Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics leading to infant mortality

Autor: Sabharwal, Ankit, Gupta, Vishu, KV, Shamsudheen, Kumar Manokaran, Ranjith, Verma, Ankit, Mishra, Anushree, Bhoyar, Rahul C., Jain, Abhinav, Sivadas, Ambily, Rawat, Sonali, Jolly, Bani, Mohanty, Sujata, Gulati, Sheffali, Gupta, Neerja, Kabra, Madhulika, Scaria, Vinod, Sivasubbu, Sridhar

Publikováno v: In Mitochondrion March 2024 75

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De novo identification of viral pathogens from cell culture hologenomes

Autor: Patowary Ashok, Chauhan Rajendra, Singh Meghna, KV Shamsudheen, Periwal Vinita, KP Kushwaha, Sapkal Gajanand N, Bondre Vijay P, Gore Milind M, Sivasubbu Sridhar, Scaria Vinod

Publikováno v: BMC Research Notes, Vol 5, Iss 1, p 11 (2012)

Abstract Background Fast, specific identification and surveillance of pathogens is the cornerstone of any outbreak response system, especially in the case of emerging infectious diseases and viral epidemics. This process is generally tedious and time

Externí odkaz: https://doaj.org/article/168280be935c467dbb2de52eec9c9dfb

LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy.

Autor: Sehgal P; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Mathew S; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Sivadas A; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Ray A; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Tanwar J; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India.; Laboratory of Calciomics and Systemic Pathophysiology, Regional Center for Biotechnology, Faridabad, India., Vishwakarma S; Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India., Ranjan G; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Shamsudheen KV; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Bhoyar RC; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Pateria A; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Leonard E; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Lalwani M; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Vats A; CSIR-Institute of Genomics and Integrative Biology, Delhi, India., Pappuru RR; Kannuri Santhamma Centre for Retina and Vitreous, L V Prasad Eye Institute, Hyderabad, India., Tyagi M; Kannuri Santhamma Centre for Retina and Vitreous, L V Prasad Eye Institute, Hyderabad, India., Jakati S; Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India., Sengupta S; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., B K B; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Chakrabarti S; Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India., Kaur I; Brien Holden Eye Research Centre, L V Prasad Eye Institute, Hyderabad, India., Motiani RK; Laboratory of Calciomics and Systemic Pathophysiology, Regional Center for Biotechnology, Faridabad, India., Scaria V; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India., Sivasubbu S; CSIR-Institute of Genomics and Integrative Biology, Delhi, India.; Academy of Scientific and Innovative Research, Ghaziabad, India.

Publikováno v: The EMBO journal [EMBO J] 2021 Aug 02; Vol. 40 (15), pp. e107134. Date of Electronic Publication: 2021 Jun 28.

Maternal vitamin B 12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring.

Autor: Tanwar VS; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Ghosh S; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Sati S; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Ghose S; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Kaur L; CSIR-Centre for Cellular & Molecular Biology (CSIR-CCMB), Habsiguda, Uppal Road, Hyderabad, 500007, Telangana, India., Kumar KA; Endocrinology and Metabolism Division, National Institute of Nutrition (NIN), Uppal Road, Hyderabad, 500007, India., Shamsudheen KV; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Patowary A; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Singh M; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Jyothi V; CSIR-Centre for Cellular & Molecular Biology (CSIR-CCMB), Habsiguda, Uppal Road, Hyderabad, 500007, Telangana, India., Kommineni P; CSIR-Centre for Cellular & Molecular Biology (CSIR-CCMB), Habsiguda, Uppal Road, Hyderabad, 500007, Telangana, India., Sivasubbu S; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Scaria V; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Raghunath M; Endocrinology and Metabolism Division, National Institute of Nutrition (NIN), Uppal Road, Hyderabad, 500007, India., Mishra R; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.; CSIR-Centre for Cellular & Molecular Biology (CSIR-CCMB), Habsiguda, Uppal Road, Hyderabad, 500007, Telangana, India., Chandak GR; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. chandakgrc@ccmb.res.in.; CSIR-Centre for Cellular & Molecular Biology (CSIR-CCMB), Habsiguda, Uppal Road, Hyderabad, 500007, Telangana, India. chandakgrc@ccmb.res.in., Sengupta S; CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, Mathura Road, New Delhi, 110 020, India. shantanus@igib.res.in.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. shantanus@igib.res.in.

Publikováno v: Molecular and cellular biochemistry [Mol Cell Biochem] 2020 May; Vol. 468 (1-2), pp. 83-96. Date of Electronic Publication: 2020 Mar 18.