Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ka Kei Ho"'
Autor:
Eric W.-F. Lam, Chwan-Deng Hsiao, Matthew J. Fuchter, R. Charles Coombes, Stephen S. Myatt, Paolo Di Fruscia, Ka-Kei Ho, Chun-Yuan Chen, Barrie Peck
SIRT proteins play an important role in the survival and drug resistance of tumor cells, especially during chemotherapy. In this study, we investigated the potency, specificity, and cellular targets of three SIRT inhibitors, Sirtinol, Salermide, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e521b746f43becc46569268e7a7bb25
https://doi.org/10.1158/1535-7163.c.6531518
https://doi.org/10.1158/1535-7163.c.6531518
Autor:
Eric W.-F. Lam, Chwan-Deng Hsiao, Matthew J. Fuchter, R. Charles Coombes, Stephen S. Myatt, Paolo Di Fruscia, Ka-Kei Ho, Chun-Yuan Chen, Barrie Peck
Supplementary Figure 1 from SIRT Inhibitors Induce Cell Death and p53 Acetylation through Targeting Both SIRT1 and SIRT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784bc64c2a631b8603a756d274850b4e
https://doi.org/10.1158/1535-7163.22484663
https://doi.org/10.1158/1535-7163.22484663
Autor:
Eric W-F. Lam, Sadaf Ghaem-Maghami, Jan J. Brosens, Roberto E. Dina, Luca Fusi, Ka-Kei Ho, Mark Christian, Lara J. Monteiro, Jun Wang, Stephen S. Myatt
Supplementary Figure 1 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cdb10275ef905d4d22bb1d95809993
https://doi.org/10.1158/0008-5472.22382649.v1
https://doi.org/10.1158/0008-5472.22382649.v1
Autor:
Eric W-F. Lam, Sadaf Ghaem-Maghami, Jan J. Brosens, Roberto E. Dina, Luca Fusi, Ka-Kei Ho, Mark Christian, Lara J. Monteiro, Jun Wang, Stephen S. Myatt
Supplementary Figure 2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e31a1e5a73a854c1d3c6d9d2d862caa
https://doi.org/10.1158/0008-5472.22382646.v1
https://doi.org/10.1158/0008-5472.22382646.v1
Autor:
Eric W-F. Lam, Sadaf Ghaem-Maghami, Jan J. Brosens, Roberto E. Dina, Luca Fusi, Ka-Kei Ho, Mark Christian, Lara J. Monteiro, Jun Wang, Stephen S. Myatt
Endometrial cancer is the most common malignancy of the lower female reproductive tract. The tumor suppressor FOXO1 is downregulated in endometrial cancer compared with normal endometrium but the underlying mechanisms are not well understood. Using m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ee095e9c20268e9ac17174c9c2a92cb
https://doi.org/10.1158/0008-5472.c.6500271
https://doi.org/10.1158/0008-5472.c.6500271
Autor:
Eric W-F. Lam, Sadaf Ghaem-Maghami, Jan J. Brosens, Roberto E. Dina, Luca Fusi, Ka-Kei Ho, Mark Christian, Lara J. Monteiro, Jun Wang, Stephen S. Myatt
Supplementary Figure Legends 1-2 from Definition of microRNAs That Repress Expression of the Tumor Suppressor Gene FOXO1 in Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f8ff4733952bb0676ceb6fe094cd10
https://doi.org/10.1158/0008-5472.22382643
https://doi.org/10.1158/0008-5472.22382643
Autor:
Fabrizio Vianello, Federica Villanova, Veronica Tisato, Stefania Lymperi, Ka-Kei Ho, Ana R. Gomes, David Marin, Dominique Bonnet, Jane Apperley, Eric W.-F. Lam, Francesco Dazzi
Publikováno v:
Haematologica, Vol 95, Iss 7 (2010)
Background Residual chronic myeloid leukemia disease following imatinib treatment has been attributed to the presence of quiescent leukemic stem cells intrinsically resistant to imatinib. Mesenchymal stromal cells in the bone marrow may favor the per
Externí odkaz:
https://doaj.org/article/35ae18b3eceb4d728e11af699a44f10c
Autor:
Ka-Kei Ho1, Rosivatz, Evelyn2, Gunn, Richard M.3,4, Smith, Mark E. B.3, Stavropoulou, Alexandra V.1, Rosivatz, Erika2, Numbere, Macba G.3, Wong, John B.3, Lafitte, Valerie G. H.3, Behrendt, Jonathan M.3, Myatt, Stephen S.1, Hailes, Helen C.3, Woscholski, Rüdiger2,4, Lam, Eric W.-F.1,4 eric.lam@imperial.ac.uk
Publikováno v:
FEBS Journal. Aug2009, Vol. 276 Issue 15, p4037-4050. 14p. 1 Diagram, 7 Graphs.
Autor:
Janice W. H. Tsang, Aleksandra K. Zwolinska, Anne Feltes, San Yu Wong, Ui-Soon Khoo, Maja Petkovic, Ana R. Gomes, Yuen-Nei Cheung, Christina T. Karadedou, Jie Chen, Eric Lam, Ka-Kei Ho, Jan J. Brosens, Kelvin Y.K. Chan
Publikováno v:
Oncogene
Vascular endothelial growth factor (VEGF) has a central role in breast cancer development and progression, but the mechanisms that control its expression are poorly understood. Breast cancer tissue microarrays revealed an inverse correlation between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::335e693c6476e0b592ffc7472296807a
https://doi.org/10.1038/onc.2011.368
https://doi.org/10.1038/onc.2011.368
Autor:
Sadaf Ghaem-Maghami, Eric Lam, Luca Fusi, Roberto Dina, Mark Christian, Ka-Kei Ho, Stephen S. Myatt, Lara J. Monteiro, Jan J. Brosens, Jun Wang
Publikováno v:
Cancer Research. 70:367-377
Endometrial cancer is the most common malignancy of the lower female reproductive tract. The tumor suppressor FOXO1 is downregulated in endometrial cancer compared with normal endometrium but the underlying mechanisms are not well understood. Using m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aab9014e0880239a92ae81b6f0883f1
https://doi.org/10.1158/0008-5472.can-09-1891
https://doi.org/10.1158/0008-5472.can-09-1891