Renal biopsies from donors with acute kidney injury show different molecular patterns according to the post-transplant function

Autor: Flavia Neri, Maria Letizia Lo Faro, Maria Kaisar, Ka Ho Tam, Martyna Borak, Jan Lindeman, Annalisa Angelini, Marny Fedrigo, Jesper Kers, James Hunter, Rutger Ploeg

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract The utilization of kidneys from donors with acute kidney injury (AKI) is often limited by unpredictable post-transplantation outcomes. The aim of our study was to identify protein mediators implicated in either recovery or failure of these o

Externí odkaz: https://doaj.org/article/a4815eee77584637b463c650c51d0755

Predicting clinical endpoints and visual changes with qualityweighted tissue-based renal histological features.

Autor: Ka Ho Tam, Maria F. Soares, Jesper Kers, Edward J. Sharples, Rutger J. Ploeg, Maria Kaisar, Jens Rittscher

Publikováno v: Frontiers in Transplantation; 2024, p1-17, 17p

Data from Brain-Derived Neurotrophic Factor Promotes Tumorigenesis via Induction of Neovascularization: Implication in Hepatocellular Carcinoma

Autor: Ronnie T.P. Poon, Sheung-Tat Fan, Ka-Ho Tam, Chi-Keung Lau, Zhen-Fan Yang, Chi-Tat Lam

Purpose: Brain-derived neurotrophic factor (BDNF) has emerged as a novel angiogenic factor, and yet its impact on tumorigenesis is unclear. This study aimed at investigating the roles of BDNF in angiogenesis and tumor development.Experimental Design:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446a498f53479e7f6908be596cf550c6
https://doi.org/10.1158/1078-0432.c.6518458

Self-Supervised Voxel-Level Representation Rediscovers Subcellular Structures in Volume Electron Microscopy

Autor: Hongqing Han, Mariia Dmitrieva, Alexander Sauer, Ka Ho Tam, Jens Rittscher

Publikováno v: 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39c19113c86d2c44d362df82bd9ad72d
https://doi.org/10.1109/cvprw56347.2022.00204

Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer

Autor: Danny Allen, Stephen J. Lockett, Ruth J. Muschel, Tamar Yechezkel, Paul Kinchesh, Boris Vojnovic, Alastair D. Lamb, Hanna T. Sjoberg, Dina Preise, Richard J. Bryant, Jens Rittscher, Ka Ho Tam, Adrian L. Harris, Ian G. Mills, Yiannis Philippou, Anette L Magnussen, Iain D. C. Tullis, Emma A Murphy, Lilach Agemy, Freddie C. Hamdy, David A. Wink, Andrea Chatrian, Avigdor Scherz, Sean Smart, Joël Lefebvre, Stuart Gilchrist, Esther Bridges, David A. Scheiblin

Publikováno v: Sjoberg, H T, Philippou, Y, Magnussen, A L, Tullis, I D C, Bridges, E, Chatrian, A, Lefebvre, J, Tam, K H, Murphy, E A, Rittscher, J, Preise, D, Agemy, L, Yechezkel, T, Smart, S C, Kinchesh, P, Gilchrist, S, Allen, D P, Scheiblin, D A, Lockett, S J, Wink, D A, Lamb, A D, Mills, I G, Harris, A, Muschel, R J, Vojnovic, B, Scherz, A, Hamdy, F C & Bryant, R J 2021, ' Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer ', British Journal of Cancer, vol. 125, pp. 534-546 . https://doi.org/10.1038/s41416-021-01450-6
British Journal of Cancer

Background There is a need to improve the treatment of prostate cancer (PCa) and reduce treatment side effects. Vascular-targeted photodynamic therapy (VTP) is a focal therapy for low-risk low-volume localised PCa, which rapidly disrupts targeted tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e332f7007516e12e8126b136968964
https://pure.qub.ac.uk/en/publications/tumour-irradiation-combined-with-vasculartargeted-photodynamic-therapy-enhances-antitumour-effects-in-preclinical-prostate-cancer(a26d16da-6c3f-41e3-84f7-b20bf56280b2).html