Enhancing discovery of genetic variants for posttraumatic stress disorder through integration of quantitative phenotypes and trauma exposure information

Autor: Maihofer, Adam X., Choi, Karmel W., Coleman, Jonathan R.I., Daskalakis, Nikolaos P., Denckla, Christy A., Ketema, Elizabeth, Morey, Rajendra A., Polimanti, Renato, Ratanatharathorn, Andrew, Torres, Katy, Wingo, Aliza P., Zai, Clement C., Aiello, Allison E., Almli, Lynn M., Amstadter, Ananda B., Andersen, Soren B., Andreassen, Ole A., Arbisi, Paul A., Ashley-Koch, Allison E., Austin, S. Bryn, Avdibegović, Esmina, Borglum, Anders D., Babić, Dragan, Bækvad-Hansen, Marie, Baker, Dewleen G., Beckham, Jean C., Bierut, Laura J., Bisson, Jonathan I., Boks, Marco P., Bolger, Elizabeth A., Bradley, Bekh, Brashear, Meghan, Breen, Gerome, Bryant, Richard A., Bustamante, Angela C., Bybjerg-Grauholm, Jonas, Calabrese, Joseph R., Caldas-de-Almeida, José M., Chen, Chia Yen, Dale, Anders M., Dalvie, Shareefa, Deckert, Jürgen, Delahanty, Douglas L., Dennis, Michelle F., Disner, Seth G., Domschke, Katharina, Duncan, Laramie E., Džubur Kulenović, Alma, Erbes, Christopher R., Evans, Alexandra, Farrer, Lindsay A., Feeny, Norah C., Flory, Janine D., Forbes, David, Franz, Carol E., Galea, Sandro, Garrett, Melanie E., Gautam, Aarti, Gelaye, Bizu, Gelernter, Joel, Geuze, Elbert, Gillespie, Charles F., Goçi, Aferdita, Gordon, Scott D., Guffanti, Guia, Hammamieh, Rasha, Hauser, Michael A., Heath, Andrew C., Hemmings, Sian M.J., Hougaard, David Michael, Jakovljević, Miro, Jett, Marti, Johnson, Eric Otto, Jones, Ian, Jovanovic, Tanja, Qin, Xue Jun, Karstoft, Karen Inge, Kaufman, Milissa L., Kessler, Ronald C., Khan, Alaptagin, Kimbrel, Nathan A., King, Anthony P., Koen, Nastassja, Kranzler, Henry R., Kremen, William S., Lawford, Bruce R., Lebois, Lauren A.M., Lewis, Catrin, Liberzon, Israel, Linnstaedt, Sarah D., Logue, Mark W., Lori, Adriana, Lugonja, Božo, Luykx, Jurjen J., Lyons, Michael J., Maples-Keller, Jessica L., Marmar, Charles, Martin, Nicholas G., Maurer, Douglas, Mavissakalian, Matig R.

Publikováno v: Universidad Peruana de Ciencias Aplicadas (UPC)Repositorio Academico - UPCBiological Psychiatry.

Background: Posttraumatic stress disorder (PTSD) is heritable and a potential consequence of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD phenotype measurement and incorporation of lifetime trauma exposure (LTE

Externí odkaz: http://hdl.handle.net/10757/659489

Reliability and procedural validity of University of Michigan-CIDI DSM-III-R phobic disorders

Autor: Wittchen, Hans-Ulrich, Zhao, Shanyang, Abelson, Jamie M., Abelson, James L., Kessler, Ronald C.

Publikováno v: Psychological Medicine. 26(6):1169-1177

We evaluate the long-term test–retest reliability and procedural validity of phobia diagnoses in the UM-CIDI, the version of the Composite International Diagnostic Interview, used in the US National Co-morbidity Survey (NCS) and a number of other o

Externí odkaz: https://tud.qucosa.de/id/qucosa%3A26399
https://tud.qucosa.de/api/qucosa%3A26399/attachment/ATT-0/

A prediction model for differential resilience to the effects of combat‐related stressors in US army soldiers.

Autor: Kessler, Ronald C.¹ (AUTHOR) kessler@hcp.med.harvard.edu, Bossarte, Robert M.^2,3 (AUTHOR), Hwang, Irving¹ (AUTHOR), Luedtke, Alex^4,5 (AUTHOR), Naifeh, James A.⁶ (AUTHOR), Nock, Matthew K.⁷ (AUTHOR), Petukhova, Maria¹ (AUTHOR), Sadikova, Ekaterina^1,8 (AUTHOR), Sampson, Nancy A.¹ (AUTHOR), Sverdrup, Erik⁹ (AUTHOR), Zubizarreta, Jose R.¹ (AUTHOR), Wager, Stefan¹⁰ (AUTHOR), Wagner, James¹¹ (AUTHOR), Stein, Murray B.¹² (AUTHOR), Ursano, Robert J.⁶ (AUTHOR)

Publikováno v: International Journal of Methods in Psychiatric Research. Dec2024, Vol. 33 Issue 4, p1-14. 14p.

Can the potential benefit of individualizing treatment be assessed using trial summary statistics alone?

Autor: Galanter, Nina, Carone, Marco, Kessler, Ronald C., Luedtke, Alex

Individualizing treatment assignment can improve outcomes for diseases with patient-to-patient variability in comparative treatment effects. When a clinical trial demonstrates that some patients improve on treatment while others do not, it is temptin

Externí odkaz: http://arxiv.org/abs/2211.00163

Broadening the definition of generalized anxiety disorder: Effects on prevalence and associations with other disorders in the National Comorbidity Survey Replication

Autor: Ruscio, Ayelet Meron, Chiu, Wai Tat, Roy-Byrne, Peter, Stang, Paul E., Stein, Dan J., Wittchen, Hans-Ulrich, Kessler, Ronald C.

Publikováno v: Journal of Anxiety Disorders, Bd. 21 (2007), Nr. 5, S. 662–676, ISSN: 0887-6185

Concerns have been raised that the DSM-IV requirements of 6-month duration, excessive worry, and three associated symptoms exclude a substantial number of people with clinically significant anxiety from a diagnosis of generalized anxiety disorder (GA

Externí odkaz: https://tud.qucosa.de/id/qucosa%3A26832
https://tud.qucosa.de/api/qucosa%3A26832/attachment/ATT-0/