Zobrazeno 1 - 10
of 96
pro vyhledávání: '"KEN-ICHIRO KOSAI"'
Autor:
Shinsuke Suzuki, Hiroki Kofune, Kimiharu Uozumi, Makoto Yoshimitsu, Naomichi Arima, Kenji Ishitsuka, Shin-ichi Ueno, Ken-ichiro Kosai
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Adult T-cell leukemia/lymphoma (ATL) is a peripheral T-cell malignancy caused by long-term human T-cell leukemia virus type I (HTLV-1) infection. Survivin-responsive, conditionally replicating adenoviruses regulated by multiple tu
Externí odkaz:
https://doaj.org/article/c47502f82558402ab5b7e56c42d82c67
Publikováno v:
Viruses, Vol 13, Iss 12, p 2502 (2021)
Gene therapy is currently in the public spotlight. Several gene therapy products, including oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 vaccines have recently been commercialized. Recombinant adenoviru
Externí odkaz:
https://doaj.org/article/6340549d304945fb954e9d0b40b37f14
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 51-58 (2017)
Human pluripotent stem cells (hPSCs) are a promising source of regenerative material for clinical applications. However, hPSC transplant therapies pose the risk of teratoma formation and malignant transformation of undifferentiated remnants. These pr
Externí odkaz:
https://doaj.org/article/f9dd65cb92f846ed9819b2dd77b341f2
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Incomplete abolition of tumorigenicity creates potential safety concerns in clinical trials of regenerative medicine based on human pluripotent stem cells (hPSCs). Here, we demonstrate that conditionally replicating adenoviruses that specifically tar
Externí odkaz:
https://doaj.org/article/10e0b06c99a74701bf2b53974620e3ae
Autor:
Yasunori Okabe, Tomoyuki Takahashi, Chiaki Mitsumasu, Ken-ichiro Kosai, Eiichiro Tanaka, Toyojiro Matsuishi
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35354 (2012)
Rett syndrome (RTT) is a neurodevelopmetal disorder associated with mutations in the methyl-CpG-binding protein 2 (MeCP2) gene. MeCP2-deficient mice recapitulate the neurological degeneration observed in RTT patients. Recent studies indicated a role
Externí odkaz:
https://doaj.org/article/eacd40d8bb4c4b9788e7186136b65aff
Autor:
Hiroyuki Kuge, Kazuo Ohashi, Takashi Yokoyama, Hiromichi Kanehiro, Michiyoshi Hisanaga, Fumikazu Koyama, Ginny L. Bumgardner, Ken-Ichiro Kosai, Yoshiyuki Nakajima
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Cell-based therapies, including liver tissue engineering following hepatocyte transplantation, have therapeutic potential for several types of liver diseases. Modifications in the methodology to manipulate the donor hepatocytes in a more simple and t
Externí odkaz:
https://doaj.org/article/62c10d750a794a20a37e411222da4494
Publikováno v:
Biochemical and biophysical research communications. 541
Human pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem cells, have the potential to differentiate into a wide variety of cells in vitro and have applications in basic developmental biology research and regenerative me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf315fba3c3d59efd751401e9be4ef
https://pubmed.ncbi.nlm.nih.gov/33482579
https://pubmed.ncbi.nlm.nih.gov/33482579
Publikováno v:
Life sciences. 268
Aims Hepatocyte growth factor (HGF) is a multifunctional cytokine that plays important roles in pancreatic physiology. Approvals of gene therapy drugs have highlighted gene therapy as an innovative new drug modality, but the very recent reports of de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e905b3d38ab48295ce4ddabae5b09e7
https://pubmed.ncbi.nlm.nih.gov/33412216
https://pubmed.ncbi.nlm.nih.gov/33412216
Autor:
Ken-ichiro Kosai
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:1-SL05
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a2e1daa24faf891507b70016c26211
https://doi.org/10.1254/jpssuppl.95.0_1-sl05
https://doi.org/10.1254/jpssuppl.95.0_1-sl05
Autor:
Takashi Kinoshita, Munetsugu Hara, Yuki Nakamura, Toyojiro Matsuishi, Tomoyuki Takahashi, Yushiro Yamashita, Satoko Okayama, Takayuki Taniwaki, Masaki Okamoto, Kei-ichiro Nakamura, Ken-ichiro Kosai, Hiroshi Kida
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in the gene encoding the transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2), located on the X chromosome. Many RTT patients have breathing abnormalities, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8c5b9d4983ad8b2f075f2b37c80b8a
http://link.springer.com/article/10.1038/s41598-017-12293-8
http://link.springer.com/article/10.1038/s41598-017-12293-8