Zobrazeno 1 - 10
of 313
pro vyhledávání: '"KIYOAKI TSUKAHARA"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 966-972 (2024)
Introduction: Immune-related adverse events (irAEs) from nivolumab can affect any organ, but renal impairment is less common than effects on other organs. We encountered a case in which a renal irAE was difficult to diagnose due to mild renal dysfunc
Externí odkaz:
https://doaj.org/article/dbc979ba0f524722bd33649ea400481f
Autor:
Takahiro Tsujikawa, Kazuchika Ohno, Kei-ichi Morita, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Hiroshi Ogi, Saya Shibata, Takumi Akashi, Morito Kurata, Issei Imoto, Yasushi Shimizu, Satoshi Kano, Akihito Watanabe, Tomoko Yamazaki, Yukinori Asada, Ryuichi Hayashi, Yuki Saito, Hiroyuki Ozawa, Kiyoaki Tsukahara, Nobuhiko Oridate, Daisuke Sano, Arata Horii, Yushi Ueki, Takashi Maruo, Nobuaki Mukoyama, Nobuhiro Hanai, Takahito Fukusumi, Hiroshi Iwai, Takuo Fujisawa, Takashi Fujii, Ken-ichi Nibu, Shigemichi Iwae, Tsutomu Ueda, Nobuyuki Chikuie, Ryuji Yasumatsu, Mioko Matsuo, Hirohito Umeno, Takeharu Ono, Muneyuki Masuda, Satoshi Toh, Kyoko Itoh, Shigeru Hirano, Takahiro Asakage
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn view of improving biomarkers predicting the efficacy of immunotherapy for head and neck squamous cell carcinoma (R/M HNSCC), this multicenter retrospective study aimed to identify clinical, tumor microenvironmental, and genomic factors t
Externí odkaz:
https://doaj.org/article/b5c525023e134051b6b1b1fa136b47f3
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 180-185 (2024)
Introduction: Head and neck photoimmunotherapy (HN-PIT) uses a combination of drugs and laser illumination to specifically destroy tumor cells. Lemierre’s syndrome is an infectious disease with severe systemic symptoms caused by prior infection in
Externí odkaz:
https://doaj.org/article/0ef4d409bef64b77b2dbea37311dfcec
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 169-174 (2024)
Introduction: Head and neck photoimmunotherapy (HN-PIT) has been conditionally approved by the Japanese government for the treatment of unresectable locally advanced or locally recurrent head and neck cancer since January 2021. HN-PIT makes local tre
Externí odkaz:
https://doaj.org/article/71e0d00c0eb64131919f3ebe9d859e20
Autor:
Teruhisa Yano, Ryota Tomioka, Taro Inagaki, Ryo Akai, Keitaro Miyake, Sayaka Arai, Kiyoaki Tsukahara
Publikováno v:
SAGE Open Medical Case Reports, Vol 12 (2024)
Malignant otitis externa (skull base osteomyelitis) can be fatal and long-term antibiotic therapy is recommended. Despite being potentially fatal, this infection causes minor changes in inflammatory biomarkers (white blood cell count and C-reactive p
Externí odkaz:
https://doaj.org/article/ecc4028eb38e4d409db2076ab36ce976
Autor:
Chihiro Fushimi, Hideaki Takahashi, Daisuke Kawakita, Satoshi Kano, Kiyoaki Tsukahara, Hiroyuki Ozawa, Kenji Okami, Akihiro Sakai, Keisuke Yamazaki, Takuro Okada, Toyoyuki Hanazawa, Yuichiro Sato, Yorihisa Imanishi, Akira Shimizu, Takashi Matsuki, Toshitaka Nagao, Yuichiro Tada
Publikováno v:
Cancer Medicine, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Background Salivary duct carcinoma (SDC) is a high‐grade adenocarcinoma with a 5‐year survival rate of 40%. Although drug therapy has improved patients' prognosis, the impact of brain metastasis (BM) remains poorly understood. We aimed t
Externí odkaz:
https://doaj.org/article/15d1e28de5a0440e94de49f5d8890cef
A Case of Oropharyngeal Carcinoma with an Oblique Neck that Benefited from Transoral Robotic Surgery
Autor:
Tatsuya Yamakura, Akira Shimizu, Isaku Okamoto, Takuro Okada, Kunihiko Tokashiki, Takuma Kishida, Tatsuya Ito, Kiyoaki Tsukahara
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 930-934 (2023)
Transoral robotic surgery (TORS) and transoral videolaryngoscopic surgery (TOVS) are minimally invasive procedures for early-stage head and neck cancers. However, due to its unique nature, transoral resection often leads to skeletal and anatomical di
Externí odkaz:
https://doaj.org/article/05578e7a8dce4eabb580a71d01e00d37
Autor:
Takashi Matsuzuka, Kiyoaki Tsukahara, Seiichi Yoshimoto, Kazuaki Chikamatsu, Akihiro Shiotani, Isao Oze, Yoshiko Murakami, Takeshi Shinozaki, Yuichiro Enoki, Shinichi Ohba, Daisuke Kawakita, Nobuhiro Hanai, Yusuke Koide, Michi Sawabe, Yusuke Nakata, Yujiro Fukuda, Daisuke Nishikawa, Gaku Takano, Takahiro Kimura, Keisuke Oguri, Hitoshi Hirakawa, Yasuhisa Hasegawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract This sentinel node (SN) biopsy trial aimed to assess its effectiveness in identifying predictive factors of micrometastases and to determine whether elective neck dissection is necessary in oral squamous cell carcinoma. This retrospective st
Externí odkaz:
https://doaj.org/article/b214fa17c81b46239647ba5b2177ae8c
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Lysosomes are single-membraned organelles that mediate the intracellular degradation of macromolecules. Various stress can induce lysosomal membrane permeabilization (LMP), translocating intralysosomal components, such as cathepsins, to the
Externí odkaz:
https://doaj.org/article/9e6edb9a15e24e839ad03cd07c6712da
Autor:
Shinji Kohsaka, Yuichiro Tada, Mizuo Ando, Masato Nakaguro, Yukina Shirai, Toshihide Ueno, Shinya Kojima, Hideaki Hirai, Natsuki Saigusa, Satoshi Kano, Kiyoaki Tsukahara, Takafumi Togashi, Hiroyuki Ozawa, Takahito Kondo, Kenji Okami, Hideaki Takahashi, Daisuke Kawakita, Chihiro Fushimi, Takayoshi Suzuki, Akira Shimizu, Isaku Okamoto, Takuro Okada, Yuichiro Sato, Yorihisa Imanishi, Yoshihiro Watanabe, Akihiro Sakai, Koji Ebisumoto, Yukiko Sato, Makoto Urano, Yoshitaka Honma, Keisuke Yamazaki, Yushi Ueki, Toyoyuki Hanazawa, Yuki Saito, Tomotaka Shimura, Toshitaka Nagao, Hiroyuki Mano
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-12 (2022)
Abstract Molecular targets and predictive biomarkers for prognosis in salivary duct carcinoma (SDC) have not been fully identified. We conducted comprehensive molecular profiling to discover novel biomarkers for SDC. A total of 67 SDC samples were ex
Externí odkaz:
https://doaj.org/article/55457a756c094554a6dc1105eb124504