Zobrazeno 1 - 10
of 516
pro vyhledávání: '"KIR Ligand"'
Autor:
Hisashi Ishida, Yuta Kawahara, Daisuke Tomizawa, Yasuhiro Okamoto, Asahito Hama, Yuko Cho, Katsuyoshi Koh, Yuhki Koga, Nao Yoshida, Maho Sato, Kiminori Terui, Naoyuki Miyagawa, Akihiro Watanabe, Junko Takita, Ryoji Kobayashi, Masaki Yamamoto, Kenichiro Watanabe, Keiko Okada, Koji Kato, Kimikazu Matsumoto, Moeko Hino, Ken Tabuchi, Hirotoshi Sakaguchi
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Although killer Ig-like receptor ligands (KIR-L) mismatch has been associated with alloreactive natural killer cell activity and potent graft-versus-leukemia (GVL) effect among adults with acute myeloid leukemia (AML), its role among childre
Externí odkaz:
https://doaj.org/article/4ed23d4696ce46eb92bcc28379e65728
Autor:
Yu Zhang, Chenjing Ye, Haojie Zhu, Youran Zhuang, Shaozhen Chen, Yingxi Weng, Jinhua Ren, Xiaofeng Luo, Jing Zheng, Xiaoyun Zheng, Jing Li, Lingqiong Lan, Yongxin Xie, Zhongchao Han, Jianda Hu, Ting Yang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
ObjectivesKiller cell immunoglobulin like receptor (KIR) can trigger the alloreactivity of NK cells. However, there is no clear consensus as to their function. Here, we investigated the potential influence of KIR mismatch and KIR alleles on the outco
Externí odkaz:
https://doaj.org/article/21e28f128179423ba9020ff7823c1e7b
Autor:
Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Inflammation and Regeneration, Vol 41, Iss 1, Pp 1-9 (2021)
Abstract In the regenerative medicine field, allogenic transplantation of regenerated tissues has been promoted because autologous transplantation setting is costly and time-consuming to prepare and therefore unsuitable for emergent treatment. To avo
Externí odkaz:
https://doaj.org/article/aa99cfccd2a64e699dbab051c562a779
Akademický článek
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Autor:
Hiroshi Ichise, Seiji Nagano, Takuya Maeda, Masaki Miyazaki, Yuki Miyazaki, Hiroto Kojima, Nobuyo Yawata, Makoto Yawata, Hidenori Tanaka, Hiroh Saji, Kyoko Masuda, Hiroshi Kawamoto
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 853-867 (2017)
HLA haplotype-homozygous (HLA-homo) induced pluripotent stem cells (iPSCs) are being prepared to be used for allogeneic transplantation of regenerated tissue into recipients carrying an identical haplotype in one of the alleles (HLA-hetero). However,
Externí odkaz:
https://doaj.org/article/55716d85db5e4dffa93d13d9157f0cc5
Publikováno v:
Revista Espanola de Enfermedades Digestivas, Vol 107, Iss 9, Pp 547-553 (2015)
Backgound and aim: There are some common genetic features between celiac disease (CD) and diabetes mellitus type 1 (DM). However, the genetic risk factors have not been fully clarified for CD and the co-occurrence of CD and DM. KIR (killer immunoglob
Externí odkaz:
https://doaj.org/article/7308c9873f6f4039869294165e48cebf
Autor:
Carmen Martínez-Losada, Carmen Martín, Rafael Gonzalez, Bárbara Manzanares, Estefania García-Torres, Concha Herrera
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Donor natural killer (NK) cells can destroy residual leukemic cells after allogeneic hematopoietic stem cell transplantation. This effect is based on the interaction of killer-cell immunoglobulin-like receptors (KIR) of donor NK cells with ligands of
Externí odkaz:
https://doaj.org/article/d6ef4e19542b46de9fb3cbbab5fe3e5f
Autor:
Amy K. Erbe, Wei Wang, Patrick K. Reville, Lakeesha Carmichael, KyungMann Kim, Eneida A. Mendonca, Yiqiang Song, Jacquelyn A. Hank, Wendy B. London, Arlene Naranjo, Fangxin Hong, Michael D. Hogarty, John M. Maris, Julie R. Park, M. F. Ozkaynak, Jeffrey S. Miller, Andrew L. Gilman, Brad Kahl, Alice L. Yu, Paul M. Sondel
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Killer-cell immunoglobulin-like receptors (KIRs) are a family of glycoproteins expressed primarily on natural killer cells that can regulate their function. Inhibitory KIRs recognize MHC class I molecules (KIR-ligands) as ligands. We have reported as
Externí odkaz:
https://doaj.org/article/d5bf7e8e13a14ddfb5d4f0085470960e
Autor:
Jonathan A. Shortt, Guobin Zhang, Paul Norman, Lisbeth A. Guethlein, Hong-yan Zou, Mingzhong Tang, Genelle F. Harrison, Liumei He, Peter Parham, William H. Palmer, R. Chen, Zhihui Deng, Mary Carrington, Wenxu Hong, Ge Sun, Christopher R. Gignoux, Xiaojiang Gao, Siqi Cai, Jianxin Zhen, Qiong Yu, Neda Nemat-Gorgani
Publikováno v:
Molecular Biology and Evolution
Human natural killer (NK) cells are essential for controlling infection, cancer, and fetal development. NK cell functions are modulated by interactions between polymorphic inhibitory killer cell immunoglobulin-like receptors (KIR) and polymorphic HLA
Publikováno v:
American Journal of Hematology. 95(12):1590-1598
Allogeneic hematopoietic stem cell transplantation (alloSCT) for myeloid leukemia remains one of the most effective anti-tumor treatments available, capable of curing an increasingly higher proportion of patients. Alloreactivity generated by T cells