Zobrazeno 1 - 10
of 282
pro vyhledávání: '"KYUNG-SOOK CHUNG"'
Autor:
So-Won Heo, Kyung-Sook Chung, Huy-Seoung Heo, Ye-Rin Kim, Chang-Seon Na, Hye-Shin Ahn, Yu-Kyong Shin, Kyung-Tae Lee
Publikováno v:
Journal of Functional Foods, Vol 119, Iss , Pp 106323- (2024)
Obesity causes various complications like type 2 diabetes and fatty liver, and as the proportion of obese patients increases worldwide, the discovery of new treatments has become necessary. Here, we evaluated the in vitro and in vivo anti-obesity eff
Externí odkaz:
https://doaj.org/article/a4ef2edb8033471183a84fe78384ebb7
Autor:
Seon Ju Mun, Yeon-Hwa Hong, Yongbo Shin, Jaeseo Lee, Hyun-Soo Cho, Dae-Soo Kim, Kyung-Sook Chung, Myung Jin Son
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Genetic liver disease modeling is difficult because it is challenging to access patient tissue samples and to develop practical and relevant model systems. Previously, we developed novel proliferative and functional liver organoids from plur
Externí odkaz:
https://doaj.org/article/642e2912486f4595a8dd329a309d912c
Publikováno v:
Journal of Chemistry, Vol 2024 (2024)
Endogenous prostaglandin E2 (PGE2) plays an important role in maintaining the homeostasis conditions. However, the overexpression of PGE2 in response to various inflammatory stimulations is an important target of anti-inflammatory drugs. Both inducib
Externí odkaz:
https://doaj.org/article/4a377208c193482d8c6e8d10b7595e6f
Autor:
Ahmed H. E. Hassan, Yeon Il Oh, Chae Hyeon Lee, Yeon Ju Kim, Soo Bin Cho, Md. Maqusood Alam, Sang-Eun Park, Kyung-Sook Chung, Kyung-Tae Lee, Yong Sup Lee
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Phenethyl-based edelfosine-analogs with saturated, monounsaturated, or polyunsaturated alkoxy substituents on phenyl ring were designed as novel antitumor lipids modulating p38 MAPK. Evaluation of the synthesised compounds against nine panels of dive
Externí odkaz:
https://doaj.org/article/c593553338f64ac58bc7690f590ec50e
Autor:
Seo-Jung Han, Jae Eun Jung, Do Hee Oh, Minsup Kim, Jae-Min Kim, Kyung-Sook Chung, Hee-Soo Han, Jeong-Hun Lee, Kyung-Tae Lee, Hee Jin Jeong, In Ho Park, Eunkyeong Jeon, Jeon-Soo Shin, Dongkeun Hwang, Art E. Cho, Duck-Hyung Lee, Taebo Sim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1257-1277 (2022)
Identification of highly selective type II kinase inhibitors is described. Two different chiral peptidomimetic scaffolds were introduced on the tail region of non-selective type II kinase inhibitor GNF-7 to enhance the selectivity. Kinome-wide select
Externí odkaz:
https://doaj.org/article/c5691771b8354940857012412b9bca79
Autor:
Hyo-Suk Ahn, Jae-Sung Ryu, Jaeseo Lee, Seon Ju Mun, Yeon-Hwa Hong, Yongbo Shin, Kyung-Sook Chung, Myung Jin Son
Publikováno v:
Cell Journal, Vol 24, Iss 3, Pp 133-139 (2022)
Objective: Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare type of primary liver cancer with characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC). The pathogenesis of cHCCCC is poorly understood due to a
Externí odkaz:
https://doaj.org/article/00d53389845544ad870ed67297f606df
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102950- (2022)
Given the advantage of being able to be extracted by a minimally invasive method, blood is regarded as a suitable cell source for reprogramming to establish induced pluripotent stem cells (iPSCs). Therefore, iPSCs established from patient derived per
Externí odkaz:
https://doaj.org/article/63aa25aca5044de6a4b9f44e82e3535a
Autor:
Bo-Ram Jin, Kyung-Sook Chung, Soonjae Hwang, Sam Noh Hwang, Ki-Jong Rhee, Minho Lee, Hyo-Jin An
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 6, Pp 561-573 (2021)
Previously, we found that rosmarinic acid (RA) exerted anti-inflammatory activities in a dextran sulfate sodium (DSS)-induced colitis model. Here, we investigated the anti-tumor effects of RA on colitis-associated colon cancer (CAC) and the underlyin
Externí odkaz:
https://doaj.org/article/9e3ddf76ec6e4c8289ee6b9fe6e30f62
Autor:
Seo-Yeon Kim, Ahmed H.E. Hassan, Kyung-Sook Chung, Su-Yeon Kim, Hee-Soo Han, Hwi-Ho Lee, Seang-Hwan Jung, Kwang-Young Lee, Ji-Sun Shin, Eungyeong Jang, Seolmin Yoon, Yong Sup Lee, Kyung-Tae Lee
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Graphical Abstract
Externí odkaz:
https://doaj.org/article/90d6deb984344626b776bea046df0d7b
Autor:
Hee-Soo Han, Seo-Yeon Kim, Ji-Sun Shin, Hwi-Ho Lee, Kyung-Sook Chung, Young Kyoung Rhee, Chang-Won Cho, Hee-Do Hong, Kyung-Tae Lee
Publikováno v:
Journal of Functional Foods, Vol 87, Iss , Pp 104765- (2021)
Sepsis is a life-threatening condition that can result in death accompanied by multiple organ failure. Here, we investigated the preventive effects of BLE0, a polysaccharide fraction isolated from young barley leaves (Hordeum vulgare L.), on colonic
Externí odkaz:
https://doaj.org/article/1b43748638cd4b34af367b57696d58d8