Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Ka, Bauer"'
Publikováno v:
Blood. 84:2214-2220
We analyzed the mutations in patients from 10 Polish kindreds with a bleeding diathesis due to factor VII deficiency. Patients from eight families had plasma levels of factor VII coagulant activity (VII:C) and factor VII antigen (VII:Ag) that were le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b3b76ba723f88bb16c2fdb0e5e6b218
https://doi.org/10.1182/blood.v84.7.2214.bloodjournal8472214
https://doi.org/10.1182/blood.v84.7.2214.bloodjournal8472214
Publikováno v:
Blood. 84:1314-1319
Virally inactivated, high-purity factor XI concentrates are available for treatment of patients with factor XI deficiency. However, preliminary experience indicates that some preparations may be thrombogenic. We evaluated whether a highly purified co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a66463f53d7407e4b20d50368de6e0e
https://doi.org/10.1182/blood.v84.4.1314.bloodjournal8441314
https://doi.org/10.1182/blood.v84.4.1314.bloodjournal8441314
Publikováno v:
Blood. 78:1744-1752
Fibrinogen Ledyard was discovered in a 10-year-old boy with a mild bleeding history. His father had the same defect and a bleeding history after surgery. Both patients were heterozygous. The plasma fibrinogen concentration was normal immunologically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b91a0c70f66f14698801a7fbccc77089
https://doi.org/10.1182/blood.v78.7.1744.bloodjournal7871744
https://doi.org/10.1182/blood.v78.7.1744.bloodjournal7871744
Publikováno v:
Blood. 76:2540-2545
Prothrombin complex concentrates (PCC), licensed for the treatment of hemophilia B, are known to carry a significant risk of thromboembolic complications. Although the reasons for thrombogenicity are not completely understood, several manufacturers h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6edd30f9179e6333e41841377f265bd
https://doi.org/10.1182/blood.v76.12.2540.bloodjournal76122540
https://doi.org/10.1182/blood.v76.12.2540.bloodjournal76122540
Publikováno v:
Blood. 76:2284-2289
Several investigators have reported that tumor necrosis factor (TNF) can alter the production of plasminogen activator type-1 (PAI-1) and plasminogen activators (PAs) by endothelial cells in vitro. We have examined the in vivo effects of recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218b4803bfd2c178ac6fb148c1b46b26
https://doi.org/10.1182/blood.v76.11.2284.bloodjournal76112284
https://doi.org/10.1182/blood.v76.11.2284.bloodjournal76112284
Publikováno v:
Europe PubMed Central
We investigated the mechanisms responsible for severe factor VII (FVII) deficiency in homozygous Italian patients with either Gly97Cys or Gln100Arg mutations in the second epidermal growth factor domain of FVII. Transient expression of complementary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::878252c4094e228449594fb820318666
https://pubmed.ncbi.nlm.nih.gov/10627125
https://pubmed.ncbi.nlm.nih.gov/10627125
Autor:
mathilde hunault, Marsh-Scott C, Jou C, Marshall R, Scheffel C, Ld, Fiore, Ka, Bauer, Mj, Mitchell
Publikováno v:
Europe PubMed Central
The factor V Leiden mutation, a G--A transition at position 1691 in exon 10 of the gene that codes for factor V, produces an Arg506Gln substitution and is the most common genetic risk factor for venous thrombosis. We have developed a rapid, sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b402767bd9c6fb185ec6275c450bb3a4
https://pubmed.ncbi.nlm.nih.gov/9895336
https://pubmed.ncbi.nlm.nih.gov/9895336
Autor:
Da, Lane, Pm, Mannucci, Ka, Bauer, Rm, Bertina, Np, Bochkov, Boulyjenkov V, Chandy M, Bjorn Dahlback, Ek, Ginter, Jp, Miletich, Fr, Rosendaal, Seligsohn U
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::138fbd084cd70209e723cc89f9d88846
https://pubmed.ncbi.nlm.nih.gov/8971998
https://pubmed.ncbi.nlm.nih.gov/8971998
Publikováno v:
Blood. 76(4)
Despite significant progress in elucidating the biochemistry of the hemostatic mechanism, the process of blood coagulation in vivo remains poorly understood. Factor IX is a vitamin K-dependent glycoprotein that can be activated by factor XIa or the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e624507cd736296e787e4e5846a6f3
https://pubmed.ncbi.nlm.nih.gov/2383653
https://pubmed.ncbi.nlm.nih.gov/2383653
Publikováno v:
Blood. 74:165-172
Several investigators have reported that tumor necrosis factor (TNF) can alter the hemostatic properties of vascular endothelial cells in vitro. We have examined the in vivo effects on the hemostatic mechanism of recombinant human TNF administered as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65b8a858fd19ed04a177aa455941f3a
https://doi.org/10.1182/blood.v74.1.165.bloodjournal741165
https://doi.org/10.1182/blood.v74.1.165.bloodjournal741165