Výsledky vyhledávání

366-OR: 14-3-3-ζ Contributes to Effect of ß-Cell GLP1 Receptor Signaling to Alter a-Cell Proglucagon Processing

Autor: MARLENA HOLTER, DARYL PHUONG, ISAAC S.H. LEE, MRIDUSMITA SAIKIA, LISA A. WEIKERT, ELIZABETH T. ANDERSON, QIN FU, SHENG ZHANG, KYLE SLOOP, BETHANY CUMMINGS

Publikováno v: Diabetes. 71

Glucagon like peptide 1 (GLP1) , a classically gut derived hormone, potentiates insulin secretion. New evidence suggests that α cells can produce GLP1 under certain conditions, which may offer a novel therapeutic modality for treating diabetes; howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b62e2ed4e11585e9669777469b43c320
https://doi.org/10.2337/db22-366-or

Zobrazit plný text záznamu

336-OR: A First-in-Human Single- and Multiple-Ascending Dose Study Evaluating Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Novel Oral Nonpeptide GLP-1 Receptor Agonist in Healthy Subjects

Autor: EDWARD J. PRATT, XIAOSU MA, RONG LIU, DEBORAH A. ROBINS, KYLE SLOOP, CHARLES BENSON

Publikováno v: Diabetes. 71

Background: LY3502970 (LY) is a novel, highly potent, orally bioavailable nonpeptide GLP-1 receptor agonist (RA) , and a potential alternative to injectable therapies or oral peptides whose absorption is affected by food or water intake. Objectives o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db7bad2342583fa0bdaabf910a50af6f
https://doi.org/10.2337/db22-336-or

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání