Zobrazeno 1 - 10
of 443
pro vyhledávání: '"KEN TAKEDA"'
Autor:
Koji Uotani, Hiroshi Tazawa, Joe Hasei, Tomohiro Fujiwara, Aki Yoshida, Yasuaki Yamakawa, Toshinori Omori, Kazuhisa Sugiu, Tadashi Komatsubara, Hiroya Kondo, Takuya Morita, Masahiro Kiyono, Suguru Yokoo, Toshiaki Hata, Toshiyuki Kunisada, Ken Takeda, Yasuo Urata, Toshiyoshi Fujiwara, Toshifumi Ozaki
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298292 (2024)
Bone and soft-tissue sarcomas are rare malignancies with histological diversity and tumor heterogeneity, leading to the lack of a common molecular target. Telomerase is a key enzyme for keeping the telomere length and human telomerase reverse transcr
Externí odkaz:
https://doaj.org/article/58fc91a9ec63459b8c0966eb8e2ea242
Autor:
Shohei Tanaka, Noriyuki Kadoya, Yuto Sugai, Mariko Umeda, Miyu Ishizawa, Yoshiyuki Katsuta, Kengo Ito, Ken Takeda, Keiichi Jingu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Early regression—the regression in tumor volume during the initial phase of radiotherapy (approximately 2 weeks after treatment initiation)—is a common occurrence during radiotherapy. This rapid radiation-induced tumor regression may alt
Externí odkaz:
https://doaj.org/article/3249c9ff1d1c44e3a008bbcacdfbc949
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10029- (2022)
Several studies have demonstrated the possibility of positive effects of exposure to music during pregnancy on mental function in humans and animals. Although there remains a core belief in the positive effects of music during pregnancy, the underlyi
Externí odkaz:
https://doaj.org/article/e53b2e9f69cf4758bc5dc89d3e22f945
Autor:
Yuto Sugai, Noriyuki Kadoya, Shohei Tanaka, Shunpei Tanabe, Mariko Umeda, Takaya Yamamoto, Kazuya Takeda, Suguru Dobashi, Haruna Ohashi, Ken Takeda, Keiichi Jingu
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background Radiomics is a new technology to noninvasively predict survival prognosis with quantitative features extracted from medical images. Most radiomics-based prognostic studies of non-small-cell lung cancer (NSCLC) patients have used m
Externí odkaz:
https://doaj.org/article/719d2c43a6d846a7aa73a4d5e987e682
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Background: To protect developing brain from any unfavorable effects, it is necessary to construct experimental techniques that can sensitively detect and evaluate developmental toxicity. We have previously shown that brain perivascular tissues, espe
Externí odkaz:
https://doaj.org/article/8e2eccd8f2094fddbaaa947bdaab4ec1
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
Background and Objectives: Titanium dioxide nanoparticles (TiO2-NP) are important materials used in commercial practice. Reportedly, TiO2-NP exposure during pregnancy can affect the development of the central nervous system in mouse offspring; howeve
Externí odkaz:
https://doaj.org/article/110d0f7709e344d29d121f08de6e7087
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
Air pollution is associated with significant adverse health effects. Recent studies support the idea that inhalation of fine particles can instigate extrapulmonary effects on the cardiovascular system through several pathways. The systemic transfer o
Externí odkaz:
https://doaj.org/article/44f61105e0e14d589025a6c2088188f0
Autor:
Atsuto Onoda, Saki Okamoto, Ryuhei Shimizu, Yasser S. El-Sayed, Shiho Watanabe, Shuhei Ogawa, Ryo Abe, Masao Kamimura, Kohei Soga, Ken Tachibana, Ken Takeda, Masakazu Umezawa
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
Introduction: Particulate air pollution, containing nanoparticles, enhances the risk of pediatric allergic diseases that is potentially associated with disruption of neonatal immune system. Previous studies have revealed that maternal exposure to car
Externí odkaz:
https://doaj.org/article/e71042dd49434d79acb849ba691242b4
Publikováno v:
Frontiers in Toxicology, Vol 3 (2021)
In recent years, an apparent decline in human sperm quality has been observed worldwide. One in every 5.5 couples suffers from infertility, with male reproductive problems contributing to nearly 40% of all infertility cases. Although the reasons for
Externí odkaz:
https://doaj.org/article/3b7aba365213476ab8f7f9a31b746dde
Autor:
Ying-Ji Li, Takako Shimizu, Yusuke Shinkai, Tomomi Ihara, Masao Sugamata, Katsuhito Kato, Maiko Kobayashi, Yukiyo Hirata, Hirofumi Inagaki, Makoto Uzuki, Toshio Akimoto, Masakazu Umezawa, Ken Takeda, Arata Azuma, Masayuki Yamamoto, Tomoyuki Kawada
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 443 (2020)
In the present study, we investigated the role of Nrf2 in airway immune responses induced by diesel exhaust (DE) inhalation in mice. C57BL/6J Nrf2+/+ and Nrf2−/− mice were exposed to DE or clean air for 8 h/day and 6 days/week for 4 weeks. After
Externí odkaz:
https://doaj.org/article/682c858f519a442ea950725793e6f5d3