Zobrazeno 1 - 10
of 77
pro vyhledávání: '"KEWEN HE"'
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafiq, Thomas S. Riad, Yun Hu, Ailing Huang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background Combining interleukin-2 (IL-2) with radiotherapy (RT) and immune checkpoint blockade (ICB) has emerged as a promising approach to address ICB resistance. However, conventional IL-2 cytokine therapy faces constraints owing to its b
Externí odkaz:
https://doaj.org/article/d5dfdad3aeaf4ef7a03ae6638ec04617
Autor:
Jun Li, Xin Deng, Zhongyuan Lu, Xiaoying Li, Li Hou, Jun Jiang, Fengyuan Yang, Junjin Zhang, Kewen He
Publikováno v:
Case Studies in Construction Materials, Vol 21, Iss , Pp e03575- (2024)
Using recycled concrete fines (RFs) as a supplementary cementitious material in blended cement systems offers potential benefits for the construction industry. This study investigated the mechanical properties, hydration development, and microstructu
Externí odkaz:
https://doaj.org/article/f449b2663ebe4530b032fd4e202cdc9a
Autor:
Nahum Puebla-Osorio, Natalie Wall Fowlkes, Hampartsoum B. Barsoumian, Kristina Xega, Gitika Srivastava, Claudia Kettlun-Leyton, Sara Nizzero, Tiffany Voss, Thomas S. Riad, Christina Wong, Ailing Huang, Yun Hu, Joylise Mitchell, Mingee Kim, Zahid Rafiq, Kewen He, Duygu Sezen, Ethan Hsu, Fatemeh Masrorpour, Aurian Maleki, Carola Leuschner, Maria Angelica Cortez, Philipp Oertle, Marko Loparic, Marija Plodinec, Janet L. Markman, James W. Welsh
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionEffective infiltration of chimeric antigen receptor T (CAR-T) cells into solid tumors is critical for achieving a robust antitumor response and improving therapeutic outcomes. While CAR-T cell therapies have succeeded in hematologic malig
Externí odkaz:
https://doaj.org/article/e15d8e28463245d5a2e2e3d70c939f5b
Autor:
Li Li, Kewen He, Tao Zhou, Yang Xu, Jiaohui Pang, Qingxi Yu, Yongsheng Gao, Hongjin Shi, He Zhu, Mengke Li, Jinming Yu, Shuanghu Yuan
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1649-1664 (2024)
Stage pIIIA/N2 non‐small cell lung cancer (NSCLC) is primarily treated by complete surgical resection combined with neoadjuvant/adjuvant therapies. However, up to 40% of patients experience tumor recurrence. Here, we studied 119 stage pIIIA/N2 NSCL
Externí odkaz:
https://doaj.org/article/e5aa2ebe6820457a9b5c97ae20b2adfd
Autor:
Yun Hu, Alexey Revenko, Hampartsoum Barsoumian, Genevieve Bertolet, Natalie Wall Fowlkes, Hadi Maazi, Morgan Maureen Green, Kewen He, Duygu Sezen, Tiffany A. Voss, Claudia S Kettlun Leyton, Fatemeh Masrorpour, Zahid Rafiq, Nahum Puebla-Osorio, Carola Leuschner, Robert MacLeod, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The combination of radiotherapy and immunotherapy (immunoradiotherapy) has been increasingly used for treating a wide range of cancers. However, some tumors are resistant to immunoradiotherapy. We have previously shown that MER pr
Externí odkaz:
https://doaj.org/article/bfe32f32799d4d64804e7e64eb090fe4
Autor:
Kewen He, Nahum Puebla-Osorio, Hampartsoum B. Barsoumian, Duygu Sezen, Zahid Rafq, Thomas S. Riad, Yun Hu, Ailing Huang, Tifany A. Voss, Claudia S. Kettlun Leyton, Lily Jae Schuda, Ethan Hsu, Joshua Heiber, Maria-Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6dc555a438aa4754a8956da5b8b452ea
Autor:
Yun Hu, Sébastien Paris, Genevieve Bertolet, Hampartsoum B. Barsoumian, Kewen He, Duygu Sezen, Dawei Chen, Mark Wasley, Jordan DA SILVA, Joylise A. Mitchell, Tiffany A. Voss, Fatemeh Masrorpour, Claudia Kettlun Leyton, Liangpeng Yang, Carola Leuschner, Nahum Puebla-Osorio, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background While improvements in immunoradiotherapy have significantly improved outcomes for cancer patients, this treatment approach has nevertheless proven ineffective at controlling the majority of malignancies. One of the mechanisms of r
Externí odkaz:
https://doaj.org/article/a090d791bef0465c93bf5eb25e2451f7
Autor:
Kewen He, Li Li, Aijie Li, Yang Xu, Jiaohui Pang, Dianbin Mu, Jie Ma, Hong Ge, Aurian Maleki, Xueting Qin, Xian Zhang, Qiuxiang Ou, Yang Shao, Jinming Yu, Shuanghu Yuan
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 6, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/b4cd1baf44a144adaa460a0115b6de2c
Autor:
Yun Hu, Sébastien Paris, Hampartsoum Barsoumian, Chike O. Abana, Kewen He, Duygu Sezen, Mark Wasley, Fatemeh Masrorpour, Dawei Chen, Liangpeng Yang, Joe D. Dunn, Saumil Gandhi, Quynh-Nhu Nguyen, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Combining radiotherapy with PD1 blockade has had impressive antitumor effects in preclinical models of metastatic lung cancer, although anti-PD1 resistance remains problematic. Here, we report results from a triple-combination the
Externí odkaz:
https://doaj.org/article/07dc075fcbd049008b2e635b70dfaf0b
Autor:
Duygu Sezen, Hampartsoum B. Barsoumian, Kewen He, Yun Hu, Qi Wang, Chike O. Abana, Nahum Puebla-Osorio, Ethan Y. Hsu, Mark Wasley, Fatemeh Masrorpour, Jing Wang, Maria Angelica Cortez, James W. Welsh
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Radiation therapy (XRT) has a well-established role in cancer treatment. Given the encouraging results on immunostimulatory effects, radiation has been increasingly used with immune-check-point inhibitors in metastatic disease, especially when immuno
Externí odkaz:
https://doaj.org/article/20ba2088e44043fcbe418952fcb64974