Zobrazeno 1 - 10
of 74
pro vyhledávání: '"KENJIRO BANDOW"'
Autor:
Tomoyuki Abe, Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-ichi Tanuma, Hiroshi Takeshima
Publikováno v:
Medicines, Vol 10, Iss 7, p 43 (2023)
Background. Many anti-cancer drugs used in clinical practice cause adverse events such as oral mucositis, neurotoxicity, and extravascular leakage. We have reported that two 3-styrylchromone derivatives, 7-methoxy-3-[(1E)-2-phenylethenyl]-4H-1-benzop
Externí odkaz:
https://doaj.org/article/31dc0e9c3dec488e805ec9ceba69031b
Autor:
Li-Min Zhu, Hai-Xia Shi, Masahiro Sugimoto, Kenjiro Bandow, Hiroshi Sakagami, Shigeru Amano, Hai-Bin Deng, Qing-Yu Ye, Yun Gai, Xiao-Li Xin, Zhen-Ye Xu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Feiyanning formula (FYN) is a traditional Chinese medicine (TCM) prescription used for more than 20 years in the treatment of lung cancer. FYN is composed of Astragalus membranaceus, Polygonatum sibiricum, Atractylodes macrocephala, Cornus officinali
Externí odkaz:
https://doaj.org/article/95dab34c439544b0b8c04a9bf7271c98
Autor:
Mohammad Hossain, Praveen K. Roayapalley, Hiroshi Sakagami, Keitaro Satoh, Kenjiro Bandow, Umashankar Das, Jonathan R. Dimmock
Publikováno v:
Medicines, Vol 9, Iss 6, p 35 (2022)
A series of 3,5-bis(benzylidene)-1-dichloroacetyl-4-piperidones 1a–l was evaluated against Ca9-22, HSC-2, HSC-3, and HSC-4 squamous cell carcinomas. Virtually all of the compounds displayed potent cytotoxicity, with 83% of the CC50 values being sub
Externí odkaz:
https://doaj.org/article/e1392a226b3e438e9c17385d828908b1
Autor:
Praveen K. Roayapalley, Hiroshi Sakagami, Keitaro Satoh, Shigeru Amano, Kenjiro Bandow, Renato J. Aguilera, Karla G. Cano Hernandez, Austre Y. Schiaffino Bustamante, Stephen G. Dimmock, Rajendra K. Sharma, Umashankar Das, Jonathan R. Dimmock
Publikováno v:
Medicines, Vol 8, Iss 12, p 78 (2021)
A series of 3,5-bis(benzylidene)-4-piperidones 2a–u were prepared as candidate cytotoxic agents. In general, the compounds are highly toxic to human gingival carcinoma (Ca9-22), human squamous carcinoma-2 (HSC-2) and human squamous carcinoma-4 (HSC
Externí odkaz:
https://doaj.org/article/198a39eb92f24173b32bdf749d37a50d
Publikováno v:
Medicines, Vol 8, Iss 8, p 41 (2021)
Blood calcium homeostasis is critical for biological function. Caldecrin, or chymotrypsin-like elastase, was originally identified in the pancreas as a serum calcium-decreasing factor. The serum calcium-decreasing activity of caldecrin requires the t
Externí odkaz:
https://doaj.org/article/2934ef00e44a4aca8d24f33803bff9d4
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 10, Pp 1806-1820 (2016)
Chemokines are a family of cytokines inducing cell migration and inflammation. Recent reports have implicated the roles of chemokines in cell differentiation. However, little is known about the functional roles of chemokines in adipocytes. Here, we e
Externí odkaz:
https://doaj.org/article/027a815ae34e44b2926b70fda2b546d7
Autor:
Hiroshi Sakagami, Haixia Shi, Kenjiro Bandow, Mineko Tomomura, Akito Tomomura, Misaki Horiuchi, Tomohiro Fujisawa, Takaaki Oizumi
Publikováno v:
Molecules, Vol 23, Iss 8, p 1840 (2018)
Previous studies of the neuroprotective activity of polyphenols have used ununiform culture systems, making it difficult to compare their neuroprotective potency. We have established a new and simple method for preparing differentiated PC12 cells by
Externí odkaz:
https://doaj.org/article/c1c4890f3fe84127a7a62fb75e649bfd
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87229 (2014)
N-acetyl-L-cysteine is known to act as a reactive oxygen species scavenger and used in clinical applications. Previous reports have shown that high-dose N-acetyl-L-cysteine treatment inhibits the expression of proinflammatory cytokines in activated m
Externí odkaz:
https://doaj.org/article/07bb4e8b89a94862acc454c4ab5e325a
Autor:
Kotone Naitoh, Yuta Orihara, Hiroshi Sakagami, Takumi Miura, Keitaro Satoh, Shigeru Amano, Kenjiro Bandow, Yosuke Iijima, Kota Kurosaki, Yoshihiro Uesawa, Masashi Hashimoto, Hidetsugu Wakabayashi
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 5; Pages: 2601
Background: Very few papers covering the anticancer activity of azulenes have been reported, as compared with those of antibacterial and anti-inflammatory activity. This led us to investigate the antitumor potential of fifteen 4,6,8-trimethyl azulene
Publikováno v:
Biochemical and biophysical research communications. 635
TREM2 (Triggering receptor expressed on myeloid cells 2) is the causative gene for Nasu-Hakola disease, which is characterized by multiple bone cysts and leukoencephalopathy. In addition, mutations in this gene have been found to be correlated with t