ABCC1 modulates negative feedback control of the hypothalamic-pituitary-adrenal axis in vivo in humans

Autor: Kyle, Catriona J., Nixon, Mark, Homer, Natalie Z.M., Morgan, Ruth A., Andrew, Ruth, Stimson, Roland H., Walker, Brian R.

Publikováno v: In Metabolism March 2022 128

The ATP-binding cassette proteins ABCB1 and ABCC1 as modulators of glucocorticoid action

Autor: Devine, Kerri, Villalobos, Elisa, Kyle, Catriona J., Andrew, Ruth, Reynolds, Rebecca M., Stimson, Roland H., Nixon, Mark, Walker, Brian R.

Publikováno v: Nature Reviews Endocrinology; February 2023, Vol. 19 Issue: 2 p112-124, 13p

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides

Autor: Weir, Graeme, Ramage, Lynne E., Akyol, Murat, Rhodes, Jonathan K., Kyle, Catriona J., Fletcher, Alison M., Craven, Thomas H., Wakelin, Sonia J., Drake, Amanda J., Gregoriades, Maria-Lena, Ashton, Ceri, Weir, Nick, van Beek, Edwin J.R., Karpe, Fredrik, Walker, Brian R., Stimson, Roland H.

Publikováno v: In Cell Metabolism 5 June 2018 27(6):1348-1355

GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement

Autor: Melvin, Audrey, Chantzichristos, Dimitrios, Kyle, Catriona J, Mackenzie, Scott D, Walker, Brian R, Johannsson, Gudmundur, Stimson, Roland H, O'Rahilly, Stephen

CONTEXT: GDF15 is a stress-induced hormone acting in the hindbrain that activates neural circuitry involved in establishing aversive responses and reducing food intake and body weight in animal models. Anorexia, weight loss, nausea and vomiting are c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e89507ff3427408932017ac9b0e62be3

Proof of concept for a superior therapeutic index of corticosterone compared with hydrocortisone in patients with congenital adrenal hyperplasia.

Autor: Kyle CJ; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Boyle LD; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Nixon M; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Homer NZM; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Simpson JP; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Rutter A; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Ramage LE; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Kelman A; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Freel EM; Queen Elizabeth University Hospital, Glasgow, G51 4TF, United Kingdom., Andrew R; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom., Walker BR; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE4 5PL, United Kingdom., Stimson RH; University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ, United Kingdom.

Publikováno v: European journal of endocrinology [Eur J Endocrinol] 2024 Nov 27; Vol. 191 (6), pp. 535-544.