Zobrazeno 1 - 10
of 39
pro vyhledávání: '"KIHITO TAKAHASHI"'
Autor:
Kihito Takahashi
Publikováno v:
Annals of Oncology. 33:S407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b61712f5ea6e80ceed4740fa2f06df84
https://doi.org/10.1016/j.annonc.2022.05.368
https://doi.org/10.1016/j.annonc.2022.05.368
Autor:
Kihito Takahashi
Publikováno v:
YAKUGAKU ZASSHI. 129:237-240
As Japan becomes more integrated into the global market, pharmaceutical research and development (R&D) in Japan faces considerable challenges. While global simultaneous development including Asian countries has become a common strategy for multi-nati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6988bca451996cb8dd352725f56cfd05
https://doi.org/10.1248/yakushi.129.237
https://doi.org/10.1248/yakushi.129.237
Autor:
Kihito Takahashi
Publikováno v:
International Journal of Pharmaceutical Medicine. 21:331-338
As Japan becomes more integrated into the global market, pharmaceutical research and development (R&D) in the country faces considerable challenges. While global simultaneous drug development including Asian countries has become a common feature for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5388ef7f8d1369279a9e7aefa114411a
https://doi.org/10.2165/00124363-200721050-00003
https://doi.org/10.2165/00124363-200721050-00003
Autor:
Yukio Hirayama, Kenji Nonaka, Toshio Ogihara, Megumi Toki, Kihito Takahashi, Takao Saruta, Hiromichi Suzuki, Hiroaki Matsuoka
Publikováno v:
Hypertension Research. 30:729-739
A randomized, double-blind, placebo-controlled, parallel-group multicenter study was conducted to evaluate the antihypertensive efficacy and safety of 8-week treatment with one of three fixed-dose combinations-losartan 50 mg plus hydrochlorothiazide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81cf0e883099e6eda3072a0315e77e0
https://doi.org/10.1291/hypres.30.729
https://doi.org/10.1291/hypres.30.729
Publikováno v:
Biochemical Journal. 306:331-335
A novel protein [designated protein tyrosine phosphatase-like protein (PTPLP)] which is distantly related to receptor-type protein tyrosine phosphatases (PTPases) was cloned from a rat pheochromocytoma cell line. The PTPLP was detected exclusively in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e93caa6d67e13b22c76c90137897d1
https://doi.org/10.1042/bj3060331
https://doi.org/10.1042/bj3060331
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 26:897-902
Three years have passed since the enforcement of GCP (good clinical practice). Weinvestigated the understanding and reaction of patients and doctors toward informedconsent for clinical trials. The questionnaires were given to outpatients in our clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56dff2ba9d326d8899f7a7a0eb7a9d4d
https://doi.org/10.3999/jscpt.26.897
https://doi.org/10.3999/jscpt.26.897
Autor:
Harry R. Jacobson, Keiko Makita, Jorge H. Capdevila, John R. Falck, Kihito Takahashi, Armando Karara
Publikováno v:
Journal of Clinical Investigation. 94:2414-2420
Excess dietary salt induces a cytochrome P450 arachidonic acid epoxygenase isoform in rat kidneys (Capdevila, J. H., S. Wei, J. Yang, A. Karara, H. R. Jacobson, J. R. Falck, F. P. Guengerich, and R. N. Dubois. 1992. J. Biol. Chem. 267:21720-21726). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bab6574ba80d6f20b9c39038149250
https://doi.org/10.1172/jci117608
https://doi.org/10.1172/jci117608
Publikováno v:
Journal of the American Society of Nephrology. 4:1690-1694
This study was designed to examine the potential effect(s) of dietary supplementation with L-arginine on the renal microcirculation of female Munich-Wistar rats with ablation of 60 to 70% of total renal mass. All rats were fed a standard rat chow con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe77fe3f0f9c2599aad02e081cf2178
https://doi.org/10.1681/asn.v491690
https://doi.org/10.1681/asn.v491690
Publikováno v:
Journal of Clinical Investigation. 91:1507-1515
We assessed the role of leukotrienes (LTs) in Munich-Wistar rats with passive Heymann nephritis (PHN), an animal model of human membranous nephropathy. 10 d after injection of anti-Fx1A antibody, urinary protein excretion rate (Upr) in PHN was signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ae9cfdfc6d8bd6ca3af308828960ed
https://doi.org/10.1172/jci116356
https://doi.org/10.1172/jci116356
Autor:
Keiko Makita, Harry R. Jacobson, Karen A. Munger, Jorge H. Capdevila, Kihito Takahashi, Raymond C. Harris, Armando Karara, Kamal F. Badr
Publikováno v:
Journal of the American Society of Nephrology. 3:1496-1500
After unilateral nephrectomy (UNx) in the rat, cytochrome P-450 (cP-450)-linked arachidonate enzymatic activity was markedly and specifically induced in microsomal fractions from the remaining kidney. The enzymatic activity reached 200% at 1 wk and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8429469cc065628a4da51ec3dac84036
https://doi.org/10.1681/asn.v381496
https://doi.org/10.1681/asn.v381496