Zobrazeno 1 - 10
of 1 310
pro vyhledávání: '"KELLY, J.M."'
Autor:
Abacha, Yabalu Z., Forkuo, A.D., Gbedema, S.Y., Mittal, N., Ottilie, S., Rocamora, F., Winzeler, E.A., van Schalkwyk, D.A., Kelly, J.M., Taylor, M.C., Reader, J., Birkholtz, L-M., Lisgarten, D.R., Cockcroft, J.K., Lisgarten, J.N., Palmer, R.A., Talbert, R.C., Shnyder, Steven, Wright, Colin W.
Yes
The prospect of eradicating malaria continues to be challenging in the face of increasing parasite resistance to antimalarial drugs so that novel antimalarials active against asexual, sexual, and liver-stage malaria parasites are urgently ne
The prospect of eradicating malaria continues to be challenging in the face of increasing parasite resistance to antimalarial drugs so that novel antimalarials active against asexual, sexual, and liver-stage malaria parasites are urgently ne
Externí odkaz:
http://hdl.handle.net/10454/18930
Autor:
Sola, I., Artigas, A., Taylor, M.C., Perez-Areales, F.J., Viayna, E., Clos, M.V., Perez, B., Wright, Colin W., Kelly, J.M., Muñoz-Torrero, D.
Yes
Current drugs against human African trypanosomiasis (HAT) suffer from several serious drawbacks. The search for novel, effective, brain permeable, safe, and inexpensive antitrypanosomal compounds is therefore an urgent need. We have recently
Current drugs against human African trypanosomiasis (HAT) suffer from several serious drawbacks. The search for novel, effective, brain permeable, safe, and inexpensive antitrypanosomal compounds is therefore an urgent need. We have recently
Externí odkaz:
http://hdl.handle.net/10454/8940
Autor:
Sola, I., Castellà, S., Viayna, E., Galdeano, C., Taylor, M.C., Gbedema, Stephen Y., Pérez, B., Clos, M.V., Jones, D.C., Fairlamb, A.H., Wright, Colin W., Kelly, J.M., Muñoz-Torrero, D.
Yes
Dual submicromolar trypanocidal–antiplasmodial compounds have been identified by screening and chemical synthesis of 4-aminoquinoline-based heterodimeric compounds of three different structural classes. In Trypanosoma brucei, inhibition of
Dual submicromolar trypanocidal–antiplasmodial compounds have been identified by screening and chemical synthesis of 4-aminoquinoline-based heterodimeric compounds of three different structural classes. In Trypanosoma brucei, inhibition of
Externí odkaz:
http://hdl.handle.net/10454/7485
Autor:
Sola, I., Artigas, A., Taylor, M.C., Gbedema, Stephen Y., Perez, B., Clos, M.V., Wright, Colin W., Kelly, J.M., Muñoz-Torrero, D.
We have synthesized a series of dimers of (+)-(7R,11R)-huprine Y and evaluated their activity against Trypanosoma brucei, Plasmodium falciparum, rat myoblast L6 cells and human acetylcholinesterase (hAChE), and their brain permeability. Most dimers h
Externí odkaz:
http://hdl.handle.net/10454/7496
Autor:
Defaux, J., Sala, M., Formosa, X., Galdeano, C., Taylor, M.C., Kelly, J.M., Wright, Colin W., Camps, P., Muñoz-Torrero, D., Alobaid, Waleed A.A.
A series of 19 huprines has been evaluated for their activity against cultured bloodstream forms of Trypanosoma brucei and Plasmodium falciparum. Moreover, cytotoxicity against rat myoblast L6 cells was assessed for selected huprines. All the tested
Externí odkaz:
http://hdl.handle.net/10454/7468
Autor:
Thys, Kelly J.M., Vanhove, Maarten P.M., Custers, Jonas W.J., Vranken, Nathan, Van Steenberge, Maarten, Kmentová, Nikol
Publikováno v:
In International Journal for Parasitology November 2022 52(12):775-786
Publikováno v:
In Livestock Science June 2022 260
Publikováno v:
In Nuclear Inst. and Methods in Physics Research, A 1 January 2021 985
Publikováno v:
In Nuclear Inst. and Methods in Physics Research, B 15 January 2020 463:485-487