Zobrazeno 1 - 10
of 75
pro vyhledávání: '"KEMAL YELEKÇİ"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35020- (2024)
Histone deacetylase 6 (HDAC6, Class IIb) is a promising target for anticancer drugs. So far, few nonselective HDAC inhibitors have received regulatory approval as anticancer agents. However, they are associated with cell toxicity. Thus, isoform-selec
Externí odkaz:
https://doaj.org/article/8e8346387d1f4bd9b37223dccb428c0b
Autor:
Göknil Pelin Coşkun, Teodora Djikic, Taha Bartu Hayal, Nezaket Türkel, Kemal Yelekçi, Fikrettin Şahin, Ş. Güniz Küçükgüzel
Publikováno v:
Molecules, Vol 23, Iss 8, p 1969 (2018)
Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In some cancer types the level
Externí odkaz:
https://doaj.org/article/b1e7e91058294a1dbb0abd7b05742faa
Autor:
Elmezayen, Ammar D., Kemal, Yelekçi *
Publikováno v:
In Computational Biology and Chemistry June 2021 92
Autor:
İlkay Küçükgüzel, İlker Demirbolat, Necla Kulabaş, Merve Gürboğa, Özlem Bingöl Özakpınar, Gamze Çiftçi, Kemal Yelekçi, Jianyang Liu, Per-Johan Jakobsson, Özkan Danış, Ayşe Ogan
Publikováno v:
Organic Communications. :356-377
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa8e3c1bd2a387b1a07c84bd8cc02273
https://doi.org/10.25135/acg.oc.142.2212.2651
https://doi.org/10.25135/acg.oc.142.2212.2651
Autor:
Abba Babandi, Chioma A. Anosike, Lawrence U.S. Ezeanyika, Kemal Yelekçi, Abdullahi Ibrahim Uba
Publikováno v:
Jordan Journal of Pharmaceutical Sciences. 15:258-275
The major obstacle in controlling malaria is the mosquito’s resistance to insecticides, including pyrethroids. The resistance is mainly due to the over-expression of detoxification enzymes such as cytochromes. Insecticides tolerance can be reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da50ed58e83ce85bf7fdf8820ac9f02b
https://doi.org/10.35516/jjps.v15i2.324
https://doi.org/10.35516/jjps.v15i2.324
Autor:
Bahadır Bülbül, Kai Ding, Chang-Guo Zhan, Gamze Çiftçi, Kemal Yelekçi, Merve Gürboğa, Özlem Bingöl Özakpınar, Esra Aydemir, Deniz Baybağ, Fikrettin Şahin, Necla Kulabaş, Sinem Helvacıoğlu, Mohammad Charehsaz, Esra Tatar, Süheyla Özbey, İlkay Küçükgüzel
Publikováno v:
Molecular Diversity.
Abstract: Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, human lung cancer A549, human prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fff10ce342b135087a7b4b61999282
https://doi.org/10.1007/s11030-022-10551-0
https://doi.org/10.1007/s11030-022-10551-0
Autor:
Kemal Yelekçi, Safiye Sağ Erdem
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726f900b099cc1315f9ab16e80a3395c
https://doi.org/10.1007/978-1-0716-2643-6_17
https://doi.org/10.1007/978-1-0716-2643-6_17
Autor:
Kemal, Yelekçi, Safiye Sağ, Erdem
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2558
Proper elucidation of drug-target interaction is one of the most significant steps at the early stages of the drug development research. Computer-aided drug design tools have substantial contribution to this stage. In this chapter, we specifically co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c97d61a298095964e1eb631a2bbb1294
https://pubmed.ncbi.nlm.nih.gov/36169867
https://pubmed.ncbi.nlm.nih.gov/36169867
Publikováno v:
Journal of Molecular Structure. :135876
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a781267add9e8ef780e28ccc1caa42
https://doi.org/10.1016/j.molstruc.2023.135876
https://doi.org/10.1016/j.molstruc.2023.135876
Autor:
Sarah Boumezber, Kemal Yelekçi
Publikováno v:
Journal of biomolecular structuredynamics.
NO, or nitric oxide, is produced by a family of enzymes called nitric oxide synthase (NOS) from L-arginine. NO regulates many physiological functions such as smooth muscle relaxation, immune defense, and memory function. The overproduction of NO by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d651b001997f4471a1f59da58ef0b4
https://pubmed.ncbi.nlm.nih.gov/35322764
https://pubmed.ncbi.nlm.nih.gov/35322764