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A Small Molecule RIG-I Agonist Serves as an Adjuvant to Induce Broad Multifaceted Influenza Virus Vaccine Immunity.

Autor: Hemann EA; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA.; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH., Knoll ML; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA., Wilkins CR; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA., Subra C; The Henry M. Jackson Foundation for the Advancement of Military Medicine and the U.S. Military HIV Research Program, Bethesda, MD., Green R; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA., García-Sastre A; The Henry M. Jackson Foundation for the Advancement of Military Medicine and the U.S. Military HIV Research Program, Bethesda, MD.; Department of Microbiology, The Tisch Cancer Institute, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY.; Department of Pathology, Molecular and Cell-Based Medicine, The Tisch Cancer Institute, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY., Thomas PG; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN., Trautmann L; The Henry M. Jackson Foundation for the Advancement of Military Medicine and the U.S. Military HIV Research Program, Bethesda, MD.; Vaccine and Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR., Ireton RC; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA., Loo YM; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA., Gale M Jr.; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 May 01; Vol. 210 (9), pp. 1247-1256.

SARS-CoV-2 Serologic Assays in Control and Unknown Populations Demonstrate the Necessity of Virus Neutralization Testing.

Autor: Rathe JA; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Pediatric Infectious Disease, Seattle Children's Hospital/University of Washington, Seattle, Washington, USA., Hemann EA; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Eggenberger J; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Li Z; Department of Statistics, University of Washington, Seattle, Washington, USA., Knoll ML; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Stokes C; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.; Department of Pediatric Infectious Disease, Seattle Children's Hospital/University of Washington, Seattle, Washington, USA., Hsiang TY; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Netland J; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Takehara KK; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Pepper M; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Gale M Jr; Department of Immunology, Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2021 Apr 08; Vol. 223 (7), pp. 1120-1131.

Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway.

Autor: Pattabhi S; Department of Global Health, University of Washington, Seattle, Washington, USA., Wilkins CR; Department of Immunology, University of Washington, Seattle, Washington, USA Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Dong R; Department of Immunology, University of Washington, Seattle, Washington, USA., Knoll ML; Department of Immunology, University of Washington, Seattle, Washington, USA Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Posakony J; Kineta, Inc., Seattle, Washington, USA., Kaiser S; Kineta, Inc., Seattle, Washington, USA., Mire CE; University of Texas Medical Branch at Galveston, Galveston National Laboratory, Galveston, Texas, USA., Wang ML; Kineta, Inc., Seattle, Washington, USA., Ireton RC; Department of Immunology, University of Washington, Seattle, Washington, USA Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA., Geisbert TW; University of Texas Medical Branch at Galveston, Galveston National Laboratory, Galveston, Texas, USA., Bedard KM; Kineta, Inc., Seattle, Washington, USA., Iadonato SP; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA Kineta, Inc., Seattle, Washington, USA., Loo YM; Department of Immunology, University of Washington, Seattle, Washington, USA Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA looy@uw.edu mgale@uw.edu., Gale M Jr; Department of Global Health, University of Washington, Seattle, Washington, USA Department of Immunology, University of Washington, Seattle, Washington, USA Center for Innate Immunity and Immune Disease, University of Washington, Seattle, Washington, USA looy@uw.edu mgale@uw.edu.

Publikováno v: Journal of virology [J Virol] 2015 Dec 16; Vol. 90 (5), pp. 2372-87. Date of Electronic Publication: 2015 Dec 16.