Zobrazeno 1 - 10
of 110
pro vyhledávání: '"KYUNG-SOO INN"'
Autor:
Namkwon Kim, In Gyoung Ju, Seung Ho Jeon, Yeongae Lee, Min-Ji Jung, Min Sung Gee, Jae Seok Cho, Kyung-Soo Inn, Lee Ann Garrett-Sinha, Myung Sook Oh, Jong Kil Lee
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background The gut microbiota has recently attracted attention as a pathogenic factor in Alzheimer’s disease (AD). Microfold (M) cells, which play a crucial role in the gut immune response against external antigens, are also exploited for
Externí odkaz:
https://doaj.org/article/05472f880fb74e1aaeea256535d8861f
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
T cells regulate adaptive immune responses through complex signaling pathways mediated by T cell receptor (TCR). The functional domains of the TCR are combined with specific antibodies for the development of chimeric antigen receptor (CAR) T cell the
Externí odkaz:
https://doaj.org/article/9fa4d6ba8b6f4010834b463ce47f970a
Autor:
Min Sung Gee, Seung Hwan Son, Seung Ho Jeon, Jimin Do, Namkwon Kim, Yeon-Joo Ju, Soo Jin Lee, Eun Kyoung Chung, Kyung-Soo Inn, Nam-Jung Kim, Jong Kil Lee
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2020)
Abstract Background Chronic neuroinflammation, aggressive amyloid beta (Aβ) deposition, neuronal cell loss, and cognitive impairment are pathological presentations of Alzheimer’s disease (AD). Therefore, resolution of neuroinflammation and inhibit
Externí odkaz:
https://doaj.org/article/b1ea94564d774370a4ff5064f7f2dfe3
Autor:
Dong-Hun Lee, Ki-Back Chu, Hae-Ji Kang, Su-Hwa Lee, Manika Chopra, Hyo-Jick Choi, Eun-Kyung Moon, Kyung-Soo Inn, Fu-Shi Quan
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Despite the extensive endeavours, developing an effective malaria vaccine remains as a great challenge. Apical membrane antigen 1 (AMA-1) located on the merozoite surface of parasites belonging to the genus Plasmodium is involved
Externí odkaz:
https://doaj.org/article/436acf49e9ca4d07bee47461ac02fb4e
Autor:
Yeon-Sook Kim, Abdimadiyeva Aigerim, Uni Park, Yuri Kim, Ji-Young Rhee, Jae-Phil Choi, Wan Beom Park, Sang Won Park, Yeonjae Kim, Dong-Gyun Lim, Kyung-Soo Inn, Eung-Soo Hwang, Myung-Sik Choi, Nam-Hyuk Cho
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 6, Pp 1161-1168 (2019)
The unexpectedly large outbreak of Middle East respiratory syndrome in South Korea in 2015 was initiated by an infected traveler and amplified by several “superspreading” events. Previously, we reported the emergence and spread of mutant Middle E
Externí odkaz:
https://doaj.org/article/39154946e5b34e02a1c2c7d5e61d1c67
Autor:
Namkwon Kim, Jimin Do, Jae-sung Bae, Hee Kyung Jin, Jong-Ho Kim, Kyung-Soo Inn, Myung Sook Oh, Jong Kil Lee
Publikováno v:
Journal of Pharmacological Sciences, Vol 137, Iss 2, Pp 195-201 (2018)
Inflammatory processes in the central nervous system are feature among biological reactions to harmful stimuli such as pathogens and damaged cells. In resting conditions, microglia are involved in immune surveillance and brain homeostasis. However, t
Externí odkaz:
https://doaj.org/article/9c697287c7294d399d1cad0ffabb82b7
Autor:
Ga Yeong Kim, Chae Won Song, Yo-Sep Yang, Na-Rae Lee, Hyung-Seok Yoo, Seung Hwan Son, Soo Jin Lee, Jong Seon Park, Jong Kil Lee, Kyung-Soo Inn, Nam-Jung Kim
Publikováno v:
Molecules, Vol 26, Iss 9, p 2525 (2021)
A series of PROTACs (PROteolysis-TArgeting Chimeras) consisting of bicalutamide analogs and thalidomides were designed, synthesized, and biologically evaluated as novel androgen receptor (AR) degraders. In particular, we found that PROTAC compound 13
Externí odkaz:
https://doaj.org/article/32dd86b792cc47b8baed18485d0d87de
Autor:
Chan-Ki Min, Hong-II Kim, Na-Young Ha, Yuri Kim, Eun-Kyung Kwon, Nguyen Thi Hai Yen, Je-In Youn, Yoon Kyung Jeon, Kyung-Soo Inn, Myung-Sik Choi, Nam-Hyuk Cho
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Despite the various roles of type I interferon (type I IFN) responses during bacterial infection, its specific effects in vivo have been poorly characterized in scrub typhus caused by Orientia tsutsugamushi infection. Here, we show that type I IFNs a
Externí odkaz:
https://doaj.org/article/337a2bfbc908468097d0235611c974a8
Autor:
Na-Rae Lee, Junsu Ban, Noh-Jin Lee, Chae-Min Yi, Ji-Yoon Choi, Hyunbin Kim, Jong Kil Lee, Jihye Seong, Nam-Hyuk Cho, Jae U. Jung, Kyung-Soo Inn
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Autophagy has been implicated in innate immune responses against various intracellular pathogens. Recent studies have reported that autophagy can be triggered by pathogen recognizing sensors, including Toll-like receptors and cyclic guanosine monopho
Externí odkaz:
https://doaj.org/article/1bfa347b8c064074aca0e1b2f7f0ecd5
Publikováno v:
Viruses, Vol 10, Iss 12, p 716 (2018)
Respiratory syncytial virus (RSV) causes severe acute lower respiratory tract disease. Retinoic acid-inducible gene-I (RIG-I) serves as an innate immune sensor and triggers antiviral responses upon recognizing viral infections including RSV. Since tr
Externí odkaz:
https://doaj.org/article/ae8e419c3a4d430a9c6f23d1d3fdda68