Zobrazeno 1 - 10
of 17
pro vyhledávání: '"KENNETH STAPLETON"'
Autor:
Vishnu Amaram Samara, Sadhan Das, Marpadga A. Reddy, Vinay Singh Tanwar, Kenneth Stapleton, Amy Leung, Maryam Abdollahi, Rituparna Ganguly, Linda Lanting, Rama Natarajan
Publikováno v:
Cells, Vol 10, Iss 10, p 2696 (2021)
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown. We describe a novel AngII-induced lncRNA Alivec (Angiotensin II-induce
Externí odkaz:
https://doaj.org/article/bf30d0f40d4f4e429a491aaf3b6ff8e0
Autor:
Amanda Ackley, Alexandra Lenox, Kenneth Stapleton, Stuart Knowling, Tim Lu, Kenny S Sabir, Peter K Vogt, Kevin V Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Small noncoding antisense RNAs (sasRNAs) guide epigenetic silencing complexes to target loci in human cells and modulate gene transcription. When these targeted loci are situated within a promoter, long-term, stable epigenetic silencing of transcript
Externí odkaz:
https://doaj.org/article/20c51ae8a73c411c98bf011a2eeb55d1
Autor:
Stuart Knowling, Kenneth Stapleton, Anne-Marie W Turner, Eugen Uhlmann, Thomas Lehmann, Jörg Vollmer, Kevin V Morris
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Small noncoding RNAs (ncRNAs) have been shown to guide epigenetic silencing complexes to target loci in human cells. When targeted to gene promoters, these small RNAs can lead to long-term stable epigenetic silencing of gene transcription. To date, s
Externí odkaz:
https://doaj.org/article/5b574ba039c64920ad6206fbd35c5806
Autor:
Vinay Singh Tanwar, Marpadga A. Reddy, Sadhan Das, Vishnu Amaram Samara, Maryam Abdollahi, Suchismita Dey, Vajir Malek, Rituparna Ganguly, Kenneth Stapleton, Linda Lanting, Patrick Pirrotte, Rama Natarajan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology.
Background: Obesity and diabetes are associated with elevated free fatty acids like palmitic acid (PA), which promote chronic inflammation and impaired inflammation resolution associated with cardiometabolic disorders. Long noncoding RNAs (lncRNAs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b55a55e54878fd9a453bf14c2d9e1da6
https://doi.org/10.1161/atvbaha.122.318536
https://doi.org/10.1161/atvbaha.122.318536
Autor:
VINAY S. TANWAR, MARPADGA A. REDDY, SADHAN DAS, VISHNU AMARAM SAMARA, MARYAM ABDOLLAHI, SUCHISMITA DEY, RITUPARNA GANGULY, LINDA L. LANTING, KENNETH STAPLETON, RAMA NATARAJAN
Publikováno v:
Diabetes. 71
Obesity and diabetes are associated with chronic inflammation induced by the elevated circulating levels of Palmitic acid (PA) and also result from impaired resolution of inflammation in macrophages. Here, we examined the role of PA-induced long non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f37b6f6560a56dce47d62a1431000640
https://doi.org/10.2337/db22-451-p
https://doi.org/10.2337/db22-451-p
Autor:
Rengasamy Palanivel, Rama Natarajan, Lingxiao Zhang, Vishnu Amaram, Jeffrey A. Deiuliis, Kenneth Stapleton, Zhuo Chen, Linda Lanting, Marpadga A. Reddy, Sadhan Das, Amy Leung
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 40:914-928
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular complications. This inflammatory state is caused by release of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d316219af70957369e6209b411253e8d
https://doi.org/10.1161/atvbaha.119.313359
https://doi.org/10.1161/atvbaha.119.313359
Autor:
Kenneth, Stapleton, Sadhan, Das, Marpadga A, Reddy, Amy, Leung, Vishnu, Amaram, Linda, Lanting, Zhuo, Chen, Lingxiao, Zhang, Rengasamy, Palanivel, Jeffrey A, Deiuliis, Rama, Natarajan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular compl
Objective: Systemic low-grade inflammation associated with obesity and metabolic syndrome is a strong risk factor for the development of diabetes mellitus and associated cardiovascular compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1031fb37f40b47b3ed7706340bd4a36
https://pubmed.ncbi.nlm.nih.gov/32078363
https://pubmed.ncbi.nlm.nih.gov/32078363
Autor:
Vinay Singh Tanwar, Kenneth Stapleton, Linda Lanting, Rituparna Ganguly, Rama Natarajan, Vishnu Amaram, Marpadga A. Reddy, Sadhan Das
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c31307c56721a08d26e4aeecfff044f8
https://doi.org/10.1096/fasebj.2020.34.s1.06582
https://doi.org/10.1096/fasebj.2020.34.s1.06582
Autor:
Sadhan Das, Dustin E. Schones, Sridevi Devaraj, Marpadga A. Reddy, Parijat Senapati, Kenneth Stapleton, Mei Wang, Vishnu Amaram, Linda Lanting, Rama Natarajan, Rituparna Ganguly, Lingxiao Zhang
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 38(8)
Objective— Macrophages play key roles in inflammation and diabetic vascular complications. Emerging evidence implicates long noncoding RNAs in inflammation, but their role in macrophage dysfunction associated with inflammatory diabetic complication
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54914eedb2bcdb813b52d53c224daf2d
https://pubmed.ncbi.nlm.nih.gov/31017820
https://pubmed.ncbi.nlm.nih.gov/31017820
Autor:
Wei Wang, Mei Wang, Marpadga A. Reddy, Kenneth Stapleton, Zhuo Chen, Xinyue Zhang, Parijat Senapati, Qinghao Zhao, Linda Lanting, Bin Zhang, Mitsuo Kato, Haitong Zhang, Yongjian Wu, Qianyun Guo, Hyung Jung Oh, Vishnu Amaram, Rama Natarajan, Sadhan Das, Amy Leung, Erli Zhang
Publikováno v:
The FASEB Journal. 32
Rationale: AngII (angiotensin II)-mediated vascular smooth muscle cell (VSMC) dysfunction plays a major role in hypertension. Long noncoding RNAs have elicited much interest, but their molecular roles in AngII actions and hypertension are unclear. Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ee14b2440b817149be9c4273cb1901
https://doi.org/10.1096/fasebj.2018.32.1_supplement.525.6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.525.6