Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ka Hong Wong"'
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background The integration of photodynamic therapy with a chemical drug-delivery system has displayed great potential in enhancing anticancer therapy. However, the solubility and non-specific biodistribution of both chemotherapeutic agents a
Externí odkaz:
https://doaj.org/article/f50ea49e7f5845b196f44c56f6e6d6ed
Publikováno v:
Microbial Cell Factories, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Triterpenoids have shown a wide range of biological activities including antitumor and antiviral effects. Typically, triterpenes are synthesized through the mevalonate pathway and are extracted from natural plants and fungi. In th
Externí odkaz:
https://doaj.org/article/628383d0a58a44cf8fabd5c51e7f78f6
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 4, Pp 475-490 (2022)
Dihydroartemisinin (DHA), a first-line antimalarial drug, has demonstrated great anticancer effects in many types of tumors, including liver cancer, glioblastoma, and pancreatic cancer. Due to its abilities to induce programmed cell death (PCD; apopt
Externí odkaz:
https://doaj.org/article/0d57855d8d5841e19d72b72c885a3ecb
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 1, Pp 100773- (2023)
Nano drug delivery systems have made significant progress in delivering anticancer drugs camptothecin (CPT). However, many challenges for CPT delivery remain, including low drug loading efficiency, premature drug leakage, and poor cellular internaliz
Externí odkaz:
https://doaj.org/article/b80b3c02e2a441fc9b9f5ebf26c6981c
Autor:
Xiao Huang, Hai Lin, Feng Huang, Yuning Xie, Ka Hong Wong, Xiaoyu Chen, Dongyue Wu, Aiping Lu, Zhijun Yang
Publikováno v:
Dose-Response, Vol 17 (2019)
Acute myeloid leukemia (AML) is a hematological malignancy, which is commonly associated with high incidence and mortality among adult patients. The standard induction regimen for AML has been substantially unchanged over the past 40 years, for which
Externí odkaz:
https://doaj.org/article/97655ed980084838b7e9bd9638eb1ca1
Publikováno v:
Molecules, Vol 25, Iss 16, p 3620 (2020)
Cancer is a global health challenge. There are drawbacks to conventional chemotherapy such as poor bioavailability, development of drug resistance and severe side effects. Novel drug delivery system may be an alternative to optimize therapeutic effec
Externí odkaz:
https://doaj.org/article/25988c8ee38e456083bda4ed36d3140b
Publikováno v:
Biomaterials Science. 11:1589-1606
Strategies for functionalization of PAMAM-based biomacromolecule delivery systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b955a76339da1c95771e0b52852f800
https://doi.org/10.1039/d2bm01677j
https://doi.org/10.1039/d2bm01677j
Publikováno v:
Acta Biomaterialia. 140:492-505
Ferroptosis is a novel cell death form against drug-resistance through bypassing apoptosis, but its therapeutic efficacy triggered by traditional iron-based nanomaterials or classic drug inducers has been far from satisfactory due to the high glutath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282129b6e966203d6fee218c68397ab0
https://doi.org/10.1016/j.actbio.2021.11.042
https://doi.org/10.1016/j.actbio.2021.11.042
Publikováno v:
Biomaterials Science. 10:1018-1025
The efficacy of photodynamic therapy (PDT) for cancer is limited owing to the abnormality of the tumor microenvironment (TME), such as the dysfunctional tumor vascular system leading to restricted drug distribution in tumor lesions, and hypoxia resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d2e2c97080f8f2f910191dc131e5ae
https://doi.org/10.1039/d1bm01802g
https://doi.org/10.1039/d1bm01802g
Publikováno v:
Acta biomaterialia. 145
Artesunate (AS), the first-line treatment of malaria with a satisfactory safety profile, has been repurposed as a potential anticancer candidate as it mainly generates reactive oxygen species (ROS) through its intrinsic endoperoxide bridge reacting w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c79749b346449fc00a3990ea7bfa9e1
https://pubmed.ncbi.nlm.nih.gov/35381398
https://pubmed.ncbi.nlm.nih.gov/35381398