Zobrazeno 1 - 10
of 468
pro vyhledávání: '"KG Mann"'
Publikováno v:
Blood. 86:2616-2623
The isolation and characterization of baboon plasma factor V (FV) were performed for the development of an in vivo model for studying factor V/Va physiology in nonhuman primates. Baboon FV was purified by immunoaffinity chromatography with an antihum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3676638139e6e9a960dbb0ca61accf
https://doi.org/10.1182/blood.v86.7.2616.bloodjournal8672616
https://doi.org/10.1182/blood.v86.7.2616.bloodjournal8672616
Publikováno v:
Blood. 86:1820-1827
We have characterized the factor V protein and cDNA of a patient displaying factor V deficiency (parahemophilia) and correlated the reduced activity with a missense mutation of Ala221-to-Val. Plasma from the subject individual (C1) presented reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070da900ef9f06de35c8c405fd0879c5
https://doi.org/10.1182/blood.v86.5.1820.bloodjournal8651820
https://doi.org/10.1182/blood.v86.5.1820.bloodjournal8651820
Publikováno v:
Blood. 84:687-690
Clinical manifestations of arterial and venous thrombosis in a family with protein C deficiency was associated with two mutations in the light chain of protein C: Glu20-->Ala and Val34-->Met. Further studies showed that the mutation Glu20-->Ala which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61e1936b34a245796810120cef66b2c3
https://doi.org/10.1182/blood.v84.3.687.bloodjournal843687
https://doi.org/10.1182/blood.v84.3.687.bloodjournal843687
Publikováno v:
Blood. 76:755-766
This study describes a process by which serine proteases that contain an S-1 arginine subsite and active site histidine may be inactivated and subsequently quantitated using a combination of peptidyl chloromethylketone chemistry and immune recognitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3899b4f7042787fe38808a3b1f2629
https://doi.org/10.1182/blood.v76.4.755.bloodjournal764755
https://doi.org/10.1182/blood.v76.4.755.bloodjournal764755
Autor:
RJ Jr Kelm, KG Mann
Publikováno v:
Blood. 75:1105-1113
Our laboratory has previously shown that osteonectin, an abundant noncollagenous bone protein, is contained in and secreted from human platelets. In this study, the distribution of osteonectin both in the supernatant and on the platelet surface after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27307f08c298415cee3efaccff616dba
https://doi.org/10.1182/blood.v75.5.1105.bloodjournal7551105
https://doi.org/10.1182/blood.v75.5.1105.bloodjournal7551105
Publikováno v:
Blood. 76(11)
A 68-year-old man, following mitral valve replacement, presented with a low-grade chronic consumptive coagulopathy. Laboratory analysis showed mild fibrinolysis, minimal effect of coumadin therapy, and a prolonged thrombin time (greater than 150 seco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e674b2a6908c3191e7f5c36169072ed9
https://pubmed.ncbi.nlm.nih.gov/2257299
https://pubmed.ncbi.nlm.nih.gov/2257299
Publikováno v:
Blood. 76(1)
During the past 20 years contributions from many laboratories have led to the development of isolation procedures, delineation of primary structures, and more recently, to the expression of recombinant proteins associated with the coagulation cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f591730014014eaf19d53ce79dd7a9c4
https://pubmed.ncbi.nlm.nih.gov/2194585
https://pubmed.ncbi.nlm.nih.gov/2194585
Autor:
KG Mann, GA FitzGerald
Publikováno v:
The American Journal of Clinical Nutrition. 56:815S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6039f54f8482c9cdfaa43042f651065
https://doi.org/10.1093/ajcn/56.4.815s
https://doi.org/10.1093/ajcn/56.4.815s
Publikováno v:
Blood. 65:1396-1406
Specific monoclonal and polyclonal antibody reagents and a double antigen indirect immunofluorescence microscopy technique were used to visualize coagulation factor V in human bone marrow. Marrow aspirates were smeared directly on glass slides, or wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25952e6a68614c622e19db7b8181cd39
https://doi.org/10.1182/blood.v65.6.1396.bloodjournal6561396
https://doi.org/10.1182/blood.v65.6.1396.bloodjournal6561396
Publikováno v:
Blood. 47:833-840
Incubation of human platelets in plasma containing a suspension of latex particles for 1–90 min resulted in progressive accumulation of particles in the open-channel system, followed by localization of latex in electron-opaque vacuoles. After 60 mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed5ffbb22fd84ad826000e91e74cc655
https://doi.org/10.1182/blood.v47.5.833.bloodjournal475833
https://doi.org/10.1182/blood.v47.5.833.bloodjournal475833