Zobrazeno 1 - 10
of 229
pro vyhledávání: '"KH Weisgraber"'
Autor:
TP Bersot, SJ Russell, SR Thatcher, NK Pomernacki, RW Mahley, KH Weisgraber, TL Innerarity, CS Fox
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 7, Pp 1149-1154 (1993)
The prevalence of familial defective apolipoprotein (apo) B-100 (FDB) was determined by sampling 5,160 volunteer subjects from among 14,058 eligible employees of a bank in California. The sample was ethnically diverse (44.6% of the population was non
Externí odkaz:
https://doaj.org/article/69efb2936b7c417da6c76e631d24d678
Publikováno v:
Journal of Lipid Research, Vol 34, Iss 3, Pp 447-453 (1993)
Apolipoprotein (apo) E Leiden is a rare variant of human apoE characterized by defective receptor binding and associated with dominant transmission of type III hyperlipoproteinemia. In heterozygotes, apoE Leiden is present in higher concentrations in
Externí odkaz:
https://doaj.org/article/0054c4cc8356490e930c89d719f2dc99
Publikováno v:
Journal of Lipid Research, Vol 33, Iss 11, Pp 1677-1688 (1992)
Previous studies suggest that during nerve regeneration apoE acts as a lipid transport protein that assists in the rapid initial extension of axons and then in their myelination. To determine whether apoE and/or apoE-containing lipoproteins can modul
Externí odkaz:
https://doaj.org/article/bfbe9289884249738d0a9ca4e17fa40c
Publikováno v:
Journal of Lipid Research, Vol 32, Iss 3, Pp 521-528 (1991)
Apolipoprotein (apo) E polymorphism has a significant effect on plasma cholesterol and low density lipoprotein cholesterol concentrations. The association of two apoE5 isoforms with elevated plasma low density lipoprotein cholesterol levels in two un
Externí odkaz:
https://doaj.org/article/b52536dfc161449397674e19936298c5
Autor:
TL Innerarity, RW Mahley, KH Weisgraber, TP Bersot, RM Krauss, GL Vega, SM Grundy, W Friedl, J Davignon, BJ McCarthy
Publikováno v:
Journal of Lipid Research, Vol 31, Iss 8, Pp 1337-1349 (1990)
Familial defective apolipoprotein B-100 is a genetic disorder of apolipoprotein B-100 that causes moderate to severe hypercholesterolemia. A single amino acid mutation in apolipoprotein B diminishes the ability of low density lipoproteins to bind to
Externí odkaz:
https://doaj.org/article/e84507283cdb4cfaabfc4a320d3b82e2
Publikováno v:
Journal of Lipid Research, Vol 31, Iss 3, Pp 535-543 (1990)
Homozygosity for the apolipoprotein (apo) E variant apoE2(158 Arg—-Cys) invariably gives rise to dysbetalipoproteinemia, and when associated with obesity or a gene for hyperlipidemia, results in type III hyperlipoproteinemia. The association of the
Externí odkaz:
https://doaj.org/article/87235570022e42c2becaa2230800b82f
Autor:
Mohamed ZAIOU, Ks, Arnold, Ym, Newhouse, Tl, Innerarity, Kh, Weisgraber, Ml, Segall, Mc, Phillips, Lund-Katz S
Publikováno v:
Europe PubMed Central
Conserved lysines and arginines within amino acids 140-150 of apolipoprotein (apo) E are crucial for the interaction between apoE and the low density lipoprotein receptor (LDLR). To explore the roles of amphipathic alpha-helix and basic residue organ
Autor:
Adeosun SO; Department of Pathology, University Mississippi Medical Center, Jackson, MS 39216, United States; Program in Neuroscience, University Mississippi Medical Center, Jackson, MS 39216, United States., Hou X; Department of Pathology, University Mississippi Medical Center, Jackson, MS 39216, United States; Program in Neuroscience, University Mississippi Medical Center, Jackson, MS 39216, United States., Shi L; Department of Pathology, University Mississippi Medical Center, Jackson, MS 39216, United States., Stockmeier CA; Program in Neuroscience, University Mississippi Medical Center, Jackson, MS 39216, United States; Department of Psychiatry and Human Behavior, University Mississippi Medical Center, Jackson, MS 39216, United States., Zheng B; Department of Pathology, University Mississippi Medical Center, Jackson, MS 39216, United States., Raffai RL; University of California, San Francisco and VA Medical Center, San Francisco, CA 94121, United States., Weisgraber KH; Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141, United States., Mosley TH; Memory Impairment and Neurodegenerative Dementia Center, University Mississippi Medical Center, Jackson, MS 39216, United States., Wang JM; Department of Pathology, University Mississippi Medical Center, Jackson, MS 39216, United States; Program in Neuroscience, University Mississippi Medical Center, Jackson, MS 39216, United States; Department of Psychiatry and Human Behavior, University Mississippi Medical Center, Jackson, MS 39216, United States; Department of Pharmacology and Toxicology, University Mississippi Medical Center, Jackson, MS 39216, United States; Memory Impairment and Neurodegenerative Dementia Center, University Mississippi Medical Center, Jackson, MS 39216, United States. Electronic address: jwang@umc.edu.
Publikováno v:
Neurobiology of learning and memory [Neurobiol Learn Mem] 2019 May; Vol. 161, pp. 106-114. Date of Electronic Publication: 2019 Apr 04.
Autor:
Peters-Libeu C; Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA., Miller J, Rutenber E, Newhouse Y, Krishnan P, Cheung K, Hatters D, Brooks E, Widjaja K, Tran T, Mitra S, Arrasate M, Mosquera LA, Taylor D, Weisgraber KH, Finkbeiner S
Publikováno v:
Journal of molecular biology [J Mol Biol] 2012 Aug 24; Vol. 421 (4-5), pp. 587-600. Date of Electronic Publication: 2012 Jan 28.
Autor:
Zhang L; Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, California, USA., Yan F, Zhang S, Lei D, Charles MA, Cavigiolio G, Oda M, Krauss RM, Weisgraber KH, Rye KA, Pownall HJ, Qiu X, Ren G
Publikováno v:
Nature chemical biology [Nat Chem Biol] 2012 Feb 19; Vol. 8 (4), pp. 342-9. Date of Electronic Publication: 2012 Feb 19.