Omega, Vol 5, Iss 22, Pp 12698-12706 (2020)
ACS Omega
ACS Omega, Vol 5, Iss 22, Pp 12698-12706 (2020)
ACS Omega
Recently, we have shown that changes in Fourier transform infrared (FTIR) spectra of living MDA-MB-231 cells (a triple negative cell line) upon exposure to anticancer drugs reflect the changes in the cellular compositions which are correlated to the
Autor:
Hany M. Elsheikha, Alaa T. Al-Sandaqchi, Mohammad S. R. Harun, Francesca Winterton, Ali Altharawi, Nashwa A. Elsaied, Carl W. Stevenson, William MacNaughtan, John G. M. Mina, Paul W. Denny, Gianfelice Cinque, Ka Lung Andrew Chan
Publikováno v:
Cells, 2022, Vol.11(5), pp.811 [Peer Reviewed Journal]
Cells; Volume 11; Issue 5; Pages: 811
Cells; Volume 11; Issue 5; Pages: 811
Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the ho
Autor:
Kenny Kai Ken Ting, Sook Mei Khor, Ka Lung Andrew Chan, Jee Kwan Ng, Feng H. Tay, Patrick Steven Wray, Siti Syazana Mohd Saberi
Publikováno v:
Ng, J K, Tay, F H, Wray, P S, Mohd Saberi, S S, Ting, K K K, Khor, S M & Chan, K L A 2021, ' Inexpensive Portable Infrared Device to Detect and Quantify Alcohols in Hand Sanitizers for Public Health and Safety ', Analytical Chemistry, vol. 93, no. 45, pp. 15015–15023 . https://doi.org/10.1021/acs.analchem.1c02652
The onset of Covid-19 pandemic has resulted in the exponential growth of alcohol-based hand rub (ABHR)/hand sanitizer use. Reports have emerged of ABHR products containing methanol, a highly toxic compound to humans, exposing users to acute and chron