Zobrazeno 1 - 10
of 882
pro vyhledávání: '"Ka‐On Lam"'
Autor:
Lanqi Gong, Yu Zhang, Yuma Yang, Qian Yan, Jifeng Ren, Jie Luo, Yuen Chak Tiu, Xiaona Fang, Beilei Liu, Raymond Hiu Wai Lam, Ka‐On Lam, Anne Wing‐Mui Lee, Xin‐Yuan Guan
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3194-3211 (2022)
Abstract The tumor microenvironment (TME) is considered to be one of the vital mediators of tumor progression. Extracellular matrix (ECM), infiltrating immune cells, and stromal cells collectively constitute the complex ecosystem with varied biochemi
Externí odkaz:
https://doaj.org/article/2417c7107cde4ecc955f2f98a29b0b82
Autor:
Fei-Fei Zhang, Chen Jiang, Dong-Ping Jiang, Yu-Zhu Cui, Xin-Yue Wang, Liang-Zhan Sun, Miao Chen, Ka-On Lam, Sha-Yi Wu, Krista Verhoeft, Dora Lai-Wan Kwong, Xin-Yuan Guan
Publikováno v:
PLoS Genetics, Vol 19, Iss 2, p e1010640 (2023)
The molecular mechanism of tumor metastasis, especially how metastatic tumor cells colonize in a distant site, remains poorly understood. Here we reported that ARHGAP15, a Rho GTPase activating protein, enhanced gastric cancer (GC) metastatic coloniz
Externí odkaz:
https://doaj.org/article/47d8029dfdab46198d55046f560900ee
Autor:
Kin-Sang Lau, Ben Man-Fei Cheung, Ka-On Lam, Sum-Yin Chan, Ka-Ming Lam, Chun-Fai Yeung, Ivan Fan-Ngai Hung, Dora Lai-Wan Kwong, Chi-Chung Tong, To-Wai Leung, Mai-Yee Luk, Anne Wing-Mui Lee, Kwok-Keung Yuen, Victor Ho-Fun Lee
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Tuberculosis (TB) reactivation has been increasingly identified following immune checkpoint inhibitor (ICI) therapy for cancer patients. However there has been no report on TB reactivation in the gastrointestinal tract. In the rep
Externí odkaz:
https://doaj.org/article/2540bea4e0744c0db3e2bb0711216fb7
Autor:
Larry Ka-Yue Chow, Dittman Lai-Shun Chung, Lihua Tao, Kui Fat Chan, Stewart Yuk Tung, Roger Kai Cheong Ngan, Wai Tong Ng, Anne Wing-Mui Lee, Chun Chung Yau, Dora Lai-Wan Kwong, Victor Ho-Fun Lee, Ka-On Lam, Jiayan Liu, Honglin Chen, Wei Dai, Maria Li Lung
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104357- (2022)
Summary: Background: Epstein-Barr virus (EBV) latent infection is associated with genome-wide epigenomic changes in several malignancies, but its role in epigenetic dysregulation remains unclear in nasopharyngeal carcinoma (NPC). Methods: To investig
Externí odkaz:
https://doaj.org/article/2bc6dad55c7b4c878e2ab635d488677a
Autor:
Hao Yu, Ka-On Lam, Michael D. Green, Huanmei Wu, Li Yang, Weili Wang, Jianyue Jin, Chen Hu, Yang Wang, Shruti Jolly, Feng-Ming (Spring) Kong
Publikováno v:
Journal of the National Cancer Center, Vol 1, Iss 2, Pp 31-38 (2021)
Purpose: This study aimed to examine the effect of radiation esophagitis (RE) and the dynamics of RE on subsequent survival in non-small cell lung cancer (NSCLC) patients who underwent radiotherapy. Experimental Design: Patients with NSCLC treated wi
Externí odkaz:
https://doaj.org/article/9319e04b9edc47d0968fd45d7f5dcdbb
Autor:
Hao Yu, Fang Chen, Ka-On Lam, Li Yang, Yang Wang, Jian-Yue Jin, Aya EI Helali, Feng-Ming (Spring) Kong
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Radiation-induced lymphopenia is known for its survival significance in patients with breast cancer treated with radiation therapy. This study aimed to evaluate the impact of radiotherapy on lymphocytes by applying machine learning strategies. We use
Externí odkaz:
https://doaj.org/article/7b3f2d4c7510480fa073d7c3e12bf2bd
Autor:
Lanqi Gong, Dora Lai-Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Baifeng Zhang, Xiaona Fang, Li Liu, Min Luo, Beilei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Ho-Fun Lee, Ka-On Lam, Anthony Wing-Ip Lo, Zhiwei Chen, Yan Wang, Anne Wing-Mui Lee, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The tumor microenvironment can influence patient survival response to therapy. Here, the authors used single-cell sequencing to investigate the microenvironment of nasopharyngeal cancer and identify tumor-specific signatures in five stromal clusters
Externí odkaz:
https://doaj.org/article/0b2c6fcf4f674aa2b645939100155c52
Autor:
Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Here the authors report a major histocompatibility complex (MHC) association analysis for nasopharyngeal carcinoma in Chinese individuals from Hong Kong, finding 8 independent associated loci associated with lower risk for developing nasopharyngeal c
Externí odkaz:
https://doaj.org/article/f82cb968f4d947bb91dd4a6ed21c1e75
Autor:
Xiaobin Zhang, Ben M. Eyck, Yang Yang, Jun Liu, Yin-Kai Chao, Ming-Mo Hou, Tsung-Min Hung, Qingsong Pang, Zhen-Tao Yu, Hongjing Jiang, Simon Law, Ian Wong, Ka-On Lam, Berend J. van der Wilk, Ate van der Gaast, Manon C. W. Spaander, Roelf Valkema, Sjoerd M. Lagarde, Bas P. L. Wijnhoven, J. Jan B. van Lanschot, Zhigang Li
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background After neoadjuvant chemoradiotherapy (nCRT) for esophageal cancer, high pathologically complete response (pCR) rates are being achieved especially in patients with squamous cell carcinoma (SCC). An active surveillance strategy has
Externí odkaz:
https://doaj.org/article/2843509b1b4946d9b515bcdbaadad6c4
Autor:
Sik-Kwan Chan BSc, Sze-Chun Chau BSc, Sum-Yin Chan FRCR, Chi-Chung Tong FRCR, Ka-On Lam FRCR, Dora Lai-Wan Kwong MD, To-Wai Leung MD, Mai-Yee Luk FRCR, Anne Wing-Mui Lee MD, Horace Cheuk-Wai Choi PhD, Victor Ho-Fun Lee MD
Publikováno v:
Cancer Control, Vol 28 (2021)
Background Nasopharyngeal carcinoma (NPC) is endemic in Hong Kong with a skewed geographical and ethnic distribution. We performed an epidemiological study of NPC in Cheung Chau Island, a fishing village with very minimal residential mobility, and co
Externí odkaz:
https://doaj.org/article/a73dbb25e36e46d2bc886a774cf77a25