Zobrazeno 1 - 10
of 236
pro vyhledávání: '"KURT W. KOHN"'
Autor:
Camille Tlemsani, Lorinc Pongor, Fathi Elloumi, Luc Girard, Kenneth E. Huffman, Nitin Roper, Sudhir Varma, Augustin Luna, Vinodh N. Rajapakse, Robin Sebastian, Kurt W. Kohn, Julia Krushkal, Mirit I. Aladjem, Beverly A. Teicher, Paul S. Meltzer, William C. Reinhold, John D. Minna, Anish Thomas, Yves Pommier
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108296- (2020)
Summary: CellMiner-SCLC (https://discover.nci.nih.gov/SclcCellMinerCDB/) integrates drug sensitivity and genomic data, including high-resolution methylome and transcriptome from 118 patient-derived small cell lung cancer (SCLC) cell lines, providing
Externí odkaz:
https://doaj.org/article/c3a89008a1ef48f497155a5b22995bc3
Autor:
Vinodh N. Rajapakse, Augustin Luna, Mihoko Yamade, Lisa Loman, Sudhir Varma, Margot Sunshine, Francesco Iorio, Fabricio G. Sousa, Fathi Elloumi, Mirit I. Aladjem, Anish Thomas, Chris Sander, Kurt W. Kohn, Cyril H. Benes, Mathew Garnett, William C. Reinhold, Yves Pommier
Publikováno v:
iScience, Vol 10, Iss , Pp 247-264 (2018)
Summary: CellMinerCDB provides a web-based resource (https://discover.nci.nih.gov/cellminercdb/) for integrating multiple forms of pharmacological and genomic analyses, and unifying the richest cancer cell line datasets (the NCI-60, NCI-SCLC, Sanger/
Externí odkaz:
https://doaj.org/article/735107384b444a4dbe5dd2d94924a21a
Autor:
Yves Pommier, Manel Esteller, Paul S. Meltzer, James H. Doroshow, David J. Goldstein, Sebastian Moran, Vanesa Nogales, Holger Heyn, Yonghong Wang, Holly Stevenson, Kurt W. Kohn, Augustin Luna, Vinodh Rajapakse, Margot Sunshine, Sudhir Varma, William C. Reinhold
Methylation gene probe selection and correlation to expression level.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6bccb3c1506b57e4aef3d2cc1d6155
https://doi.org/10.1158/0008-5472.22416495
https://doi.org/10.1158/0008-5472.22416495
To organize the rapidly accumulating information on bioregulatory networks related to the histone γ-H2AX-ATM-Chk2-p53-Mdm2 pathways in concise and unambiguous diagrams, we used the molecular interaction map notation (http://discover.nci.nih.gov/min)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1cf2f762417912fd66511a3b753033
https://doi.org/10.1158/1078-0432.c.6518563
https://doi.org/10.1158/1078-0432.c.6518563
Supplementary Figure 5 from Chk2 Molecular Interaction Map and Rationale for Chk2 Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e5d4b36eb12b74af47af41320f886a
https://doi.org/10.1158/1078-0432.22441522.v1
https://doi.org/10.1158/1078-0432.22441522.v1
Supplementary Figure 4 from Chk2 Molecular Interaction Map and Rationale for Chk2 Inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c58b5f720e88c23d2f5707479af5e76
https://doi.org/10.1158/1078-0432.22441525.v1
https://doi.org/10.1158/1078-0432.22441525.v1
Autor:
Yves Pommier, Manel Esteller, Paul S. Meltzer, James H. Doroshow, David J. Goldstein, Sebastian Moran, Vanesa Nogales, Holger Heyn, Yonghong Wang, Holly Stevenson, Kurt W. Kohn, Augustin Luna, Vinodh Rajapakse, Margot Sunshine, Sudhir Varma, William C. Reinhold
Legends for Supplemental Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a930325eaf73460559a4316e088a851
https://doi.org/10.1158/0008-5472.22416498.v1
https://doi.org/10.1158/0008-5472.22416498.v1
Autor:
Yves Pommier, Manel Esteller, Paul S. Meltzer, James H. Doroshow, David J. Goldstein, Sebastian Moran, Vanesa Nogales, Holger Heyn, Yonghong Wang, Holly Stevenson, Kurt W. Kohn, Augustin Luna, Vinodh Rajapakse, Margot Sunshine, Sudhir Varma, William C. Reinhold
A unique resource for systems pharmacology and genomic studies is the NCI-60 cancer cell line panel, which provides data for the largest publicly available library of compounds with cytotoxic activity (∼21,000 compounds), including 108 FDA-approved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d71c0d120e3ca47091bb53966dcfda5
https://doi.org/10.1158/0008-5472.c.6509562.v1
https://doi.org/10.1158/0008-5472.c.6509562.v1
Autor:
Yves Pommier, Manel Esteller, Paul S. Meltzer, James H. Doroshow, David J. Goldstein, Sebastian Moran, Vanesa Nogales, Holger Heyn, Yonghong Wang, Holly Stevenson, Kurt W. Kohn, Augustin Luna, Vinodh Rajapakse, Margot Sunshine, Sudhir Varma, William C. Reinhold
Correlations between expression and DNA methylation for 17,144 transcripts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163d72840086b533cca66a95b0ab46af
https://doi.org/10.1158/0008-5472.22416486.v1
https://doi.org/10.1158/0008-5472.22416486.v1
Autor:
William C. Reinhold, Yves Pommier, John N. Weinstein, Kurt W. Kohn, Philip Lorenzi, Stephanie Fulmer-Smentek, Petula D'Andrade, Hongfang Liu
As part of the Spotlight on Molecular Profiling series, we present here new profiling studies of mRNA and microRNA expression for the 60 cell lines of the National Cancer Institute (NCI) Developmental Therapeutics program (DTP) drug screen (NCI-60) u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf0fdeabb82adf357af541b882a1005
https://doi.org/10.1158/1535-7163.c.6532136.v1
https://doi.org/10.1158/1535-7163.c.6532136.v1