Zobrazeno 1 - 10
of 154
pro vyhledávání: '"KR Harrap"'
Autor:
Mj Abrams, Cfj Barnard, Lr Kelland, M Jones, Jj Gwynne, Cm Giandomenico, Jf Vollano, Kr Harrap, M Valenti, Ba Murrer
Publikováno v:
International journal of oncology. 2(6)
The antitumour activity of a series of ten novel ammine/amine platinum (IV) dicarboxylates of general formula [Pt(IV) Cl2 (OCOR1) NH3 (RNH2)] where R1 was an aliphatic or aromatic substituent and R an aliphatic or alicyclic substituent, was evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b0aaea2f662f08ece07c36f4a07b8d
https://pubmed.ncbi.nlm.nih.gov/21573668
https://pubmed.ncbi.nlm.nih.gov/21573668
1 Chlorambucil (10 mg) and prednimustine (20 mg), the prednisolone ester of chlorambucil, were administered orally on separate occasions to six patients. 2 Chlorambucil was rapidly absorbed such that the parent compound was observed in the plasma 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275614f4bbd3cfce93936037d936f2cc
https://europepmc.org/articles/PMC1427847/
https://europepmc.org/articles/PMC1427847/
Publikováno v:
Cancer treatment reviews. 12
Carboplatin was evaluated in a Phase I and pharmacokinetic study at the Royal Marsden Hospital between April 1981 and November 1981. Sixty patients were entered of whom 16 had impaired renal function. No evidence of ototoxicity or nephrotoxicity was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c290f10ac41cbe979a162e3a483914c3
https://pubmed.ncbi.nlm.nih.gov/3910222
https://pubmed.ncbi.nlm.nih.gov/3910222
Autor:
Ah, Calvert, Dr, Newell, Al, Jackman, La, Gumbrell, Ewa Sikora, Grzelakowska-Sztabert B, Ja, Bishop, Ir, Judson, Sj, Harland, Kr, Harrap
Publikováno v:
Europe PubMed Central
CB 3717, N10-propargyl-5,8-dideazafolic acid, is a tight-binding inhibitor of thymidylate synthase (TS) whose cytotoxicity is mediated solely through the inhibition of this enzyme. Recent preclinical studies have focused on the intracellular formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::827f43a1778de323831883c55832e60f
https://pubmed.ncbi.nlm.nih.gov/3431591
https://pubmed.ncbi.nlm.nih.gov/3431591
Publikováno v:
British Journal of Clinical Pharmacology. 16:762-763
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feb9b974be4d9d93c9955d709582286a
https://doi.org/10.1111/j.1365-2125.1983.tb02264.x
https://doi.org/10.1111/j.1365-2125.1983.tb02264.x
Autor:
Leyland-Jones B; Department of Oncology, McGill University, Montreal, Quebec, Canada. leylandj@med.mcgill.ca, Kelland LR, Harrap KR, Hiorns LR
Publikováno v:
The American journal of pathology [Am J Pathol] 1999 Jul; Vol. 155 (1), pp. 77-84.
Autor:
McKeage MJ; Cancer Research Campaign Centre of Cancer Therapeutics, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom., Raynaud F, Ward J, Berry C, O'Dell D, Kelland LR, Murrer B, Santabárabara P, Harrap KR, Judson IR
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 1997 Jul; Vol. 15 (7), pp. 2691-700.
Autor:
Ormerod MG; Cancer Research Campaign Centre for Cancer Therapeutics, Institute of Cancer Research: Royal Cancer Hospital, Sutton, UK., Orr RM, O'Neill CF, Chwalinski T, Titley JC, Kelland LR, Harrap KR
Publikováno v:
British journal of cancer [Br J Cancer] 1996 Dec; Vol. 74 (12), pp. 1935-43.
Autor:
Clarke SJ; Institute of Cancer Research, Sutton, Surrey, United Kingdom., Hanwell J, de Boer M, Planting A, Verweij J, Walker M, Smith R, Jackman AL, Hughes LR, Harrap KR, Kennealey GT, Judson IR
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 1996 May; Vol. 14 (5), pp. 1495-503.
Autor:
Ormerod MG; Cancer Research Campaign Centre For Cancer Therapeutics, Institute of Cancer Research, Royal Cancer Hospital, Sutton, UK., O'Neill C, Robertson D, Kelland LR, Harrap KR
Publikováno v:
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 1996; Vol. 37 (5), pp. 463-71.