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Akademický článek

Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae

Autor: Fernando Rodrigo Rosas Bringas, Sonia Stinus, Pien de Zoeten, Marita Cohn, Michael Chang

Publikováno v: eLife, Vol 11 (2022)

Rap1 is the main protein that binds double-stranded telomeric DNA in Saccharomyces cerevisiae. Examination of the telomere functions of Rap1 is complicated by the fact that it also acts as a transcriptional regulator of hundreds of genes and is encod

Externí odkaz: https://doaj.org/article/b91212b501214980ad575916b57b23ca

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Functions and regulation of the MRX and Ku protein complexes at DNA ends

Autor: RINALDI, CARLO

L'instabilità del genoma è una delle caratteristiche delle cellule tumorali e può essere causata da difetti nella riparazione del DNA. In particolare, le rotture del doppio filamento del DNA (DSBs) sono lesioni altamente citotossiche che possono f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1299::11d4190d9e7b32341973917e97e709e4
https://hdl.handle.net/10281/402372

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Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae

Autor: Michael Chang, Pien de Zoeten, Marita Cohn, Sonia Stinus, Fernando Rosas Bringas

Publikováno v: eLife. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 11 (2022)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9b864d91a33c2fda9bd8cc9901f750
https://doi.org/10.7554/elife.74090

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Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in

Autor: Fernando Rodrigo, Rosas Bringas, Sonia, Stinus, Pien, de Zoeten, Marita, Cohn, Michael, Chang

Publikováno v: eLife

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d59f230269cce4799ceb91faefa76ea8
https://pubmed.ncbi.nlm.nih.gov/35044907

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Ku complex suppresses recombination in the absence of MRX activity during budding yeast meiosis

Autor: Keunpil Kim, Hyeseon Yun

Publikováno v: BMB Reports

During meiosis, programmed double-strand breaks (DSBs) are repaired via recombination pathways that are required for faithful chromosomal segregation and genetic diversity. In meiotic progression, the non-homologous end joining (NHEJ) pathway is supp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f551a1bb32c533d3141ec196781a7e54
https://doi.org/10.5483/bmbrep.2019.52.10.245

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Suppression of cdc13-2-associated senescence by pif1-m2 requires Ku-mediated telomerase recruitment

Autor: Michael Chang, Fernando R. Rosas Bringas, Sonia Stinus, Enikő Fekete-Szücs

Publikováno v: bioRxiv. Cold Spring Harbor Labs Journals
bioRxiv
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
G3: Genes|Genomes|Genetics
G3 Genes|Genomes|Genetics, 12(1). GENETICS SOCIETY AMERICA

In Saccharomyces cerevisiae, recruitment of telomerase to telomeres requires an interaction between Cdc13, which binds single-stranded telomeric DNA, and the Est1 subunit of telomerase. A second pathway involving an interaction between the yKu comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cfba8a1f89b18800d346cc5b10989f
https://research.rug.nl/en/publications/11065f4f-5bc6-4d5d-9bc6-df2522ee5781

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A uniform expression library for the exploration of FOX transcription factor biology

Autor: Stefan Koch, Lavanya Moparthi

Forkhead box (FOX) family transcription factors play essential roles in development, tissue homeostasis, and disease. Although the biology of several FOX proteins has been studied in depth, it is unclear to what extent these findings apply to even cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0748be312ebc43a4624994eb352ef3f3
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-168954

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