Zobrazeno 1 - 10
of 99
pro vyhledávání: '"KRAS G12C mutation"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Lung cancer remains a significant health challenge, characterized by aberrant tissue growth within the pulmonary system. Early carcinogenic events often involve genomic instability and the emergence of a mutator phenotype. In this study, we
Externí odkaz:
https://doaj.org/article/0db7784893b04f35bcd86368efa78a37
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 4507-4517 (2024)
Yawan Jing,1,2 Ruixin Cheng,3 Hao Zeng,1 Qin Huang,1 Dongyu He,1 Jiayi Sun,1 Panwen Tian,1,4 Yalun Li1,4 1Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Heal
Externí odkaz:
https://doaj.org/article/61874a4feed143d3bb42c30cd01c1643
Publikováno v:
Current Problems in Cancer: Case Reports, Vol 14, Iss , Pp 100291- (2024)
In the last few years, non-small cell lung cancer (NSCLC) treatment has totally revolutionized by the improvement in molecular diagnostics and the introduction of targeted therapies, becoming the standard of care in patients with actionable alteratio
Externí odkaz:
https://doaj.org/article/30d1a6c3f25f4f92af1b5d2c31fefd6d
Autor:
Lei-Lei Wu, Wen-Mei Jiang, Zhi-Yuan Liu, Yi-Yi Zhang, Jia-Yi Qian, Yu’e Liu, Yang-Yu Huang, Kun Li, Zhi-Xin Li, Guo-Wei Ma, Dong Xie
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background The efficacy of monotherapy of AMG-510 is limited. This study explored whether the AMG-510 and cisplatin combination increases the anti-tumor effect in lung adenocarcinoma with the mutation of Kirsten rat sarcoma viral oncogene (K
Externí odkaz:
https://doaj.org/article/01f33144faf6435d8ceb20f40eb096e5
Autor:
Masafumi Saiki, MD, Chisa Omori, MD, Honami Morikawa, MD, Ken Shinohara, MD, So Shimamura, MD, Hiroki Ohkoshi, MD, Yoshinori Uchida, MD, Tomohiro Inoue, MD, PhD, Tetsuo Kondo, MD, PhD, Shinnosuke Ikemura, MD, PhD, Kenzo Soejima, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 1, Pp 100620- (2024)
Pulmonary neuroendocrine tumors are rare, accounting for approximately 1% to 2% of lung cancers. Atypical carcinoids account for approximately 10% of pulmonary neuroendocrine tumors and are categorized as moderately malignant. Treatment options for a
Externí odkaz:
https://doaj.org/article/ed3451181a674e7c9a4e8c0d59648074
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
KRAS G12C mutations are critical in the pathogenesis of multiple cancer types, including non-small cell lung (NSCLC), pancreatic ductal adenocarcinoma (PDAC), and colorectal (CRC) cancers. As such, they have increasingly become a target of novel ther
Externí odkaz:
https://doaj.org/article/0123c7203f9a48e09779ce429e681466
Akademický článek
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Autor:
Kohei Okada, Rie Sakakibara, Takayuki Honda, Takahiro Mitsumura, Sho Shibata, Tsuyoshi Shirai, Tsukasa Okamoto, Haruhiko Furusawa, Tomoya Tateishi, Yasunari Miyazaki
Publikováno v:
Respiratory Medicine Case Reports, Vol 46, Iss , Pp 101929- (2023)
A 74-year-old man was referred to our hospital with an abnormal chest shadow. Computed tomography (CT) revealed a mass in the left upper lobe and interstitial pneumonia (IP). The patient underwent CT-guided needle biopsy and was diagnosed as lung ade
Externí odkaz:
https://doaj.org/article/005d6241cc6b4f9b8667b84218770c05
Autor:
Kei Kunimasa, MD, PhD, Motohiro Tamiya, MD, Takako Inoue, MD, Takahisa Kawamura, MD, PhD, Kazumi Nishino, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 1, Pp 100442- (2023)
The efficacy of sotorasib for patients with KRAS G12C-mutated lung cancer with poor performance status (PS) and active brain metastases remains unknown. Here, we present a case in which sotorasib was introduced as the third-line therapy for a patient
Externí odkaz:
https://doaj.org/article/6c4f9b81137c4405a6bf4b860c9d8bb6
Akademický článek
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