Innate immune cell activation by adjuvant AS01 in human lymph node explants is age independent.

Autor: Stylianou VV; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Bertram KM; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Vo VA; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Dunn EB; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Baharlou H; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Terre DJ; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Elhindi J; Research and Education Network, Western Sydney Local Health District, Westmead, New South Wales, Australia., Elder E; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; The Westmead Breast Cancer Institute, Westmead, New South Wales, Australia., French J; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; The Westmead Breast Cancer Institute, Westmead, New South Wales, Australia., Meybodi F; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; The Westmead Breast Cancer Institute, Westmead, New South Wales, Australia., Temmerman ST; GSK, Rixensart, Belgium., Didierlaurent AM; Center of Vaccinology, Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Coccia M; GSK, Rixensart, Belgium., Sandgren KJ; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Cunningham AL; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Sep 24; Vol. 134 (22). Date of Electronic Publication: 2024 Sep 24.

Herpes simplex virus spreads rapidly in human foreskin, partly driven by chemokine-induced redistribution of Nectin-1 on keratinocytes.

Autor: Rana H; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Truong NR; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Johnson B; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Baharlou H; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Herbert JJ; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Kandasamy S; Research and Development, Vaxxas Pty Ltd., Brisbane, Queensland, Australia., Goddard R; Research and Development, Vaxxas Pty Ltd., Brisbane, Queensland, Australia., Cohen RC; University of Sydney and Australian National University, Children's Hospital at Westmead, New South Wales, Australia., Wines M; Urology, Sydney Adventist Hospital, Wahroonga, New South Wales, Australia., Nasr N; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Harman AN; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Bertram KM; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Sandgren KJ; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Cunningham AL; The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Jun 10; Vol. 20 (6), pp. e1012267. Date of Electronic Publication: 2024 Jun 10 (Print Publication: 2024).

Highly Networked SARS-CoV-2 Peptides Elicit T Cell Responses with Enhanced Specificity.

Autor: Duette G; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Lee E; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Martins Costa Gomes G; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia., Tungatt K; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia., Doyle C; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Stylianou VV; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Lee A; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia., Maddocks S; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia., Taylor J; Centre for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Westmead, New South Wales, Australia., Khanna R; QIMR Berghofer Centre for Immunotherapy and Vaccine Development, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Bull RA; School of Medical Sciences, Faculty of Medicine, UNSW Australia, Sydney, New South Wales, Australia.; The Kirby Institute, UNSW Australia, Sydney, New South Wales, Australia., Martinello M; The Kirby Institute, UNSW Australia, Sydney, New South Wales, Australia.; Westmead Hospital, Sydney, New South Wales, Australia.; Blacktown & Mount Druitt Hospital, Blacktown, New South Wales, Australia., Sandgren KJ; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Cunningham AL; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Palmer S; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Publikováno v: ImmunoHorizons [Immunohorizons] 2023 Jun 01; Vol. 7 (6), pp. 508-527.

An in situ analysis pipeline for initial host-pathogen interactions reveals signatures of human colorectal HIV transmission.

Autor: Baharlou H; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia. Electronic address: heeva.baharlou@gmail.com., Canete N; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Vine EE; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Hu K; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Yuan D; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Sandgren KJ; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Bertram KM; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Nasr N; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Rhodes JW; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Gosselink MP; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Di Re A; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Reza F; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Ctercteko G; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Pathma-Nathan N; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Collins G; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Toh J; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; Department of Colorectal Surgery, Westmead Hospital, Westmead, NSW 2145, Australia., Patrick E; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Maths and Statistics, Faculty of Science, Sydney, NSW, Australia., Haniffa MA; Biosciences Institute, The University of Newcastle, Newcastle upon Tyne, UK; Wellcome Sanger Institute, Hinxton, UK; Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Estes JD; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Portland, OR, USA; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Portland, OR, USA., Byrne SN; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Cunningham AL; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia., Harman AN; Centre for Virus Research, The Westmead Institute for Medical Research, 176 Hawkesbury Road, Westmead, NSW 2145, Australia; The University of Sydney, School of Medical Sciences, Faculty of Medicine and Health Sydney, Sydney, NSW, Australia. Electronic address: andrew.harman@sydney.edu.au.

Publikováno v: Cell reports [Cell Rep] 2022 Sep 20; Vol. 40 (12), pp. 111385.

Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathways.

Autor: Bertram KM; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Truong NR; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Smith JB; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Kim M; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Sandgren KJ; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Feng KL; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Herbert JJ; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Rana H; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Danastas K; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Miranda-Saksena M; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Rhodes JW; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia., Patrick E; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The School of Mathematics and Statistics, Faculty of Science, The University of Sydney, Camperdown, Australia., Cohen RC; Department of Surgery, University of Sydney and The Children's Hospital at Westmead, Westmead, Australia., Lim J; Department of Surgery, Westmead Private Hospital, Westmead, Australia., Merten SL; Department of Surgery, Macquarie University Hospital, Macquarie Park, Australia., Harman AN; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Westmead, Australia., Cunningham AL; Centre for Virus Research, The Westmead Institute for Medical Research, Westmead, Australia.; The Westmead Clinical School, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Apr 27; Vol. 17 (4), pp. e1009536. Date of Electronic Publication: 2021 Apr 27 (Print Publication: 2021).