Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ka Lok Ho"'
Autor:
Shuai Zha, Ka-Lok Ho, Chen Xie, Wing Yan Wong, Ga Lai Law, Jean-Claude G. Bünzli, Chi-Fai Chan, William Chi-Shing Tai, Rongfeng Lan, Hongguang Li, Yuxia Luo, Ka-Leung Wong, Brandon Dow Chan, Jing-Xiang Zhang
Publikováno v:
Journal of Medicinal Chemistry. 60:8923-8932
A unique, dual-function, photoactivatable anticancer prodrug, RuEuL, has been tailored that features a ruthenium(II) complex linked to a cyclen–europium chelate via a π-conjugated bridge. Under irradiation at 488 nm, the dark-inactive prodrug unde
Autor:
Sidney Tam, Bonnie Mei-Wah Fong, Margaret B. Murphy, Kelvin Sze-Yin Leung, Michael H.W. Lam, Man Shan Yau, Ka Ki Yuen, Ka Lok Ho, John P. Giesy, Yi Wan
Publikováno v:
Archives of Environmental Contamination and Toxicology. 73:410-420
Bisphenol A (BPA) glucuronide and sulfate conjugates are major products of Phase II metabolism of BPA in humans. In the past, their determination in body fluids usually involves tedious enzymatic hydrolysis and multiresidual analysis. The recent avai
Autor:
Ka Ki Yuen, Michael H.W. Lam, Man Shan Yau, Bonnie Mei-Wah Fong, John P. Giesy, Ka Lok Ho, Kelvin Sze-Yin Leung, Sidney Tam, Margaret B. Murphy, Yi Wan
Publikováno v:
Environment International, Vol 98, Iss, Pp 46-53 (2017)
3,3′,5,5′-Tetrabromobisphenol-A (TBBPA) is an important brominated flame retardant in epoxy, vinyl esters and polycarbonate resins. Previous studies have already shown the occurrence of its Phase II metabolites, TBBPA-glucuronide and sulfate conj
106
Objective: Hormones are substances secreted and regulated by organs of the human endocrine system. Even though hormones are not at a high concentration secreted in body, nevertheless they play an important role in maintaining normal physiolo
Objective: Hormones are substances secreted and regulated by organs of the human endocrine system. Even though hormones are not at a high concentration secreted in body, nevertheless they play an important role in maintaining normal physiolo
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/73qkj7
Autor:
Bonnie Mei-Wah Fong, Man Shan Yau, John P. Giesy, Yi Wan, Kelvin Sze-Yin Leung, Ka Lok Ho, Michael H.W. Lam, Margaret B. Murphy, Sidney Tam
Publikováno v:
Chemosphere. 133:6-12
One possible source of urinary bromophenol (BP) glucuronide and sulfate conjugates in mammalian animal models and humans is polybromodiphenyl ethers (PBDEs), a group of additive flame-retardants found ubiquitously in the environment. In order to stud
Autor:
Ga Lai Law, René M. Botnar, Chi-Fai Chan, Sara Lacerda, Cyrille Richard, Grégory Ramniceanu, Ka-Leung Wong, Bich-Thuy Doan, Bethany I. Harriss, Alkystis Phinikaridou, Nicholas J. Long, Ka-Lok Ho, Hongguang Li, Rongfeng Lan, Wai Sum Lo
Publikováno v:
Li, H, Harriss, B I, Phinikaridou, A, Lacerda, S, Ramniceanu, G, Doan, B-T, Ho, K-L, Chan, C-F, Lo, W-S, Botnar, R M, Lan, R, Richard, C, Law, G-L, Long, N J & Wong, K-L 2017, ' Gadolinium and Platinum in Tandem : Real-time Multi-Modal Monitoring of Drug Delivery by MRI and Fluorescence Imaging ', Nanotheranostics, vol. 1, no. 2, pp. 186-195 . https://doi.org/10.7150/ntno.18619
Nanotheranostics
Nanotheranostics, 2017, 1 (2), pp.186-195. ⟨10.7150/ntno.18619⟩
Nanotheranostics
Nanotheranostics, 2017, 1 (2), pp.186-195. ⟨10.7150/ntno.18619⟩
International audience; A novel dual-imaging cisplatin-carrying molecular cargo capable of performing simultaneous optical and MR imaging is reported herein. This long-lasting MRI contrast agent (r1 relaxivity of 23.4 mM-1s-1 at 3T, 25 oC) is a photo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7fed7e403897968ad5e2b924ddb3cc
https://kclpure.kcl.ac.uk/en/publications/aabf5f66-7986-4c02-9174-3d33ce631603
https://kclpure.kcl.ac.uk/en/publications/aabf5f66-7986-4c02-9174-3d33ce631603
Publikováno v:
Scientific Reports
Hydroxylated- and methoxylated- polybrominated diphenyl ethers (OH-PBDEs and MeO-PBDEs) are more toxic than PBDEs and occur widely in the marine environment, and yet their origins remain controversial. In this study, four species of microalgae (Isoch
Autor:
Bonnie Mei-Wah Fong, Margaret B. Murphy, Kelvin Sze-Yin Leung, John P. Giesy, Yi Wan, Michael H.W. Lam, Ka Lok Ho, Sidney Tam
Publikováno v:
Analytical Chemistry. 84:9881-9888
Bromophenol glucuronide and sulfate conjugates have been reported to be products of mammalian metabolism of polybrominated diphenyl ethers (PBDEs), a group of additive flame-retardants found ubiquitously in the environment. In order to explore their
Autor:
Hong-Sheng Wang, Ming Hung Wong, Li-Chen Ge, Michael H.W. Lam, Jun Du, Chris K C Wong, Ka-Lok Ho, Zhuojia Chen, John P. Giesy
Publikováno v:
Environment International, Vol 47, Iss, Pp 66-72 (2012)
Hydroxylated (OH-) and methoxylated (MeO-) polybrominated diphenyl ethers (PBDE) are suspected endocrine disruptors. Little is known about the accumulation or sources of these chemicals in tissues of humans, particularly those residing in Hong Kong,
Autor:
Jun Du, Ming Hung Wong, Ka Lok Ho, Hong-Bin Huang, Zhuo Jia Chen, Qing Liu, Michael H.W. Lam, Yu Bon Man, Han Yan Liu, Hong-Sheng Wang
Publikováno v:
Environmental research. 148
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) are attracting more and more attention for the neurodevelopment toxicity effects. We evaluated the concentrations of 15 individual OH-PBDEs and 3 bromophenol (BRP) congeners in 30 mother-newborn