Zobrazeno 1 - 10
of 368
pro vyhledávání: '"KT5720"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Platelets. 33:859-868
Cyclic nucleotides (cAMP and cGMP) and corresponding protein kinases, protein kinase A (PKA) and protein kinase G (PKG), are the main intracellular mediators of endothelium-derived platelet inhibitors. Pharmacological PKA/PKG inhibitors are often use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4082806ce41fc9f0a077cce07e3d7b3
https://doi.org/10.1080/09537104.2021.2003316
https://doi.org/10.1080/09537104.2021.2003316
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Carbon monoxide (CO) is a cardioprotectant and potential cardiovascular therapeutic agent. Human cardiac fibroblasts (HCFs) are important determinants of myocardial structure and function. Large-conductance Ca2+-activated K+ (BK) channel is a potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55386f18772fb61369d9898c1df1a52c
https://doi.org/10.4196/kjpp.2021.25.3.227
https://doi.org/10.4196/kjpp.2021.25.3.227
Publikováno v:
Cardiovascular Toxicology. 21:422-431
Rosuvastatin is one of the most used statins to lower plasma cholesterol levels. Although previous studies have reported remarkable cardiovascular effects of rosuvastatin (RSV), the mechanisms of these effects are largely unknown. In this study, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ccc16a45abfc0d0966e1a0181b1197
https://doi.org/10.1007/s12012-021-09642-5
https://doi.org/10.1007/s12012-021-09642-5
Publikováno v:
International Archives of Allergy and Immunology. 182:800-806
Background: The ciliary beat of the airway epithelium, including the sinonasal epithelium, has a significant role in frontline defense and is thought to be controlled by the level of intracellular Ca2+. Involvement of calmodulin and adenylate/guanyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4a483ce57f878ee102a39ba6905c92
https://doi.org/10.1159/000515225
https://doi.org/10.1159/000515225
Autor:
Kremena E. Saracheva, Vera N Gledacheva, Darinka Slavcheva Dimitrova, Atanas D Kristev, Iliyana D. Stefanova, Stoyanka Nikolova, Valeri I. Slavchev, Rayna G Ardasheva
Publikováno v:
Folia Medica, Vol 62, Iss 3, Pp 532-538 (2020)
Introduction: Examination of the potential possibilities of 2-chloro-N-(1-(3,4-dimethoxyphenyl)propan-2-yl)-2-phenylacetamide (IQP) to affect bioelectrogenesis and the contractile activity of isolated smooth muscles (SM) from stomach. Aim: Having in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f537ae2a9a3aca2188277d28b85267d
https://doi.org/10.3897/folmed.62.e47844
https://doi.org/10.3897/folmed.62.e47844
Publikováno v:
Biology of Reproduction
Biology of Reproduction, Society for the Study of Reproduction, 2020, 102 (6), pp.1290-1305. ⟨10.1093/biolre/ioaa027⟩
Biology of Reproduction, Society for the Study of Reproduction, 2020, 102 (6), pp.1290-1305. ⟨10.1093/biolre/ioaa027⟩
Vaspin, visceral-adipose-tissue-derived serine protease inhibitor, is involved in the development of obesity, insulin resistance, inflammation, and energy metabolism. Our previous study showed vaspin expression and its regulation in the ovary; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c497a34eed66659197c601069332ec8
https://doi.org/10.1093/biolre/ioaa027
https://doi.org/10.1093/biolre/ioaa027
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 47:16-26
We characterised the voltage-gated Ca2+ channels (VGCCs) in human cardiac fibroblasts (HCFs) and myofibroblasts (HCMFs) and investigated the effects of nitric oxide (NO) on apoptosis and on these channels. Western blotting and immunofluorescence anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73a83bb029abc030959b407dedd7dfe
https://doi.org/10.1111/1440-1681.13178
https://doi.org/10.1111/1440-1681.13178
Autor:
Thi Nga Nguyen, Toyoaki Ohbuchi, Takuro Kitamura, Ryoko Baba, Hiroyuki Morimoto, Hideaki Suzuki, Tetsuro Wakasugi, Jun-ichi Ohkubo, Ba Hung Do
Publikováno v:
International Forum of Allergy & Rhinology. 9:1352-1359
Background Mucociliary clearance of the airway epithelium is an essential function for mucosal defense. We recently proposed a hypothetical mechanism of ciliary beat regulation, in which the pannexin-1 (Panx1)-P2X7 unit serves as an oscillator genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da663e3567abbcd0b206fcf4321344c3
https://doi.org/10.1002/alr.22442
https://doi.org/10.1002/alr.22442
Autor:
Héctor Zapata-Carmona, Lidia M. Zuñiga, Patricio Morales, Erma Z. Drobnis, Milene Kong, Emilce S. Diaz, Lina Barón, Peter Sutovsky
Publikováno v:
Mol Hum Reprod
One of the first events of mammalian sperm capacitation is the activation of the soluble adenyl cyclase/cAMP/protein kinase A (SACY/cAMP/PKA) pathway. Here, we evaluated whether the increase in PKA activity at the onset of human sperm capacitation is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285316f2ebb1465c54711cbc704ff0de
https://doi.org/10.1093/molehr/gaz037
https://doi.org/10.1093/molehr/gaz037