Zobrazeno 1 - 10
of 631
pro vyhledávání: '"KNIME"'
Autor:
José T. Moreira-Filho, Dhruv Ranganath, Mike Conway, Charles Schmitt, Nicole Kleinstreuer, Kamel Mansouri
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-27 (2024)
Abstract With the increased availability of chemical data in public databases, innovative techniques and algorithms have emerged for the analysis, exploration, visualization, and extraction of information from these data. One such technique is chemic
Externí odkaz:
https://doaj.org/article/4e06f021754148c3877a42c8c5c607f5
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34462- (2024)
Plant-derived natural compounds are significant resources for the discovery of potential anticancer drugs. While research in the plant-based anticancer field has surged in recent years, systematic bibliometric analyses covering a longer period and co
Externí odkaz:
https://doaj.org/article/f13826d1d95042b5ae867618e9d4254d
Autor:
Daniela Digles, Alvaro Ingles-Prieto, Vojtech Dvorak, Tamara A. M. Mocking, Ulrich Goldmann, Andrea Garofoli, Evert J. Homan, Alberto Di Silvio, Lucia Azzollini, Francesca Sassone, Mario Fogazza, Felix Bärenz, Antje Pommereau, Yasmin Zuschlag, Jasper F. Ooms, Jeppe Tranberg-Jensen, Jesper S. Hansen, Josefina Stanka, Hubert J. Sijben, Helena Batoulis, Eckhard Bender, Riccardo Martini, Adriaan P. IJzerman, David B. Sauer, Laura H. Heitman, Vania Manolova, Juergen Reinhardt, Alexander Ehrmann, Philipp Leippe, Gerhard F. Ecker, Kilian V. M. Huber, Thomas Licher, Lia Scarabottolo, Tabea Wiedmer, Giulio Superti-Furga
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
With over 450 genes, solute carriers (SLCs) constitute the largest transporter superfamily responsible for the uptake and efflux of nutrients, metabolites, and xenobiotics in human cells. SLCs are associated with a wide variety of human diseases, inc
Externí odkaz:
https://doaj.org/article/d3ca8f18dbc2476ea3722a966b570ca6
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Membrane permeability is an in vitro parameter that represents the apparent permeability (Papp) of a compound, and is a key absorption, distribution, metabolism, and excretion parameter in drug development. Although the Caco-2 cell lines are
Externí odkaz:
https://doaj.org/article/2bcbc21b9dbd471cbd991451510adb17
Autor:
Kamel Mansouri, José T. Moreira-Filho, Charles N. Lowe, Nathaniel Charest, Todd Martin, Valery Tkachenko, Richard Judson, Mike Conway, Nicole C. Kleinstreuer, Antony J. Williams
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract The rapid increase of publicly available chemical structures and associated experimental data presents a valuable opportunity to build robust QSAR models for applications in different fields. However, the common concern is the quality of bot
Externí odkaz:
https://doaj.org/article/ca62db38853a477f8e316d435cd15cb9
Publikováno v:
Information, Vol 15, Iss 10, p 625 (2024)
Automated Machine Learning (AutoML) enhances productivity and efficiency by automating the entire process of machine learning model development, from data preprocessing to model deployment. These tools are accessible to users with varying levels of e
Externí odkaz:
https://doaj.org/article/9ece926fd70b4301853a8a27e89d15ed
Autor:
Lingbo Liu, Fahui Wang, Xiaokang Fu, Tobias Kötter, Kevin Sturm, Weihe Wendy Guan, Shuming Bao
Publikováno v:
International Journal of Applied Earth Observations and Geoinformation, Vol 130, Iss , Pp 103948- (2024)
Reproducibility, replicability, and expandability (RRE) have emerged as fundamental concerns in the realm of scientific research and development. Wherein, devising effective solutions for RRE within geospatial analysis stands out as a particularly cr
Externí odkaz:
https://doaj.org/article/ac37b7e191c3445896669e0dcee152cf
Autor:
Ruchira Joshi, Zipeng Zheng, Palak Agarwal, Ma’mon M. Hatmal, Xinmin Chang, Paul Seidler, Ian S. Haworth
Publikováno v:
Artificial Intelligence Chemistry, Vol 2, Iss 1, Pp 100063- (2024)
Artificial intelligence (AI) has huge potential to accelerate drug discovery, but challenges remain in implementing AI algorithms that can be used by the broad scientific community. Identification of molecular features and their subsequent use in tra
Externí odkaz:
https://doaj.org/article/224523efe41347cb88090117711fb668
Autor:
D. V. Minaev
Publikováno v:
Управленческое консультирование, Vol 0, Iss 10, Pp 45-68 (2023)
The general logic of the formation of competence models in the interaction of labor market subjects and vocational education institutions is analyzed. Possible gaps in the sequential deployment of competency models along the chain “profession — p
Externí odkaz:
https://doaj.org/article/bf78ed9a5af8458ea26aab8ef0a518c9
Autor:
Mousumi Saha, Saptarshi Ghosh
Publikováno v:
International Journal of Information Science and Management, Vol 21, Iss 3, Pp 19-34 (2023)
This paper portrays the topic modeling approach in identifying critical facets in new Library and Information Science (LIS) research. Using machine language, topic modeling in statistics recognizes the "topics" in a document pool. Latent Dirichlet Al
Externí odkaz:
https://doaj.org/article/9848ac4ed50348ebb719ae20937775a0