Mechanistic Insight into Apoptotic Induction in Human Rhabdomyosarcoma and Breast Adenocarcinoma Cells by Chnoospora minima: A Sri Lankan Brown Seaweed

Autor: P. Ranasinghe, KW Samarakoon, Thilina Lakmini Gunathilaka, L Dinithi C Peiris, Kulathungage Hiranthi Dilrangi

Publikováno v: Pharmaceuticals
Volume 14
Issue 11
Pharmaceuticals, Vol 14, Iss 1154, p 1154 (2021)

The current study determined the cytotoxic and apoptotic potential of the polyphenol-rich methanol extract of Chnoospora minima (C. minima) and its fractions against human breast adenocarcinoma (MCF-7) and rhabdomyosarcoma (RMS) cells. MTT and neutra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd9e4aa23d51791b3e58d923179a90f
https://doi.org/10.3390/ph14111154

Chnoospora minima: a Robust Candidate for Hyperglycemia Management, Unveiling Potent Inhibitory Compounds and Their Therapeutic Potential.

Autor: Gunathilaka TL; Department of Zoology, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka. thilina@dss.cmb.ac.lk.; Department of Basic Science and Social Science for Nursing, Faculty of Nursing, University of Colombo, Sri Jayewardenepura, Thalapathpitiya, Nugegoda, 10250, Sri Lanka. thilina@dss.cmb.ac.lk., Bandaranayake U; Genetics & Molecular Biology Unit (Center for Biotechnology), Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka., Boudjelal M; King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh, 11481, Saudi Arabia., Ali R; King Abdullah International Medical Research Center (KAIMRC), King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard-Health Affairs, Riyadh, 11481, Saudi Arabia., Silva RM; Department of Statistics, Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka., Samarakoon KW; Institute for Combinatorial Advanced Research and Education (KDU-CARE), General Sir John Kotelawala Defence University, Ratmalana, 10390, Sri Lanka., Ranasinghe P; Industrial Technology Institute, Halbarawa Gardens, Malabe, 10115, Sri Lanka., Peiris LDC; Genetics & Molecular Biology Unit (Center for Biotechnology), Faculty of Applied Sciences, University of Sri Jayewardenepura, Nugegoda, 10250, Sri Lanka. dinithi@sci.sjp.ac.lk.

Publikováno v: Marine biotechnology (New York, N.Y.) [Mar Biotechnol (NY)] 2024 Dec; Vol. 26 (6), pp. 1231-1245. Date of Electronic Publication: 2024 Sep 11.

Structural Characterization and Anti-Inflammatory Effects of 24-Methylcholesta-5(6), 22-Diene-3β-ol from the Cultured Marine Diatom Phaeodactylum tricornutum ; Attenuate Inflammatory Signaling Pathways.

Autor: Samarakoon KW; Institute for Combinatorial Advanced Research and Education (KDU-CARE), General Sir John Kotelawala Defence University, Ratmalana 10390, Sri Lanka.; Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea., Kuruppu AI; Institute for Combinatorial Advanced Research and Education (KDU-CARE), General Sir John Kotelawala Defence University, Ratmalana 10390, Sri Lanka., Ko JY; Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea.; Research Institute of Basic Sciences, Incheon National University, Incheon 406-772, Republic of Korea., Lee JH; Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea.; Lee Gill Ya Cancer and Diabetes Institute, Incheon 406-840, Republic of Korea., Jeon YJ; Department of Marine Life Sciences, Jeju National University, Jeju 690-756, Republic of Korea.

Publikováno v: Marine drugs [Mar Drugs] 2023 Apr 03; Vol. 21 (4). Date of Electronic Publication: 2023 Apr 03.

In-Vitro Antioxidant, Hypoglycemic Activity, and Identification of Bioactive Compounds in Phenol-Rich Extract from the Marine Red Algae Gracilaria edulis (Gmelin) Silva.

Autor: Gunathilaka TL; Department of Zoology, Faculty of Applied Sciences (Center for Instrumentation Facility & Center for Biotechnology), University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka. gunathilakathilina2@gmail.com., Samarakoon KW; National Science and Technology Commission, Dudley Senanayake Mawatha, Colombo 8 00800, Sri Lanka. kalpa.samarakoon@gmail.com., Ranasinghe P; Industrial Technology Institute, Halbarawa Gardens, Malabe 10115, Sri Lanka. pathmasiri@iti.lk., Peiris LDC; Department of Zoology, Faculty of Applied Sciences (Center for Instrumentation Facility & Center for Biotechnology), University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka. dinithi@sci.sjp.ac.lk.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2019 Oct 15; Vol. 24 (20). Date of Electronic Publication: 2019 Oct 15.

A fucoidan fraction purified from Chnoospora minima; a potential inhibitor of LPS-induced inflammatory responses.

Autor: Fernando IPS; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea., Sanjeewa KKA; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea., Samarakoon KW; Industrial Technology Institute (ITI), 363, Bauddhaloka Mawatha, Colombo 7, Sri Lanka., Lee WW; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea., Kim HS; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea., Kang N; Department of Marine Bio-food Science, College of Fisheries and Ocean Sciences, Chonnam National University, 500-749, Republic of Korea., Ranasinghe P; Industrial Technology Institute (ITI), 363, Bauddhaloka Mawatha, Colombo 7, Sri Lanka., Lee HS; Marine Natural Products Laboratory, Korea Ocean Research and Development Institute, P.O. box 29, Ansan 426-744, Republic of Korea. Electronic address: hslee@kiost.ac., Jeon YJ; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea. Electronic address: youjin2014@gmail.com.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2017 Nov; Vol. 104 (Pt A), pp. 1185-1193. Date of Electronic Publication: 2017 Jul 06.