Zobrazeno 1 - 10
of 113
pro vyhledávání: '"KYUNG-CHEOL SOHN"'
Autor:
Kyeong Ah Park, Chan Seok Jung, Kyung-Cheol Sohn, Eunjin Ju, Sanghee Shin, InWha Park, MinKyun Na, Gang Min Hur
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28092- (2024)
Ubiquitination of RIPK1 plays an essential role in the recruitment of the IKK complex, an upstream component of pro-survival NF-κB. It also limits TNF-induced programmed cell death by inhibiting the spatial transition from TNFR1-associated complex-I
Externí odkaz:
https://doaj.org/article/cd093fc4e66a44d782ed0140992fd3e6
Autor:
Jeongkwan Hong, Kyung-Cheol Sohn, Hye-Won Park, Hyoeun Jeon, Eunjin Ju, Jae-Geun Lee, Jeong-Soo Lee, Jaerang Rho, Gang Min Hur, Hyunju Ro
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101202- (2024)
The transgene toggling device is recognized as a powerful tool for gene- and cell-based biological research and precision medicine. However, many of these devices often operate in binary mode, exhibit unacceptable leakiness, suffer from transgene sil
Externí odkaz:
https://doaj.org/article/1d190467eb3446cf855d38081be8cc2e
Autor:
Jeongkwan Hong, Jae-Geun Lee, Kyung-Cheol Sohn, Kayoung Lee, Seoee Lee, Jinyoung Lee, Jihye Hong, Dongju Choi, Yeseul Hong, Hyo Sun Jin, Dae-Kyoung Choi, Su Ui Lee, Yun Kee, Jangham Jung, Young-Ki Bae, Ran Hee Hwang, Gang Min Hur, Jeong-Soo Lee, Hyunju Ro
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Hong et al. describe a new transgene expression system, IQ-Switch, and its variants and characterize their applications in cell culture and zebrafish systems. They show that IQ-Switch system has several advantages over the previous inducible transgen
Externí odkaz:
https://doaj.org/article/679ef2ee8bca479ab46322ec7e98df3b
Autor:
Yu Ra Jung, Jin-Hyup Lee, Kyung-Cheol Sohn, Young Lee, Young-Joon Seo, Christos C Zouboulis, Chang-Deok Kim, Jeung-Hoon Lee, Seung-Phil Hong, Seong-Jun Seo, Seong-Jin Kim, Myung Im
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185081 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0169824.].
Externí odkaz:
https://doaj.org/article/c8d65b88bc4a49448aab6f6728130a7b
Autor:
Yu Ra Jung, Jin-Hyup Lee, Kyung-Cheol Sohn, Young Lee, Young-Joon Seo, Chang-Deok Kim, Jeung-Hoon Lee, Seung-Phil Hong, Seong-Jun Seo, Seong-Jin Kim, Myung Im
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169824 (2017)
Adiponectin plays important roles in metabolic function, inflammation and multiple biological activities in various tissues. However, evidence for adiponectin signaling in sebaceous glands is lacking, and its role remains to be clarified. This study
Externí odkaz:
https://doaj.org/article/a2484e6181a44a27a1e8f99f5ed73c1a
Autor:
Seoghyun Lee, Kyung-Cheol Sohn, Dae-Kyoung Choi, Minho Won, Kyeong Ah Park, Sung-Kyu Ju, Kidong Kang, Young-Ki Bae, Gang Min Hur, Hyunju Ro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Controlled gene expression is an indispensable technique in biomedical research. Here, we report a convenient, straightforward, and reliable way to induce expression of a gene of interest with negligible background expression compared to the most wid
Externí odkaz:
https://doaj.org/article/03508e2eb8f54afeb45f6d265bc01643
Autor:
Kyung-Cheol Sohn, Zheng Jun Li, Dae-Kyoung Choi, Tiejun Zhang, Jae Woo Lim, In-Kyu Chang, Gang Min Hur, Myung Im, Young Lee, Young-Joon Seo, Jeung-Hoon Lee, Chang Deok Kim
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95337 (2014)
Imiquimod, a nucleoside analogue of the imidazoquinoline family, is being used to treat various cutaneous cancers including squamous cell carcinoma (SCC). Imiquimod activates anti-tumor immunity via Toll-like receptor 7 (TLR7) in macrophage and other
Externí odkaz:
https://doaj.org/article/236aaa9f6fd84fad9c81f64abf9368e0
Autor:
Jung-Min Shin, Mi Yoon Kim, Kyung-Cheol Sohn, So-Young Jung, Hae-Eul Lee, Jae Woo Lim, Sooil Kim, Young-Ho Lee, Myung Im, Young-Joon Seo, Chang Deok Kim, Jeung-Hoon Lee, Young Lee, Tae-Jin Yoon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96035 (2014)
Nrf2 plays a role in protection of cells against oxidative stress and xenobiotic damage by regulating cytoprotective genes. In this study, we investigated the effect of Nrf2 on melanogenesis in normal human melanocytes (NHMCs). When NHMCs were transd
Externí odkaz:
https://doaj.org/article/b30d0e3238a9474f91418e8cabc990ee
Autor:
Ge Shi, Kyung-Cheol Sohn, Zhengjun Li, Dae-Kyoung Choi, Young Min Park, Jin-Hwa Kim, Yi-Ming Fan, Yong Hee Nam, Sooyeon Kim, Myung Im, Young Lee, Young-Joon Seo, Chang Deok Kim, Jeung-Hoon Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54355 (2013)
In this study, we investigated the expression and putative role of Sox9 in epidermal keratinocyte. Immunohistochemical staining showed that Sox9 is predominantly expressed in the basal layer of normal human skin epidermis, and highly expressed in sev
Externí odkaz:
https://doaj.org/article/e8b0514563b14bb4948d4fad7544f96f
Autor:
Zheng Jun Li, Kyung-Cheol Sohn, Dae-Kyoung Choi, Ge Shi, Dongkyun Hong, Han-Eul Lee, Kyu Uang Whang, Young Ho Lee, Myung Im, Young Lee, Young-Joon Seo, Chang Deok Kim, Jeung-Hoon Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77159 (2013)
Imiquimod is known to exert its effects through Toll-like receptor 7 (TLR7) and/or TLR8, resulting in expression of proinflammatory cytokines and chemokines. Keratinocytes have not been reported to constitutively express TLR7 and TLR8, and the action
Externí odkaz:
https://doaj.org/article/ef4cc8d94f644d399d50bf8ed9060a8c